Zobrazeno 1 - 10
of 12 820
pro vyhledávání: '"David A Williams"'
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0303500 (2024)
Untargeted metabolomics investigations have characterized metabolic disturbances associated with various diseases in domestic cats. However, the pre-analytic stability of serum metabolites in the species is unknown. Our objective was to compare serum
Externí odkaz:
https://doaj.org/article/191f4d4f9e2d4f3fb58cf199965585bf
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0294730 (2024)
Fresh-frozen stool banks intended for humans with gastrointestinal and metabolic disorders have been recently established and there are ongoing efforts to establish the first veterinary fresh-frozen stool bank. Fresh frozen stored feces provide an ad
Externí odkaz:
https://doaj.org/article/401adee1f73b4570bb7a25bb9e35adad
The rapid increase in resident space objects, including satellites and orbital debris, threatens the safety and sustainability of space missions. This paper explores orbital debris remediation using laser ablation with a network of collaborative spac
Externí odkaz:
http://arxiv.org/abs/2409.03146
Autor:
Nicole L Laia, Patrick C Barko, Drew R Sullivan, Maureen A McMichael, David A Williams, Jennifer M Reinhart
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0273792 (2022)
There have been numerous studies in humans and rodents substantiating the role of the gastrointestinal microbiome in the pathogenesis and progression of both type 1 and type 2 diabetes mellitus. Diabetes mellitus is a common endocrinopathy in dogs; h
Externí odkaz:
https://doaj.org/article/195e9b7f75244d58b410ec5cec164220
Autor:
Arnon Gal, Patrick C Barko, Patrick J Biggs, Kristene R Gedye, Anne C Midwinter, David A Williams, Richard K Burchell, Paolo Pazzi
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250344 (2021)
Canine acute hemorrhagic diarrhea syndrome (AHDS) has been associated in some studies with Clostridioides perfringens overgrowth and toxin-mediated necrosis of the intestinal mucosa. We aimed to determine the effect of a single fecal microbiota trans
Externí odkaz:
https://doaj.org/article/6ed2955577654b5f89cefbbc31b95670
Autor:
Patrick C Barko, David A Williams
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257856 (2021)
Exocrine pancreatic insufficiency (EPI) causes chronic digestive dysfunction in cats, but its pathogenesis and pathophysiology are poorly understood. Untargeted metabolomics is a promising analytic methodology that can reveal novel metabolic features
Externí odkaz:
https://doaj.org/article/988f9628fae1412fbdd8beaf037780b6
In this paper, we address the problem of reconfiguring Earth observation satellite constellation systems through multiple stages. The Multi-stage Constellation Reconfiguration Problem (MCRP) aims to maximize the total observation rewards obtained by
Externí odkaz:
http://arxiv.org/abs/2401.11567
Autor:
Liyen Katrina Kan, Katharine J Drummond, Martin Hunn, David A Williams, Terence J O’Brien, Mastura Monif
Publikováno v:
Methods and Protocols, Vol 3, Iss 1, p 11 (2020)
Glioblastoma is a heterogeneous glial cell malignancy with extremely high morbidity and mortality. Current treatment is limited and provide minimal therapeutic efficacy. Previous studies were reliant on cell lines that do not accurately reflect the h
Externí odkaz:
https://doaj.org/article/41fb981635be4f6ea03ac983a100af3b
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169974 (2017)
In this study, we investigated the relative efficacy of different classes of commonly used anti-epileptic drugs (AEDs) with different mechanisms of action, individually and in combination, to suppress epileptiform discharges in an in vitro model. Ext
Externí odkaz:
https://doaj.org/article/2571c981f9014295bd3bdc71980fbe07
Autor:
Serena De Vita, Rebekka K Schneider, Michael Garcia, Jenna Wood, Mathilde Gavillet, Benjamin L Ebert, Alexander Gerbaulet, Axel Roers, Ross L Levine, Ann Mullally, David A Williams
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96209 (2014)
Systemic Mastocytosis (SM) is a clonal disease characterized by abnormal accumulation of mast cells in multiple organs. Clinical presentations of the disease vary widely from indolent to aggressive forms, and to the exceedingly rare mast cell leukemi
Externí odkaz:
https://doaj.org/article/7857a9f7de7c4ea89650b596a89f3907