Zobrazeno 1 - 8
of 8
pro vyhledávání: '"David A. Gascoigne"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
The regulation of oxygen in brain tissue is one of the most important fundamental questions in neuroscience and medicine. The brain is a metabolically demanding organ, and its health directly depends on maintaining oxygen concentrations within a rela
Externí odkaz:
https://doaj.org/article/713c39615ece4fd0a8c7d606bb7f4144
Autor:
Daniil P. Aksenov, Evan D. Doubovikov, Natalya A. Serdyukova, David A. Gascoigne, Robert A. Linsenmeier, Alexander Drobyshevsky
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
The dynamic interaction between excitatory and inhibitory activity in the brain is known as excitatory-inhibitory balance (EIB). A significant shift in EIB toward excitation has been observed in numerous pathological states and diseases, such as auti
Externí odkaz:
https://doaj.org/article/808f561804b246f0bebad43edddaa610
Autor:
Evan D. Doubovikov, Natalya A. Serdyukova, Steven B. Greenberg, David A. Gascoigne, Mohammed M. Minhaj, Daniil P. Aksenov
Publikováno v:
Cells, Vol 12, Iss 18, p 2229 (2023)
Electric fields are now considered a major mechanism of epileptiform activity. However, it is not clear if another electrophysiological phenomenon, burst suppression, utilizes the same mechanism for its bursting phase. Thus, the purpose of this study
Externí odkaz:
https://doaj.org/article/dfa0626993514317817ebebf68343fb5
Autor:
Daniil P. Aksenov, Limin Li, Natalya A. Serdyukova, David A. Gascoigne, Evan D. Doubovikov, Alexander Drobyshevsky
Publikováno v:
Cells, Vol 12, Iss 5, p 811 (2023)
The functional deficiency of the inhibitory system typically appears during development and can progress to psychiatric disorders or epilepsy, depending on its severity, in later years. It is known that interneurons, the major source of GABAergic inh
Externí odkaz:
https://doaj.org/article/b7d78f1a5cbf4a728d9c27f51511a529
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/e25775f00f1f4abcb4a1b5029bd2523a
Publikováno v:
Antioxidants, Vol 11, Iss 4, p 787 (2022)
Neonatal anesthesia, while often essential for surgeries or imaging procedures, is accompanied by significant risks to redox balance in the brain due to the relatively weak antioxidant system in children. Oxidative stress is characterized by concentr
Externí odkaz:
https://doaj.org/article/4a1fb3c22f684129beee352dd9d3630b
Publikováno v:
The Lancet Child & Adolescent Health. 7:6-8
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 12951, p 12951 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 12951, p 12951 (2021)
Human and animal studies have elucidated the apparent neurodevelopmental effects resulting from neonatal anesthesia. Observations of learning and behavioral deficits in children, who were exposed to anesthesia early in development, have instigated a