Zobrazeno 1 - 4
of 4
pro vyhledávání: '"David A. Droppleman"'
Autor:
Pauline L. Martin, Richard J. Barrett, Kathryn F. Wright, D. Mossem, David A. Droppleman, A M Sykes
Publikováno v:
Drug Development Research. 42:76-85
2-[(cyclohexylmethylene)hydrazino]adenosine (MRE-0470) is an A 2 -adenosine receptor agonist that is a potent and selective coronary vasodilator. As part of a preclinical program, the pharmacology and toxicology of MRE-0470 have been studied in the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b4e87c2409812e03e8673e4f60e007a
https://doi.org/10.1002/(sici)1098-2299(199710)42:2<76::aid-ddr4>3.0.co
https://doi.org/10.1002/(sici)1098-2299(199710)42:2<76::aid-ddr4>3.0.co
Publikováno v:
Drug Development Research. 32:196-203
The renal hemodynamic and excretory effects of intravenous N-0861, a non-xanthine adenosine A1-receptor antagonist, were evaluated in conscious and anesthetized male Sprague-Dawely rats. In conscious rats, N-0861 (10, 30 μmol/kg, iv) significantly i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24b886627130e484c4f6b38ccfb4e968
https://doi.org/10.1002/ddr.430320310
https://doi.org/10.1002/ddr.430320310
Publikováno v:
European Journal of Pharmacology. 216:9-16
Experiments were performed to determine the antagonistic actions of (+/-)N6-endonorbornan-2-yl-9-methyladenine (N-0861) at A1 and A2 adenosine receptors in vivo, and to evaluate the pharmacodynamics of the observed responses. The selectivity of antag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6ec7b2246166155f3de4407d594193
https://doi.org/10.1016/0014-2999(92)90202-f
https://doi.org/10.1016/0014-2999(92)90202-f
Autor:
Reevis S. Alphin, David A. Droppleman
Publikováno v:
European Journal of Pharmacology. 41:235-237
The role of pepsin proteolytic activity in the Exalto-Mann-Williamson ulcer has previously not been established. Our studies show that a potent inhibitor of pepsin activity, when administered orally to E-M-W dogs, reduced both the incidence and sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39dc9886979fbe6a040ec38e466c2b05
https://doi.org/10.1016/0014-2999(77)90216-3
https://doi.org/10.1016/0014-2999(77)90216-3