Zobrazeno 1 - 10
of 69
pro vyhledávání: '"David A Sarracino"'
Autor:
Scarlet S Shell, Jing Wang, Pascal Lapierre, Mushtaq Mir, Michael R Chase, Margaret M Pyle, Richa Gawande, Rushdy Ahmad, David A Sarracino, Thomas R Ioerger, Sarah M Fortune, Keith M Derbyshire, Joseph T Wade, Todd A Gray
Publikováno v:
PLoS Genetics, Vol 11, Iss 11, p e1005641 (2015)
RNA-seq technologies have provided significant insight into the transcription networks of mycobacteria. However, such studies provide no definitive information on the translational landscape. Here, we use a combination of high-throughput transcriptom
Externí odkaz:
https://doaj.org/article/cc14b07582f341739c4a970a97445956
Autor:
Laura A Huppert, Talia L Ramsdell, Michael R Chase, David A Sarracino, Sarah M Fortune, Briana M Burton
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96267 (2014)
Esat-6 protein secretion systems (ESX or Ess) are required for the virulence of several human pathogens, most notably Mycobacterium tuberculosis and Staphylococcus aureus. These secretion systems are defined by a conserved FtsK/SpoIIIE family ATPase
Externí odkaz:
https://doaj.org/article/3b134238bba8426eb07c169c67ab70af
Autor:
Alaullah Sheikh, Farhana Khanam, Md Abu Sayeed, Taibur Rahman, Marcin Pacek, Yanhui Hu, Andrea Rollins, Md Saruar Bhuiyan, Sean Rollins, Anuj Kalsy, Mohammad Arifuzzaman, Daniel T Leung, David A Sarracino, Bryan Krastins, Richelle C Charles, Regina C Larocque, Alejandro Cravioto, Stephen B Calderwood, W Abdullah Brooks, Jason B Harris, Joshua Labaer, Firdausi Qadri, Edward T Ryan
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 6, p e1193 (2011)
Salmonella enterica serotype Typhi is a human-restricted intracellular pathogen and the cause of typhoid fever. Cellular immune responses are required to control and clear Salmonella infection. Despite this, there are limited data on cellular immune
Externí odkaz:
https://doaj.org/article/2a79d07a6ec9406c813033ac245c67f9
Autor:
Alejandra Garces, Krishnamohan Atmakuri, Michael R Chase, Joshua S Woodworth, Bryan Krastins, Alissa C Rothchild, Talia L Ramsdell, Mary F Lopez, Samuel M Behar, David A Sarracino, Sarah M Fortune
Publikováno v:
PLoS Pathogens, Vol 6, Iss 6, p e1000957 (2010)
Mycobacterium tuberculosis (Mtb) requires the ESX1 specialized protein secretion system for virulence, for triggering cytosolic immune surveillance pathways, and for priming an optimal CD8+ T cell response. This suggests that ESX1 might act primarily
Externí odkaz:
https://doaj.org/article/3c82ff02706441dd92e9f52dda4a3d32
Autor:
Richelle C Charles, Jason B Harris, Michael R Chase, Lauren M Lebrun, Alaullah Sheikh, Regina C LaRocque, Tanya Logvinenko, Sean M Rollins, Abdullah Tarique, Elizabeth L Hohmann, Ian Rosenberg, Bryan Krastins, David A Sarracino, Firdausi Qadri, Stephen B Calderwood, Edward T Ryan
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e6994 (2009)
BACKGROUND:S. Typhi, a human-restricted Salmonella enterica serovar, causes a systemic intracellular infection in humans (typhoid fever). In comparison, S. Typhimurium causes gastroenteritis in humans, but causes a systemic typhoidal illness in mice.
Externí odkaz:
https://doaj.org/article/f8eb8ec01b4548b59bd1e0c614d5625e
Autor:
David A. Sarracino, Zhen Zhang, Khalid Malik, Kathryn J. Gray, Hooman Mirzakhani, Brohman Brian D, David E. Cantonwine, Thomas F. McElrath, Gail Page, Robert C. Doss, Khaja Najmuddin, Kevin P. Rosenblatt
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
We hypothesize that first trimester circulating micro particle (CMP) proteins will define preeclampsia risk while identifying clusters of disease subtypes among cases. We performed a nested case–control analysis among women with and without preecla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01565c5f08ba2169792e75cc552315f3
http://link.springer.com/article/10.1038/s41598-020-74078-w
http://link.springer.com/article/10.1038/s41598-020-74078-w
Autor:
Peter Angelos, Edwin L. Kaplan, David A. Sarracino, Raymon H. Grogan, Bryan Krastins, Edward Ki Yun Leung, Christine C. Lee, Kiang-Teck J. Yeo, Mary F. Lopez, Theodore Karrison
Publikováno v:
The journal of applied laboratory medicine. 3(5)
Background We compared the rates of intraoperative parathyroid hormone (PTH) decline using the Siemens Immulite® Turbo PTH and Roche Elecsys® short turnaround time PTH assays in 95 consecutive surgical patients to investigate analytical and turnaro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a07056cd672b013def3e31c0d63f51e
https://pubmed.ncbi.nlm.nih.gov/31639754
https://pubmed.ncbi.nlm.nih.gov/31639754
Autor:
Robert W. Griffin, Carolyn J. Hovde, Manohar John, Alfredo G. Torres, Stephen B. Calderwood, David A. Sarracino, Indira T. Kudva, Bryan Krastins, Haiqing Sheng
Publikováno v:
PROTEOMICS. 15:1829-1842
Building on previous studies, we defined the repertoire of proteins comprising the immunoproteome (IP) of Escherichia coli O157:H7 (O157) cultured in DMEM supplemented with norepinephrine (O157 IP), a β-adrenergic hormone that regulates E. coli O157
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f1da6dd69c3961fdcedd08f1ca58c4
https://doi.org/10.1002/pmic.201400432
https://doi.org/10.1002/pmic.201400432
Publikováno v:
Cancer Research. 79:2225-2225
Introduction: Exosomes have been used as a source of biomarkers in diagnostics for many diseases, including cancer, and are now being used as therapeutic delivery systems. To date, the most efficient method for isolating exosomes from serum or plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1566c616601a9cfbf12df4717f3ea86
https://doi.org/10.1158/1538-7445.am2019-2225
https://doi.org/10.1158/1538-7445.am2019-2225
Autor:
Reuben Gobezie, Thomas Aigner, David A. Sarracino, Mary K. Crow, Antonios O. Aliprantis, Bryan Krastins, Steven R. Goldring, David M. Lee, Carla R. Scanzello, Susan Y. Ritter, Roopashree Subbaiah, Gurkan Bebek, Mary F. Lopez, James F. Crish, Mary B. Goldring
Publikováno v:
Arthritis & Rheumatism. 65:981-992
Objective The pathophysiology of the most common joint disease, osteoarthritis (OA), remains poorly understood. Since synovial fluid (SF) bathes joint cartilage and synovium, we reasoned that a comparative analysis of its protein constituents in heal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbe2d9df99f3535dc21a238ab20dccb1
https://doi.org/10.1002/art.37823
https://doi.org/10.1002/art.37823