Zobrazeno 1 - 10
of 358
pro vyhledávání: '"David A. Gagnon"'
Autor:
Patrick J. Coppler, David J. Gagnon, Katharyn L. Flickinger, Jonathan Elmer, Clifton W. Callaway, Francis X. Guyette, Ankur Doshi, Alexis Steinberg, Cameron Dezfulian, Ari L. Moskowitz, Michael Donnino, Teresa L. May, David B. Seder, Jon C. Rittenberger
Publikováno v:
Clinical and Experimental Emergency Medicine, Vol 11, Iss 2, Pp 205-212 (2024)
Objective We hypothesized that the administration of amantadine would increase awakening of comatose patients resuscitated from cardiac arrest. Methods We performed a prospective, randomized, controlled pilot trial, randomizing subjects to amantadine
Externí odkaz:
https://doaj.org/article/167fa17356a04a76bb9d4eb2aa7cad80
Publikováno v:
American Journal of Preventive Cardiology, Vol 19, Iss , Pp 100718- (2024)
The impact of smoking cessation on long-term clinical outcomes after contemporary percutaneous coronary intervention (PCI) is not well known. We estimated the association of smoking and smoking cessation on the 10-year risk of cardiovascular and non-
Externí odkaz:
https://doaj.org/article/0af5be4ff75242458496100fc55435d9
Autor:
Saadia Qazi, Benjamin Seligman, Sarah R. Preis, Manas Rane, Luc Djousse, David R. Gagnon, Peter W. F. Wilson, J. Michael Gaziano, Jane A. Driver, Kelly Cho, Ariela R. Orkaby
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 16 (2024)
Background Frailty, a syndrome of physiologic vulnerability, increases cardiovascular disease (CVD) risk. Whether in person or automated frailty tools are ideal for identifying CVD risk remains unclear. We calculated 3 distinct frailty scores and exa
Externí odkaz:
https://doaj.org/article/0f241e944ac142269d71e4636d86591a
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 14 (2024)
Background Heart failure with preserved ejection fraction (HFpEF) is a complex syndrome increasing in prevalence and affecting millions worldwide but with limited evidence‐based therapies. Results from explanatory clinical trials suggest that spiro
Externí odkaz:
https://doaj.org/article/b7a1361975b745c68e3f4cc43e642e06
Autor:
Darae Ko, Timothy M. Treu, Laura Tarko, Yuk-Lam Ho, Sarah R. Preis, Ludovic Trinquart, David R. Gagnon, Kevin M. Monahan, Robert H. Helm, Ariela R. Orkaby, Steven A. Lubitz, Nicholas A. Bosch, Allan J. Walkey, Kelly Cho, Peter W. F. Wilson, Emelia J. Benjamin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Most prior studies on the prognostic significance of newly-diagnosed atrial fibrillation (AF) in COVID-19 did not differentiate newly-diagnosed AF from pre-existing AF. To determine the association between newly-diagnosed AF and in-hospital
Externí odkaz:
https://doaj.org/article/880401f8ca1d463abbbe1f9236f16ddc
Autor:
Xuan‐Mai T. Nguyen, Yuk‐Lam Ho, Yanping Li, Rebecca J. Song, Kenneth H. Leung, Saad Ur Rahman, Ariela R. Orkaby, Jason L. Vassy, David R. Gagnon, Kelly Cho, J. Michael Gaziano, Peter W. F. Wilson
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 21 (2023)
Background The lipid hypothesis postulates that lower blood cholesterol is associated with reduced coronary heart disease (CHD) risk, which has been challenged by reports of a U‐shaped relation between cholesterol and death in recent studies. We so
Externí odkaz:
https://doaj.org/article/7e602f134e2a43518206addd4e15bf63
Autor:
Ji Tong Liu, PharmD, BCCCP, Caitlin S. Brown, PharmD, BCCCP, FCCM, Kristin C. Mara, MS, Richard R. Riker, MD, FCCM, Alejandro A. Rabinstein, MD, Gilles L. Fraser, PharmD, MCCM, Teresa L. May, DO, Kaitlin J. Armstrong, PharmD, David B. Seder, MD, FCCM, David J. Gagnon, PharmD, BCCCP, FCCM
Publikováno v:
Critical Care Explorations, Vol 5, Iss 10, p e0987 (2023)
IMPORTANCE:. Protein binding of valproate varies among ICU patients, altering the biologically active free valproate concentration (VPAC). Free VPAC is measured at few laboratories and is often discordant with total VPAC. Existing equations to predic
Externí odkaz:
https://doaj.org/article/e1a61f73edfc455a9251a6987de219bf
NEW STATIN USE IS ASSOCIATED WITH A LOWER RISK OF INCIDENT FRAILTY IN US VETERANS 65 YEARS AND OLDER
Autor:
Saadia Qazi, DO, MPH, Michel Farah, MD, Brian Charest, MS, MPH, Jane A. Driver, MD, MPH, J. Michael Gaziano, MD, MPH, Peter W.F. Wilson, MD, Kelly Cho, PhD, Luc Djousse, MD, ScD, David R Gagnon, MD PhD, Ariela R. Orkaby, MD, MPH
Publikováno v:
American Journal of Preventive Cardiology, Vol 15, Iss , Pp 100540- (2023)
Therapeutic Area: CVD Prevention – Primary and Secondary Background: Frailty is a syndrome of decreased physiologic reserve that is increasingly recognized as a risk factor for cardiovascular disease (CVD), yet no pharmacotherapeutics are available
Externí odkaz:
https://doaj.org/article/a94bdbb6d6d044b4a858942edb6b827e
Autor:
Brian Ferolito, Italo Faria do Valle, Hanna Gerlovin, Lauren Costa, Juan P. Casas, J. Michael Gaziano, David R. Gagnon, Edmon Begoli, Albert-László Barabási, Kelly Cho
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Understanding the genetic relationships between human disorders could lead to better treatment and prevention strategies, especially for individuals with multiple comorbidities. A common resource for studying genetic-disease relationships is
Externí odkaz:
https://doaj.org/article/dbd109338c14435f91d75def3d6b5ff8
Autor:
Italo Faria do Valle, Brian Ferolito, Hanna Gerlovin, Lauren Costa, Serkalem Demissie, Franciel Linares, Jeremy Cohen, David R. Gagnon, J. Michael Gaziano, Edmon Begoli, Kelly Cho, Albert-László Barabási
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract A better understanding of the sequential and temporal aspects in which diseases occur in patient’s lives is essential for developing improved intervention strategies that reduce burden and increase the quality of health services. Here we p
Externí odkaz:
https://doaj.org/article/d1a1df5fcb16439eb4d791e2f8c0f53e