Zobrazeno 1 - 10
of 15
pro vyhledávání: '"David A Leinster"'
Autor:
Nadia Luheshi, Joshua P. Frederick, Ronald Herbst, Robert W. Wilkinson, Maja Sedic, Chris Morehouse, Han Si, Jean-Martin Lapointe, Philip Martin, Chris Bagnall, Michal Sulikowski, Steve Novick, David A. Leinster, Gordon Moody, Darren Potz, Katharina Deschler, Grace Adjei, Kathy Mulgrew, Eleanor Clancy-Thompson, James Moynihan, Kristen Arnold, Amanda Watkins, Sushma Gurumurthy, Ankita Mishra, Fabien Garcon, Shannon Burke, Russell Karp, Faith Musenge, Ameya Apte, John Zielinski, Dyane Bailey, Susannah L. Hewitt
Supplementary Figures S1-S11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::447a2faa43430fbac4574cf80676b109
https://doi.org/10.1158/1078-0432.22477526
https://doi.org/10.1158/1078-0432.22477526
Autor:
Ross Stewart, Robert W. Wilkinson, Ching Ching Leow, Athula Herath, Philip Mallinder, Scott A. Hammond, Michelle Morrow, Lesley Young, Kelly McGlinchey, David A. Leinster, Jane Coates Ulrichsen, Michael D. Oberst, Stefanie Mullins, Li Yan, John Andrews, Emily Offer, Natalie J. Tigue, Lisa Bamber, Nicholas Holoweckyj, Kathy A. Mulgrew, Amanda Watkins, Rebecca Leyland
Additional materials and methods and supplementary figure legends with tracked changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::671e099e5f25fb580caea686b8b7f676
https://doi.org/10.1158/1078-0432.22463777.v1
https://doi.org/10.1158/1078-0432.22463777.v1
Autor:
Nadia Luheshi, Joshua P. Frederick, Ronald Herbst, Robert W. Wilkinson, Maja Sedic, Chris Morehouse, Han Si, Jean-Martin Lapointe, Philip Martin, Chris Bagnall, Michal Sulikowski, Steve Novick, David A. Leinster, Gordon Moody, Darren Potz, Katharina Deschler, Grace Adjei, Kathy Mulgrew, Eleanor Clancy-Thompson, James Moynihan, Kristen Arnold, Amanda Watkins, Sushma Gurumurthy, Ankita Mishra, Fabien Garcon, Shannon Burke, Russell Karp, Faith Musenge, Ameya Apte, John Zielinski, Dyane Bailey, Susannah L. Hewitt
Purpose:While immune checkpoint inhibitors such as anti–PD-L1 are rapidly becoming the standard of care in the treatment of many cancers, only a subset of treated patients have long-term responses. IL12 promotes antitumor immunity in mouse models;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b977133483ab014e3abfe875a2074603
https://doi.org/10.1158/1078-0432.c.6529685
https://doi.org/10.1158/1078-0432.c.6529685
Autor:
Ross Stewart, Robert W. Wilkinson, Ching Ching Leow, Athula Herath, Philip Mallinder, Scott A. Hammond, Michelle Morrow, Lesley Young, Kelly McGlinchey, David A. Leinster, Jane Coates Ulrichsen, Michael D. Oberst, Stefanie Mullins, Li Yan, John Andrews, Emily Offer, Natalie J. Tigue, Lisa Bamber, Nicholas Holoweckyj, Kathy A. Mulgrew, Amanda Watkins, Rebecca Leyland
Supplementary figures S1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697d83739c7675c2a3405246bc4a4539
https://doi.org/10.1158/1078-0432.22463783.v1
https://doi.org/10.1158/1078-0432.22463783.v1
Autor:
Nadia Luheshi, Joshua P. Frederick, Ronald Herbst, Robert W. Wilkinson, Maja Sedic, Chris Morehouse, Han Si, Jean-Martin Lapointe, Philip Martin, Chris Bagnall, Michal Sulikowski, Steve Novick, David A. Leinster, Gordon Moody, Darren Potz, Katharina Deschler, Grace Adjei, Kathy Mulgrew, Eleanor Clancy-Thompson, James Moynihan, Kristen Arnold, Amanda Watkins, Sushma Gurumurthy, Ankita Mishra, Fabien Garcon, Shannon Burke, Russell Karp, Faith Musenge, Ameya Apte, John Zielinski, Dyane Bailey, Susannah L. Hewitt
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e329b32ceccaccb01d825f32846ab6
https://doi.org/10.1158/1078-0432.22477523
https://doi.org/10.1158/1078-0432.22477523
Autor:
Ross Stewart, Robert W. Wilkinson, Ching Ching Leow, Athula Herath, Philip Mallinder, Scott A. Hammond, Michelle Morrow, Lesley Young, Kelly McGlinchey, David A. Leinster, Jane Coates Ulrichsen, Michael D. Oberst, Stefanie Mullins, Li Yan, John Andrews, Emily Offer, Natalie J. Tigue, Lisa Bamber, Nicholas Holoweckyj, Kathy A. Mulgrew, Amanda Watkins, Rebecca Leyland
Purpose: To generate and characterize a murine GITR ligand fusion protein (mGITRL-FP) designed to maximize valency and the potential to agonize the GITR receptor for cancer immunotherapy.Experimental Design: The EC50 value of the mGITRL-FP was compar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7e495d8f0b024911cdaaba2097a9fc
https://doi.org/10.1158/1078-0432.c.6525515
https://doi.org/10.1158/1078-0432.c.6525515
Autor:
Ross Stewart, Robert W. Wilkinson, Ching Ching Leow, Athula Herath, Philip Mallinder, Scott A. Hammond, Michelle Morrow, Lesley Young, Kelly McGlinchey, David A. Leinster, Jane Coates Ulrichsen, Michael D. Oberst, Stefanie Mullins, Li Yan, John Andrews, Emily Offer, Natalie J. Tigue, Lisa Bamber, Nicholas Holoweckyj, Kathy A. Mulgrew, Amanda Watkins, Rebecca Leyland
Additional materials and methods and supplementary figure legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d03ee0abf1e2c2c527f5f5b6e61da07
https://doi.org/10.1158/1078-0432.22463780.v1
https://doi.org/10.1158/1078-0432.22463780.v1
Autor:
Frances Balkwill, James R. Whiteford, Richard Thompson, Robert E. Hollingsworth, Haihong Zhong, David A. Leinster, Kairbaan Hodivala-Dilke, Louise E. Reynolds, Oliver M.T. Pearce, Carla Milagre, Ganga Gopinathan
Supplementary Figures S1-S7. Western blot quantification of pERK and pSTAT3 from aortic lysates (S1); Western blot quantification of pERK and pSTAT3 from MLEC lysates (S2); Western blot analysis and quantification of pERK and pSTAT3 from HUVEC lysate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f1652258a02215fcd0f142e8883b3e
https://doi.org/10.1158/0008-5472.22405032.v1
https://doi.org/10.1158/0008-5472.22405032.v1
Autor:
Frances Balkwill, James R. Whiteford, Richard Thompson, Robert E. Hollingsworth, Haihong Zhong, David A. Leinster, Kairbaan Hodivala-Dilke, Louise E. Reynolds, Oliver M.T. Pearce, Carla Milagre, Ganga Gopinathan
Legend for Supplementary Figures S1-S7.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47659289113ba6140c957d0a6e7c3496
https://doi.org/10.1158/0008-5472.22405035.v1
https://doi.org/10.1158/0008-5472.22405035.v1
Autor:
Kristen Arnold, Chris Morehouse, Eleanor Clancy-Thompson, Katharina Deschler, Susannah Hewitt, Russell Karp, Ameya Apte, Chris Bagnall, Faith Musenge, Darren Potz, David A. Leinster, Kathy Mulgrew, Ankita Mishra, Gordon Moody, Maja Sedic, Joshua Frederick, John Zielinski, Fabien Garcon, Sushma Gurumurthy, Nadia Luheshi, Michal Sulikowski, Steve Novick, Han Si, Philip Martin, Grace Adjei, James Moynihan, Jean-Martin Lapointe, Amanda Watkins, Shannon Burke, Ronald Herbst, Dyane Bailey, Robert W. Wilkinson
Publikováno v:
Clinical Cancer Research. 26:6284-6298
Purpose: While immune checkpoint inhibitors such as anti–PD-L1 are rapidly becoming the standard of care in the treatment of many cancers, only a subset of treated patients have long-term responses. IL12 promotes antitumor immunity in mouse models;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5aa76c833838d68d2852862e2fa941
https://doi.org/10.1158/1078-0432.ccr-20-0472
https://doi.org/10.1158/1078-0432.ccr-20-0472
