Zobrazeno 1 - 10
of 1 656
pro vyhledávání: '"David A. Fisher"'
Autor:
Jason Desmarais, MD, David Dalury, MD, Thomas L. Bernasek, MD, David A. Fisher, MD, Ryan M. Nunley, MD, Marie-Claire Fickenscher, MS, Robert S. Gorab, MD
Publikováno v:
Arthroplasty Today, Vol 15, Iss , Pp 34-39 (2022)
Background: Uncemented total knee arthroplasty is increasing as a potential solution for aseptic loosening via biologic fixation and to increase operative efficiency. However, postoperative radiolucent lines (RLLs) remain a concern for some clinician
Externí odkaz:
https://doaj.org/article/bdcf53054b5b415bbf463e8b2c10590a
Publikováno v:
Communications Earth & Environment, Vol 3, Iss 1, Pp 1-12 (2022)
Frost susceptibility of permafrost sediments is strongly influenced by unfrozen water content, which is dependent on sediment type, soil water chemistry, and temperature, according to field observations and ensemble modeling prediction of ground ice
Externí odkaz:
https://doaj.org/article/b4a64a89aa6c48cb84cb80496f0d44fc
Publikováno v:
Arctic, Antarctic, and Alpine Research, Vol 53, Iss 1, Pp 324-339 (2021)
Climate change is impacting lakes and ponds in Antarctica. To that end, we investigated the distribution and chemical composition of ice-covered ponds in Untersee Oasis, East Antarctica. Thirty-nine ponds were inventoried, and the thirteen sampled po
Externí odkaz:
https://doaj.org/article/a64ca06215a4426eac0c49e4bdb7d8f2
Publikováno v:
Frontiers in Earth Science, Vol 8 (2020)
Perennially ice-covered lakes that are tightly sealed from the atmosphere represent a unique group of polar lakes. In these lakes, the δD-δ18O evolution of the water column and steady-state conditions are controlled by rates of recharge and freezin
Externí odkaz:
https://doaj.org/article/f2fb451c90a24b19a90fc4eff2f6aeda
Autor:
Elisabeth Roider, Alexandra I. T. Lakatos, Alicia M. McConnell, Poguang Wang, Alina Mueller, Akinori Kawakami, Jennifer Tsoi, Botond L. Szabolcs, Anna A. Ascsillán, Yusuke Suita, Vivien Igras, Jennifer A. Lo, Jennifer J. Hsiao, Rebecca Lapides, Dorottya M. P. Pál, Anna S. Lengyel, Alexander Navarini, Arimichi Okazaki, Othon Iliopoulos, István Németh, Thomas G. Graeber, Leonard Zon, Roger W. Giese, Lajos V. Kemeny, David E. Fisher
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Microphthalmia-associated transcription factor (MITF) is a master regulator of melanocyte function, development and plays a significant role in melanoma pathogenesis. MITF genomic amplification promotes melanoma development, and it can facil
Externí odkaz:
https://doaj.org/article/cc94d2d3111647cfb25391c16c6a03e3
Autor:
Kanika Kamal, David Xiang, Katherine Young, David E. Fisher, Arash Mostaghimi, Nicholas Theodosakis
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 8, Pp 2109-2117 (2024)
Abstract Introduction Limited epidemiologic data has suggested direct associations between hair pigment, race, and incidence of alopecia areata (AA). Here, we examine the relationship between natural hair color, race, and the lifetime risk alopecia.
Externí odkaz:
https://doaj.org/article/711eef10c46e41d6953e3cb2caf67320
Autor:
Thomas G. Hayhow, Beth Williamson, Mandy Lawson, Natalie Cureton, Erin L. Braybrooke, Andrew Campbell, Rodrigo J. Carbajo, Azadeh Cheraghchi-Bashi, Elisabetta Chiarparin, Coura R. Diène, Charlene Fallan, David I. Fisher, Frederick W. Goldberg, Lorna Hopcroft, Philip Hopcroft, Anne Jackson, Jason G. Kettle, Teresa Klinowska, Ulrike Künzel, Gillian Lamont, Hilary J. Lewis, Gareth Maglennon, Scott Martin, Pablo Morentin Gutierrez, Christopher J. Morrow, Myria Nikolaou, J. Willem M. Nissink, Patrick O’Shea, Radoslaw Polanski, Markus Schade, James S. Scott, Aaron Smith, Judith Weber, Joanne Wilson, Bin Yang, Claire Crafter
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Targeting the estrogen receptor alpha (ERα) pathway is validated in the clinic as an effective means to treat ER+ breast cancers. Here we present the development of a VHL-targeting and orally bioavailable proteolysis-targeting chimera (PROT
Externí odkaz:
https://doaj.org/article/ec006f9560824ea494be6041bb1eeb60
Autor:
Jerry Shen, BASc, MASc, David M. Fisher, FRCSC, FACS, Branavan Yasabala, BEng, Karen W.Y. Wong Riff, MD, PhD, FRCSC, Dale J. Podolsky, MD, PhD, FRCSC
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 11, Iss 10, p e5363 (2023)
Summary:. Alveolar bone graft (ABG) surgery in cleft patients is technically challenging. The procedure requires design, dissection and release of soft tissue flaps to create a seal around the bone graft. In addition, visualization during the procedu
Externí odkaz:
https://doaj.org/article/bc07a48128d84c12bfc8b0ceb9a4cc5d
Autor:
Deepti Gadi, Stephen P. Martindale, Pui Yan Chiu, Jasneet Khalsa, Pei-Hsuan Chen, Stacey M. Fernandes, Zixu Wang, Svitlana Tyekucheva, John-Hanson Machado, David C. Fisher, Philippe Armand, Matthew S. Davids, Scott Rodig, Barbara Sherry, Jennifer R. Brown
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract PI3Kδ inhibitors are approved for the therapy of B cell malignancies, but their clinical use has been limited by unpredictable autoimmune toxicity, despite promising efficacy and evidence that toxicity is associated with improved clinical o
Externí odkaz:
https://doaj.org/article/94914f0b3bca45c9ad51c3edd14b1ac9
Autor:
Sung-Hee Yoon, Mark B. Meyer, Carlos Arevalo, Murat Tekguc, Chengcheng Zhang, Jialiang S. Wang, Christian D. Castro Andrade, Katelyn Strauss, Tadatoshi Sato, Nancy A. Benkusky, Seong Min Lee, Rebecca Berdeaux, Marc Foretz, Thomas B. Sundberg, Ramnik J. Xavier, Charles H. Adelmann, Daniel J. Brooks, Anthony Anselmo, Ruslan I. Sadreyev, Ivy A. Rosales, David E. Fisher, Navin Gupta, Ryuji Morizane, Anna Greka, J. Wesley Pike, Michael Mannstadt, Marc N. Wein
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 9 (2023)
The renal actions of parathyroid hormone (PTH) promote 1,25-vitamin D generation; however, the signaling mechanisms that control PTH-dependent vitamin D activation remain unknown. Here, we demonstrated that salt-inducible kinases (SIKs) orchestrated
Externí odkaz:
https://doaj.org/article/807eb29db7bc4680b7215fddd31857a3