Zobrazeno 1 - 10
of 1 026
pro vyhledávání: '"David A. Black"'
Publikováno v:
Molecules, Vol 29, Iss 17, p 4273 (2024)
Tetrahydroquinolines are key structures in a variety of natural products with diverse pharmacological utilities and other applications. A series of 3,4-diaryl-5,7-dimethoxy-1,2,3,4-tetrahydroquinolines were synthesized in good yield by reacting 3-ary
Externí odkaz:
https://doaj.org/article/0e4d69aa9eed49a3bec7295195ab34f3
Autor:
Vina R. Aldilla, Renxun Chen, Rajesh Kuppusamy, Sudip Chakraborty, Mark D. P. Willcox, David StC. Black, Pall Thordarson, Adam D. Martin, Naresh Kumar
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract In this study, we prepared antibacterial hydrogels through the self-assembly of naphthyl anthranilamide (NaA) capped amino acid based cationic peptide mimics. These ultra-short cationic peptide mimics were rationally designed with NaA as a c
Externí odkaz:
https://doaj.org/article/739cf1fdba564463a042d623a1edc1f9
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
BackgroundCurrent depression, anxiety, and suicide screening techniques rely on retrospective patient reported symptoms to standardized scales. A qualitative approach to screening combined with the innovation of natural language processing (NLP) and
Externí odkaz:
https://doaj.org/article/969e30ee335043779378db4eea892aa7
Publikováno v:
Molecules, Vol 29, Iss 1, p 166 (2023)
A synthetic pathway to a novel 4-aryl-3,4-dihydro-2H-1,4-benzoxazine scaffold was developed and a series of compounds based on the scaffold were synthesised as potential anticancer agents. The 4-aryl-substituted compounds were prepared via Buchwald
Externí odkaz:
https://doaj.org/article/cab612ed311441b0965de8c04a996d85
Publikováno v:
Antibiotics, Vol 12, Iss 7, p 1227 (2023)
As bacteria continue to develop resistance mechanisms against antimicrobials, an alternative method to tackle this global concern must be developed. As the pqs system is the most well-known and responsible for biofilm and pyocyanin production, quinaz
Externí odkaz:
https://doaj.org/article/dce45bf384e04a0998fb7e2cd3830c6f
Autor:
Daehun Kang, Myung-Ho In, Hang Joon Jo, Maria A. Halverson, Nolan K. Meyer, Zaki Ahmed, Erin M. Gray, Radhika Madhavan, Thomas K. Foo, Brice Fernandez, David F. Black, Kirk M. Welker, Joshua D. Trzasko, John Huston, Matt A. Bernstein, Yunhong Shu
Publikováno v:
Sensors, Vol 23, Iss 9, p 4329 (2023)
In blood-oxygen-level-dependent (BOLD)-based resting-state functional (RS-fMRI) studies, usage of multi-echo echo-planar-imaging (ME-EPI) is limited due to unacceptable late echo times when high spatial resolution is used. Equipped with high-performa
Externí odkaz:
https://doaj.org/article/4becf7eb82934a92a443dee7f7fbf71a
Autor:
Rajesh Kuppusamy, Muhammad Yasir, Tsz Tin Yu, Florida Voli, Orazio Vittorio, Michael J. Miller, Peter Lewis, David StC Black, Mark Willcox, Naresh Kumar
Publikováno v:
Antibiotics, Vol 12, Iss 3, p 585 (2023)
There is a pressing need to develop new antimicrobials to help combat the increase in antibiotic resistance that is occurring worldwide. In the current research, short amphiphilic antibacterial and antibiofilm agents were produced by tuning the hydro
Externí odkaz:
https://doaj.org/article/7e6a6aceea644ab5b17e529e28105b80
Autor:
Humberto H. Lara, David M. Black, Christine Moon, Elizabeth Orr, Priscilla Lopez, Marcos M. Alvarez, Glen Baghdasarian, Jose Lopez-Ribot, Robert L. Whetten
Publikováno v:
ACS Omega, Vol 4, Iss 26, Pp 21914-21920 (2019)
Externí odkaz:
https://doaj.org/article/7bc371dbd47e4f62bf5b18edb8326588
Autor:
Ghayah Bahatheg, Rajesh Kuppusamy, Muhammad Yasir, David StC. Black, Mark Willcox, Naresh Kumar
Publikováno v:
Antibiotics, Vol 11, Iss 8, p 1074 (2022)
Peptoids are peptidomimetics that have attracted considerable interest as a promising class of antimicrobials against multi-drug-resistant bacteria due to their resistance to proteolysis, bioavailability, and thermal stability compared to their corre
Externí odkaz:
https://doaj.org/article/bdfdc3c7c50445c2ac78c34f0b607def
Autor:
Basmah Almohaywi, Tsz Tin Yu, George Iskander, Shekh Sabir, Mohan Bhadbhade, David StC. Black, Naresh Kumar
Publikováno v:
Antibiotics, Vol 11, Iss 2, p 151 (2022)
The Quorum-sensing system in Pseudomonas aeruginosa is responsible for the pathogenicity and the production of virulence factors and biofilm formation. Dihydropyrrolones were previously found to act as inhibitors of QS-dependent bacterial phenotypes.
Externí odkaz:
https://doaj.org/article/f140969dd3564e1fb30a2eef0962d63a