Anti-platelet therapy with clopidogrel prevents endothelial dysfunction and vascular remodeling in aortas from hypertensive rats.

Autor: Fernanda R Giachini, Romulo Leite, David A Osmond, Victor V Lima, Edward W Inscho, R Clinton Webb, Rita C Tostes

Publikováno v: PLoS ONE, Vol 9, Iss 3, p e91890 (2014)

The aim was to investigate the beneficial effects of clopidogrel in thoracic aorta function and structure and to characterize if P2Y12 receptors contribute to these effects. Male Sprague Dawley rats were infused with angiotensin II [(Ang II) 60 ng x

Externí odkaz: https://doaj.org/article/38ed0d193bf8449fb3b5f02ae665cb11

Role of ASIC1 in the development of chronic hypoxia-induced pulmonary hypertension

Autor: Lindsay M. Herbert, Carlos H. Nitta, David A. Osmond, Nikki L. Jernigan, Britta F. Beasley, Benjimen R. Walker, Thomas C. Resta

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 306:H41-H52

Chronic hypoxia (CH) associated with respiratory disease results in elevated pulmonary vascular intracellular Ca2+ concentration, which elicits enhanced vasoconstriction and promotes vascular arterial remodeling and thus has important implications in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f297a93d8a6260923ee665c4aa0457
https://doi.org/10.1152/ajpheart.00269.2013

P2X1receptor blockade inhibits whole kidney autoregulation of renal blood flow in vivo

Autor: Edward W. Inscho, David A. Osmond

Publikováno v: American Journal of Physiology-Renal Physiology. 298:F1360-F1368

In vitro experiments demonstrate that P2X1receptor activation is important for normal afferent arteriolar autoregulatory behavior, but direct in vivo evidence for this relationship occurring in the whole kidney is unavailable. Experiments were perfor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a46a52ba8b7aea389a804885f30e7468
https://doi.org/10.1152/ajprenal.00016.2010

Anti-platelet therapy with clopidogrel prevents endothelial dysfunction and vascular remodeling in aortas from hypertensive rats

Autor: Victor V. Lima, David A. Osmond, R. Clinton Webb, Rita de Cássia Tostes, Edward W. Inscho, Romulo Leite, Fernanda R. Giachini

Publikováno v: PLoS ONE, Vol 9, Iss 3, p e91890 (2014)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da UFOP
Universidade Federal de Ouro Preto (UFOP)
instacron:UFOP
PLoS ONE

The aim was to investigate the beneficial effects of clopidogrel in thoracic aorta function and structure and to characterize if P2Y12 receptors contribute to these effects. Male Sprague Dawley rats were infused with angiotensin II [(Ang II) 60 ng x

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b4913fa791f1b3e664f0f82260fd91
http://europepmc.org/articles/PMC3956760?pdf=render

Tetrazole ethers from lignin model phenols: synthesis, crystal structures, and photostability

Autor: Brian R. James, David A. Osmond, Thomas Q. Hu, Brian O. Patrick, Andy Z. Lu

Publikováno v: Canadian Journal of Chemistry. 79:1201-1206

The phenolic OH moiety in lignin is one of the key functional groups responsible for the photo-induced yellowing of mechanical wood pulps and papers. To evaluate new protective groups for the stabilization of lignin phenols, the model compounds, 2-me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::03b3300254a0d849a22177f4eaade3e9
https://doi.org/10.1139/v01-110