Zobrazeno 1 - 10
of 70
pro vyhledávání: '"David A Prober"'
Autor:
Ida L Barlow, Eirinn Mackay, Emily Wheater, Aimee Goel, Sumi Lim, Steve Zimmerman, Ian Woods, David A Prober, Jason Rihel
Publikováno v:
eLife, Vol 12 (2023)
Sleep is a nearly universal feature of animal behaviour, yet many of the molecular, genetic, and neuronal substrates that orchestrate sleep/wake transitions lie undiscovered. Employing a viral insertion sleep screen in larval zebrafish, we identified
Externí odkaz:
https://doaj.org/article/221b77ce3f6641329cfae8555a7e436b
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0278316 (2023)
With the oncoming age of big data, biologists are encountering more use cases for cloud-based computing to streamline data processing and storage. Unfortunately, cloud platforms are difficult to learn, and there are few resources for biologists to de
Externí odkaz:
https://doaj.org/article/260320f323274ddd8f6d0c5966e76627
Autor:
Daniel A Lee, Grigorios Oikonomou, Tasha Cammidge, Andrey Andreev, Young Hong, Hannah Hurley, David A Prober
Publikováno v:
eLife, Vol 9 (2020)
Although several sleep-regulating neuronal populations have been identified, little is known about how they interact with each other to control sleep/wake states. We previously identified neuropeptide VF (NPVF) and the hypothalamic neurons that produ
Externí odkaz:
https://doaj.org/article/1da4463f70814243832062af15bb4ae7
Publikováno v:
eLife, Vol 7 (2018)
The duration of sleep varies dramatically between species, yet little is known about the genetic basis or evolutionary factors driving this variation in behavior. The Mexican cavefish, Astyanax mexicanus, exists as surface populations that inhabit ri
Externí odkaz:
https://doaj.org/article/9d29ad01f2654beb8ec3bfc61736bd98
Autor:
Daniel A Lee, Andrey Andreev, Thai V Truong, Audrey Chen, Andrew J Hill, Grigorios Oikonomou, Uyen Pham, Young K Hong, Steven Tran, Laura Glass, Viveca Sapin, Jae Engle, Scott E Fraser, David A Prober
Publikováno v:
eLife, Vol 6 (2017)
Sleep is an essential and phylogenetically conserved behavioral state, but it remains unclear to what extent genes identified in invertebrates also regulate vertebrate sleep. RFamide-related neuropeptides have been shown to promote invertebrate sleep
Externí odkaz:
https://doaj.org/article/bb3eedc1ac6e49f59dd3f86039a73d4b
Publikováno v:
eLife, Vol 4 (2015)
Pharmacological studies in mammals suggest that norepinephrine (NE) plays an important role in promoting arousal. However, the role of endogenous NE is unclear, with contradicting reports concerning the sleep phenotypes of mice lacking NE due to muta
Externí odkaz:
https://doaj.org/article/4a947489be95487185e0d41cb4527aee
Autor:
Cindy N Chiu, David A Prober
Publikováno v:
Frontiers in Neural Circuits, Vol 7 (2013)
Every day, we shift among various states of sleep and arousal to meet the many demands of our bodies and environment. A central puzzle in neurobiology is how the brain controls these behavioral states, which are essential to an animal’s well-being
Externí odkaz:
https://doaj.org/article/4846dcd8c75c4be7a25337be2444c6db
Autor:
Ivan Bassi, Francesca Luzzani, Federica Marelli, Valeria Vezzoli, Ludovica Cotellessa, David A. Prober, Luca Persani, Yoav Gothilf, Marco Bonomi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract Prokineticin receptors (PROKR1 and PROKR2) are G protein-coupled receptors which control human central and peripheral reproductive processes. Importantly, allelic variants of PROKR2 in humans are associated with altered migration of GnRH neu
Externí odkaz:
https://doaj.org/article/a5f5f89f259a47f8945dc2ba1d98ee2d
Autor:
Ida L. Barlow, Eirinn Mackay, Emily Wheater, Aimee Goel, Sumi Lim, Steve Zimmerman, Ian Woods, David A. Prober, Jason Rihel
Sleep is a nearly universal feature of animal behaviour, yet many of the molecular, genetic, and neuronal substrates that orchestrate sleep/wake transitions lie undiscovered. Employing a viral insertion sleep screen in larval zebrafish, we identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ab0d27302f236a39c0b55ca494439b
https://doi.org/10.7554/elife.87521.1
https://doi.org/10.7554/elife.87521.1
Autor:
Mahendra Wagle, Mahdi Zarei, Matthew Lovett-Barron, Kristina Tyler Poston, Jin Xu, Vince Ramey, Katherine S. Pollard, David A. Prober, Jay Schulkin, Karl Deisseroth, Su Guo
Publikováno v:
Molecular psychiatry, vol 27, iss 9
Salient sensory stimuli are perceived by the brain, which guides both the timing and outcome of behaviors in a context-dependent manner. Light is such a stimulus, which is used in treating mood disorders often associated with a dysregulated hypothala