Výsledky vyhledávání - "David A. Fela"

Topical N-acetyl-S-farnesyl-L-cysteine Inhibits Mouse Skin Inflammation, and Unlike Dexamethasone, its Effects Are Restricted to the Application Site

Autor: Eduardo Perez, David A. Fela, Maxwell Stock, Arnold V. Gonzalez, Jeffry B. Stock, Karl Rouzard, Joel S. Gordon, Gopal Sarngadharan, Peter M. Wolanin

Publikováno v: Journal of Investigative Dermatology. 128(3):643-654

N-acetyl-S-farnesyl-L-cysteine (AFC), a modulator of G protein and G-protein coupled receptor signaling, inhibits neutrophil chemotaxis and other inflammatory responses in cell-based assays. Here, we show topical AFC inhibits in vivo acute inflammati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847acbabd5e5f54e4e6e3acc63fad9cc

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Single-Cell Analysis of Diverse Pathogen Responses Defines a Molecular Roadmap for Generating Antigen-Specific Immunity

Autor: Pierre Bost, Eyal David, Ido Amit, Ronnie Blecher-Gonen, Franca Ronchese, Tomer-Meir Salame, Johannes U Mayer, Keren Bahar Halpern, Kerry L. Hilligan, Beáta Tóth, Benno Schwikowski, Shalev Itzkovitz, Lisa M. Connor, Elsa Roussel

Publikováno v: Cell Systems
Cell Systems, Elsevier, 2019, 8 (2), pp.109-121.e6. ⟨10.1016/j.cels.2019.01.001⟩
Cell Systems, 2019, 8 (2), pp.109-121.e6. ⟨10.1016/j.cels.2019.01.001⟩

International audience; The immune system generates pathogen-tailored responses. The precise innate immune cell types and pathways that direct robust adaptive immune responses have not been fully characterized. By using fluorescent pathogens combined

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8c86dd9abc5e3b22c50c0c5934524c
https://hal-pasteur.archives-ouvertes.fr/pasteur-02965324

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