Zobrazeno 1 - 10
of 369
pro vyhledávání: '"David A. Drew"'
Autor:
Nikos Papadimitriou, Andre Kim, Eric S. Kawaguchi, John Morrison, Virginia Diez-Obrero, Demetrius Albanes, Sonja I. Berndt, Stéphane Bézieau, Stephanie A. Bien, D Timothy Bishop, Emmanouil Bouras, Hermann Brenner, Daniel D. Buchanan, Peter T. Campbell, Robert Carreras-Torres, Andrew T. Chan, Jenny Chang-Claude, David V. Conti, Matthew A. Devall, Niki Dimou, David A. Drew, Stephen B. Gruber, Tabitha A. Harrison, Michael Hoffmeister, Jeroen R. Huyghe, Amit D. Joshi, Temitope O. Keku, Anshul Kundaje, Sébastien Küry, Loic Le Marchand, Juan Pablo Lewinger, Li Li, Brigid M. Lynch, Victor Moreno, Christina C. Newton, Mireia Obón-Santacana, Jennifer Ose, Andrew J. Pellatt, Anita R. Peoples, Elizabeth A. Platz, Conghui Qu, Gad Rennert, Edward Ruiz-Narvaez, Anna Shcherbina, Mariana C. Stern, Yu-Ru Su, Duncan C. Thomas, Claire E. Thomas, Yu Tian, Konstantinos K. Tsilidis, Cornelia M. Ulrich, Caroline Y. Um, Kala Visvanathan, Jun Wang, Emily White, Michael O. Woods, Stephanie L. Schmit, Finlay Macrae, John D. Potter, John L. Hopper, Ulrike Peters, Neil Murphy, Li Hsu, Marc J. Gunter, W. James Gauderman
Publikováno v:
EBioMedicine, Vol 104, Iss , Pp 105146- (2024)
Summary: Background: Consumption of fibre, fruits and vegetables have been linked with lower colorectal cancer (CRC) risk. A genome-wide gene-environment (G × E) analysis was performed to test whether genetic variants modify these associations. Meth
Externí odkaz:
https://doaj.org/article/6e63530a90ca4cdaa69e0f9d74663f4a
Autor:
Seba Babroudi, MD, Joshua Hyun Bin Whang, BA, Avery C. Glover, MD, MBA, Tamara Vesel, MD, David A. Drew, MD, MS
Publikováno v:
Kidney Medicine, Vol 6, Iss 5, Pp 100818- (2024)
Externí odkaz:
https://doaj.org/article/a8f00ab097d345bba26cfe9f8afe0c2d
Autor:
Nikos Papadimitriou, Conghui Qu, Tabitha A. Harrison, Alaina M. Bever, Richard M. Martin, Konstantinos K. Tsilidis, Polly A. Newcomb, Stephen N. Thibodeau, Christina C. Newton, Caroline Y. Um, Mireia Obón-Santacana, Victor Moreno, Hermann Brenner, Marko Mandic, Jenny Chang-Claude, Michael Hoffmeister, Andrew J. Pellatt, Robert E. Schoen, Sophia Harlid, Shuji Ogino, Tomotaka Ugai, Daniel D. Buchanan, Brigid M. Lynch, Stephen B. Gruber, Yin Cao, Li Hsu, Jeroen R. Huyghe, Yi Lin, Robert S. Steinfelder, Wei Sun, Bethany Van Guelpen, Syed H. Zaidi, Amanda E. Toland, Sonja I. Berndt, Wen-Yi Huang, Elom K. Aglago, David A. Drew, Amy J. French, Peter Georgeson, Marios Giannakis, Meredith Hullar, Johnathan A. Nowak, Claire E. Thomas, Loic Le Marchand, Iona Cheng, Steven Gallinger, Mark A. Jenkins, Marc J. Gunter, Peter T. Campbell, Ulrike Peters, Mingyang Song, Amanda I. Phipps, Neil Murphy
Publikováno v:
EBioMedicine, Vol 101, Iss , Pp 105010- (2024)
Summary: Background: Obesity has been positively associated with most molecular subtypes of colorectal cancer (CRC); however, the magnitude and the causality of these associations is uncertain. Methods: We used Mendelian randomization (MR) to examine
Externí odkaz:
https://doaj.org/article/8a3379fc34b648e7a0fa5d9ca98ea9f7
Autor:
Long H. Nguyen, Daniel Okin, David A. Drew, Vincent M. Battista, Sirus J. Jesudasen, Thomas M. Kuntz, Amrisha Bhosle, Kelsey N. Thompson, Trenton Reinicke, Chun-Han Lo, Jacqueline E. Woo, Alexander Caraballo, Lorenzo Berra, Jacob Vieira, Ching-Ying Huang, Upasana Das Adhikari, Minsik Kim, Hui-Yu Sui, Marina Magicheva-Gupta, Lauren McIver, Marcia B. Goldberg, Douglas S. Kwon, Curtis Huttenhower, Andrew T. Chan, Peggy S. Lai
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background The gut microbiome is a critical modulator of host immunity and is linked to the immune response to respiratory viral infections. However, few studies have gone beyond describing broad compositional alterations in severe COVID-19,
Externí odkaz:
https://doaj.org/article/afc3763a56b64dd68fea4cc56b2a2b90
Autor:
Yiqing Wang, Wenjie Ma, Raaj Mehta, Long H. Nguyen, Mingyang Song, David A. Drew, Francesco Asnicar, Curtis Huttenhower, Nicola Segata, Jonathan Wolf, Tim Spector, Sarah Berry, Kyle Staller, Andrew T. Chan
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTThe role of diet and the gut microbiome in the etiopathogenesis of irritable bowel syndrome (IBS) is not fully understood. Therefore, we investigated the interplay between dietary risk factors and gut microbiota in IBS subtypes using a food f
Externí odkaz:
https://doaj.org/article/33d24307162a4f43a499633f22fc3ddb
The Impact of the Gut Microbiome, Environment, and Diet in Early-Onset Colorectal Cancer Development
Autor:
Rui Dai, Bridget N. Kelly, Amarachi Ike, David Berger, Andrew Chan, David A. Drew, David Ljungman, David Mutiibwa, Rocco Ricciardi, Gerald Tumusiime, James C. Cusack
Publikováno v:
Cancers, Vol 16, Iss 3, p 676 (2024)
Traditionally considered a disease common in the older population, colorectal cancer is increasing in incidence among younger demographics. Evidence suggests that populational- and generational-level shifts in the composition of the human gut microbi
Externí odkaz:
https://doaj.org/article/d3da08275d8144febc9027e91ce8a412
Autor:
Raphael Vallat, Sarah E. Berry, Neli Tsereteli, Joan Capdevila, Haya Al Khatib, Ana M. Valdes, Linda M. Delahanty, David A. Drew, Andrew T. Chan, Jonathan Wolf, Paul W. Franks, Tim D. Spector, Matthew P. Walker
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
In a prospective longitudinal study of 833 adults, we demonstrate that how you wake up and regain alertness in the hours after sleep is weakly associated with your genes. Instead, the modifiable factors of how you are sleeping, eating and exercising
Externí odkaz:
https://doaj.org/article/244caa6f530342bda074f36516f0817b
Autor:
Silvia Ferrè, Yu-Lun Liu, Joshua W. Lambert, Ronit Katz, Fabiola G. Gianella, David A. Drew, Michael G. Shlipak, Orson W. Moe, Joachim H. Ix, Robert D. Toto, Javier A. Neyra
Publikováno v:
Kidney Medicine, Vol 5, Iss 6, Pp 100634- (2023)
Rationale and Objective: Serum magnesium levels have been inversely yet inconsistently associated with cardiovascular (CV) outcomes. In this study, we examined the association of serum magnesium levels with CV outcomes in the Systolic Blood Pressure
Externí odkaz:
https://doaj.org/article/bb693f4ef1c04a4e8628f6df1154d753
Autor:
Peter Georgeson, Tabitha A. Harrison, Bernard J. Pope, Syed H. Zaidi, Conghui Qu, Robert S. Steinfelder, Yi Lin, Jihoon E. Joo, Khalid Mahmood, Mark Clendenning, Romy Walker, Efrat L. Amitay, Sonja I. Berndt, Hermann Brenner, Peter T. Campbell, Yin Cao, Andrew T. Chan, Jenny Chang-Claude, Kimberly F. Doheny, David A. Drew, Jane C. Figueiredo, Amy J. French, Steven Gallinger, Marios Giannakis, Graham G. Giles, Andrea Gsur, Marc J. Gunter, Michael Hoffmeister, Li Hsu, Wen-Yi Huang, Paul Limburg, JoAnn E. Manson, Victor Moreno, Rami Nassir, Jonathan A. Nowak, Mireia Obón-Santacana, Shuji Ogino, Amanda I. Phipps, John D. Potter, Robert E. Schoen, Wei Sun, Amanda E. Toland, Quang M. Trinh, Tomotaka Ugai, Finlay A. Macrae, Christophe Rosty, Thomas J. Hudson, Mark A. Jenkins, Stephen N. Thibodeau, Ingrid M. Winship, Ulrike Peters, Daniel D. Buchanan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Germline biallelic pathogenic MUTYH variants predispose patients to colorectal cancer (CRC); however, approaches to identify MUTYH variant carriers are lacking. Here, the authors evaluated mutational signatures that could distinguish MUTYH carriers i
Externí odkaz:
https://doaj.org/article/333b1f57f922432c8d0bf0c51f25cb70
Autor:
David A. Drew, MD, MS
Publikováno v:
Kidney Medicine, Vol 5, Iss 3, Pp 100609- (2023)
Externí odkaz:
https://doaj.org/article/c22069d615d746c99554d7d48bb92a30