Výsledky vyhledávání - "David A. Favor"

Total Synthesis of (+)-Azaspiracid-1. An Exhibition of the Intricacies of Complex Molecule Synthesis

Autor: David A. Evans, Edward J. Olhava, Travis B. Dunn, Lisbet Kværnø, André Beauchemin, Martin Juhl, Brian Raymer, Katsuji Kagechika, David A. Favor, Jason A. Mulder

Publikováno v: Journal of the American Chemical Society. 130:16295-16309

The synthesis of the marine neurotoxin azaspiracid-1 has been accomplished. The individual fragments were synthesized by catalytic enantioselective processes: A hetero-Diels-Alder reaction to afford the E- and HI-ring fragments, a carbonyl-ene reacti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3bba190ba29a4c85c1370cd30f5dc3
https://doi.org/10.1021/ja804659n

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A second-generation synthesis of scalemic 3,5,5-trisubstituted pyrrolin-4-ones: Incorporation of functionalized amino acid side-chains

Autor: Andrew B. Benowitz, Ralph Hirschmann, Amos B. Smith, Paul A. Sprengeler, David A. Favor

Publikováno v: Tetrahedron Letters. 38:3809-3812

To access mimics of peptidal β-strands ( 1 ), scalemic 3,5,5-trisubstituted pyrrolin-4-ones bearing the tyrosine, serine, and lysine side-chains have been generated via cyclization of metalated imino esters and deprotection. The functionalized imino

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eacaf09973334cb53a02f76405d63c1a
https://doi.org/10.1016/s0040-4039(97)00752-1

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ChemInform Abstract: A Second-Generation Synthesis of Scalemic 3,5,5-Trisubstituted Pyrrolin-4-ones: Incorporation of Functionalized Amino Acid Side- Chains

Autor: Amos B. Smith, Paul A. Sprengeler, David A. Favor, Ralph Hirschmann, Andrew B. Benowitz

Publikováno v: ChemInform. 28

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85dc8050c9c23f6b1a0dc8ddb397b212
https://doi.org/10.1002/chin.199736224

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ChemInform Abstract: Azide and Cyanide Displacements via Hypervalent Silicate Intermediates

Autor: Philip DeShong, Amy S. Manoso, Michael C. Patterson, Ralph Hirschmann, David A. Favor, Eric D. Soli, Amos B. Smith

Publikováno v: ChemInform. 30

Hypervalent azido- and cyanosilicate derivatives, prepared in situ by the reaction of trimethylsilyl azide or trimethylsilyl cyanide, respectively, with tetrabutylammonium fluoride, are effective sources of nucleophilic azide or cyanide. Primary and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ef72261124860acd726e50a5ccc024cf
https://doi.org/10.1002/chin.199937030

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