Zobrazeno 1 - 10
of 47
pro vyhledávání: '"David A. Dwyer"'
Autor:
Kenneth Y. Tsai, Nizar M. Tannir, Naifa L. Busaidy, Madeleine Duvic, Ana M. Ciurea, Jonathan L. Curry, Rosamaria Ruggieri, Manuela Baccarini, Karin Ehrenreiter, Haiching Ma, David W. Dwyer, Vida Chitsazzadeh, Charles H. Adelmann, Sandra S. Ojeda, Grace Ching, Harina Vin
PDF - 69KB, In-vitro kinase assays were performed against sorafenib with a staurosporine positive control across a concentration range of 0.5 nM to 10 μM). Blank values are those for which no significant inhibition occurred over the entire concentra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b88de25d705152f0908a5d78921600fc
https://doi.org/10.1158/1535-7163.22503256.v1
https://doi.org/10.1158/1535-7163.22503256.v1
Autor:
Kenneth Y. Tsai, Nizar M. Tannir, Naifa L. Busaidy, Madeleine Duvic, Ana M. Ciurea, Jonathan L. Curry, Rosamaria Ruggieri, Manuela Baccarini, Karin Ehrenreiter, Haiching Ma, David W. Dwyer, Vida Chitsazzadeh, Charles H. Adelmann, Sandra S. Ojeda, Grace Ching, Harina Vin
PDF - 1060KB, Sorafenib suppresses JNK-dependent apoptosis as assessed by cleaved caspase 3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f52bce56824158bd5240f1f3eaebe33
https://doi.org/10.1158/1535-7163.22503259
https://doi.org/10.1158/1535-7163.22503259
Autor:
Andrew B. Kennedy, David L. Dwyer
Publikováno v:
The Pacific Review. 35:147-171
Technological innovation has emerged as an important site of globalization in recent decades. Yet it is unclear what the future holds for this new form of collaboration, given the spectre of high-t...
Autor:
Harina Vin, Sandra S Ojeda, Grace Ching, Marco L Leung, Vida Chitsazzadeh, David W Dwyer, Charles H Adelmann, Monica Restrepo, Kristen N Richards, Larissa R Stewart, Lili Du, Scarlett B Ferguson, Deepavali Chakravarti, Karin Ehrenreiter, Manuela Baccarini, Rosamaria Ruggieri, Jonathan L Curry, Kevin B Kim, Ana M Ciurea, Madeleine Duvic, Victor G Prieto, Stephen E Ullrich, Kevin N Dalby, Elsa R Flores, Kenneth Y Tsai
Publikováno v:
eLife, Vol 2 (2013)
Vemurafenib and dabrafenib selectively inhibit the v-Raf murine sarcoma viral oncogene homolog B1 (BRAF) kinase, resulting in high response rates and increased survival in melanoma. Approximately 22% of individuals treated with vemurafenib develop cu
Externí odkaz:
https://doaj.org/article/b82986af3d064ca596c82909e620f375
Publikováno v:
The Journal of Immunology. 173:2923-2927
Naive CD8+ T cells are activated on encounter with Ag presented on dendritic cells and proliferate rapidly. To investigate the regulation of naive CD8+ T cells proliferation, we adoptively transferred TCR-transgenic CD8+ T cells into intact mice toge
Autor:
Michael M. Cox, Joshua Korth, Lily Abbott, Christopher D. Fleming, Shelley L. Lusetti, Ross B. Inman, Alberto I. Roca, Elizabeth A. Wood, David W. Dwyer, Michael J. Modica
Publikováno v:
Journal of Biological Chemistry. 278:16372-16380
A set of C-terminal deletion mutants of the RecA protein of Escherichia coli, progressively removing 6, 13, 17, and 25 amino acid residues, has been generated, expressed, and purified. In vivo, the deletion of 13 to 17 C-terminal residues results in
Autor:
Jong-Il Kim, Michael M. Cox, Ross B. Inman, Stephen N. Abbott, Aaron Jambura, David W. Dwyer, Ajay K. Sharma, Elizabeth A. Wood, Michael J. Daly, Kenneth W. Minton
Publikováno v:
Journal of Bacteriology. 184:1649-1660
The RecA protein of Deinococcus radiodurans (RecA Dr ) is essential for the extreme radiation resistance of this organism. The RecA Dr protein has been cloned and expressed in Escherichia coli and purified from this host. In some respects, the RecA D
Publikováno v:
The Journal of Physical Chemistry A. 104:7629-7634
In previous work from our laboratories we have characterized the molecular motion of phenalenyl in the supercage of cation-exchanged X- and Y-zeolites using continuous wave−electron paramagnetic resonance (CW-EPR) and pulsed-EPR techniques. The tre
Autor:
David J. Dwyer
Publikováno v:
Issue. 25:23-28
Support for academic African language programs (ALPs) in the US began at the national level with the National Defense Education Act of 1958 (renamed the Higher Education Act of 1965). The goal of this legislation was to establish a world-wide languag
Publikováno v:
Studying Teachers' Lives ISBN: 9780203415177
Beyond the particular substantive concepts one uses to order the personality of the teachers and administrators engaged in school improvement a further issue lies in the form which those concepts take. Mischel1 in the second edition of his Introducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44ceb32ab4e6ad08c60aaa1044d0d5bc
https://doi.org/10.4324/9780203415177-12
https://doi.org/10.4324/9780203415177-12