Zobrazeno 1 - 10
of 4 074
pro vyhledávání: '"David A Lee"'
Publikováno v:
Journal of Medical Internet Research, Vol 26, p e52401 (2024)
BackgroundWe queried ChatGPT (OpenAI) and Google Assistant about amblyopia and compared their answers with the keywords found on the American Association for Pediatric Ophthalmology and Strabismus (AAPOS) website, specifically the section on amblyopi
Externí odkaz:
https://doaj.org/article/cc4ff9ef9e3649d28d70d818d2365f36
Publikováno v:
Digital Health, Vol 10 (2024)
Objectives “Floaters,” a common complaint among patients of all ages, was used as a query term because it affects 30% of all people searching for eye care. The American Academy of Ophthalmology website's “floaters” section was used as a sourc
Externí odkaz:
https://doaj.org/article/0bda729087fb4f7a819dc8447d8dd17e
Autor:
Su-Jin Heo, Tristan P Driscoll, Stephen D Thorpe, Nandan L Nerurkar, Brendon M Baker, Michael T Yang, Christopher S Chen, David A Lee, Robert L Mauck
Publikováno v:
eLife, Vol 5 (2016)
Mesenchymal stem cell (MSC) differentiation is mediated by soluble and physical cues. In this study, we investigated differentiation-induced transformations in MSC cellular and nuclear biophysical properties and queried their role in mechanosensation
Externí odkaz:
https://doaj.org/article/16c1483368c14410ae3abebcf88a3596
Autor:
David E. Lee, Lauren K. McKay, Akshay Bareja, Yongwu Li, Alastair Khodabukus, Nenad Bursac, Gregory A. Taylor, Gurpreet S. Baht, James P. White
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Lee et al. demonstrate the protein Meteorin-like can rejuvenate the body’s immune system to enhance muscle regeneration in old age – in part by inducing the death of pro-fibrotic mesenchymal progenitor cells within the muscle.
Externí odkaz:
https://doaj.org/article/8fcfebcc8c834ce3ab90df115f69407e
Autor:
Daniela Rodrigues Recchia, Holger Cramer, Jon Wardle, David J. Lee, Thomas Ostermann, Romy Lauche
Publikováno v:
BMC Health Services Research, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Introduction The identification of typologies of health care users and their specific characteristics can be performed using cluster analysis. This statistical approach aggregates similar users based on their common health-related behavior.
Externí odkaz:
https://doaj.org/article/394f28297e174874a0584cc67ea042ba
Autor:
Massimo Martinelli, Gabrielle Aguilar, David S.M. Lee, Andrew Kromer, Nhu Nguyen, Benjamin J. Wilkins, Tatiana Akimova, Ulf H. Beier, Louis R. Ghanem
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105860- (2023)
Summary: The RNA-binding protein Pcbp2 is widely expressed in the innate and adaptive immune systems and is essential for mouse development. To determine whether Pcbp2 is required for CD4+ T cell development and function, we derived mice with conditi
Externí odkaz:
https://doaj.org/article/abe9b38a417741fba48e88fa11136c14
Autor:
Megan E. Rosa‐Caldwell, Seongkyun Lim, Wesley S. Haynie, Jacob L. Brown, David E. Lee, Kirsten R. Dunlap, Lisa T. Jansen, Tyrone A. Washington, Michael P. Wiggs, Nicholas P. Greene
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 6, Pp 2056-2068 (2021)
Abstract Background Disuse decreases muscle size and is predictive of mortality across multiple pathologies. Detriments to mitochondrial function are hypothesized to underlie disuse‐induced muscle atrophy. Little data exist on early mechanisms cont
Externí odkaz:
https://doaj.org/article/c078e7da58e44ab58e7d90e1f6efbd14
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
This study examined the role of sirtuins in the regenerative potential of articular chondrocytes. Sirtuins (SIRT1-7) play a key role in regulating cartilage homeostasis. By inhibiting pro-inflammatory pathways responsible for cartilage degradation an
Externí odkaz:
https://doaj.org/article/1f8abf52476c450fad6b15c49082e7d8
Autor:
Isaac E. Kim, Thomas L. Jang, Sinae Kim, David Y. Lee, Daniel D. Kim, Eric A. Singer, Saum Ghodoussipour, Mark N. Stein, Monish Aron, Marc A. Dall’Era, Isaac Yi Kim
Publikováno v:
Cancer Medicine, Vol 10, Iss 22, Pp 7909-7920 (2021)
Abstract Since 2004, multiple blockbuster drugs have been approved for men with metastatic prostate cancer. Nevertheless, it has been reported that no improvement in survival was observed between 2004 and 2009. Herein, we have analyzed the SEER datab
Externí odkaz:
https://doaj.org/article/f0308822a4d1411cbcaa1149414a27a7
Autor:
Jennifer Coto, Carmen L. Alvarez, Ivette Cejas, Brett M. Colbert, Bonnie E. Levin, Joshua Huppert, Tatjana Rundek, Carey Balaban, Susan H. Blanton, David J. Lee, David Loewenstein, Michael Hoffer, Xue Zhong Liu
Publikováno v:
Journal of Otology, Vol 16, Iss 4, Pp 258-265 (2021)
Given the interdependence of multiple factors in age-related vestibular loss (e.g., balance, vision, cognition), it is important to examine the individual contributions of these factors with ARVL. While the relationship between the vestibular and vis
Externí odkaz:
https://doaj.org/article/18ff8995579e44549f9c8d6d536450c5