Zobrazeno 1 - 10
of 19
pro vyhledávání: '"David A J Stevenson"'
Autor:
Stephen Falk, Susan J Dutton, Wasat Mansoor, David A J Stevenson, Caroline Clark, Russell D. Petty, Aileen Osborne, Asa Dahle-Smith, Angel Garcia-Alonso, Mark Harrison, Joyce Thompson, Graeme I. Murray, Ian Chau, Irene Chong, Jonathan Wadsley, Corran Roberts, Doreen Massie, Zosia Miedzybrodzka, Anirban Chatterjee, Sean Elyan, David Walter Fyfe, David Ferry
Publikováno v:
Journal of Clinical Oncology. 35:2279-2287
Purpose The Cancer Esophagus Gefitinib trial demonstrated improved progression-free survival with the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib relative to placebo in patients with advanced esophageal cancer who had
Publikováno v:
Cancer Genetics. 205:599-602
The 3q21q26 inversion is associated with both myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), often in association with monosomy 7. In this report, we present a young woman and her mother, both diagnosed with AML, exhibiting similar
Autor:
Graeme I. Murray, David Ferry, Asa Dahle-Smith, David A J Stevenson, Zosia Miedzybrodzka, Doreen Massie, Corran Roberts, Susan J. Dutton, Caroline Clark, Aileen Osborne, Russell D. Petty
Publikováno v:
Molecular Cytogenetics
Background Clinical trials of agents targeting epidermal growth factor receptor (EGFR) in esophageal carcinoma (EC) have indicated a minority subgroup responsive to anti-EGFR therapies. Other investigations suggest increases in EGFR copy number are a
Autor:
Stephanie Curran, Neva E. Haites, David A J Stevenson, Graeme I. Murray, J A McKay, Patrick H. Rooney, Jim Cassidy, Sharon Marsh, Attasit Boonsong, Howard L. McLeod
Publikováno v:
British Journal of Cancer
Colorectal cancer (CRC) is a leading cause of cancer death and the mechanism for variable outcome in this disease is not yet fully understood. It is hypothesized that differences in the genetic make-up of tumours may be partially responsible for the
Autor:
Patrick H. Rooney, Jim Cassidy, Attasit Boonsong, Howard L. McLeod, Sharon Marsh, David A J Stevenson
Publikováno v:
Cancer Genetics and Cytogenetics. 121:56-60
DNA topoisomerase I (topo I) is the principle target for Camptothecin and its analogues. The topo I gene is located on chromosome 20q11.2-q13.1 and variation in topo I gene copy number has been shown to have impact on the in vitro sensitivity to topo
Autor:
Patrick H. Rooney, David A J Stevenson, J. Cassidy, Graeme I. Murray, Neva E. Haites, Howard L. McLeod
Publikováno v:
British Journal of Cancer
Autor:
Deepthi De Silva, John Dean, Thelma Brown, David A J Stevenson, Denys N. Wheatley, Richard Herriot, Peter Joseph Benedict Helms
Publikováno v:
American Journal of Medical Genetics. 69:56-64
We report the seventh case of Mulvihill-Smith progeria-like syndrome in a 5-year-old boy with a thin, pinched face, failure to thrive, and cutaneous pigmented nevi. The patient's motor and intellectual development were normal. His immune function tes
Autor:
David A J Stevenson, Neva E. Haites, Caroline Clark, Morag F. Wright, John D. Holmes, John Dean, Malcolm G. Dunlop, Elizabeth S. Gray, Deepthi De Silva
Publikováno v:
Cancer. 77:972-976
Background Familial adenomatous polyposis (FAP) is a dominantly inherited disorder characterized by the presence of more than 100 adenomatous polyps in the colon and rectum starting in the second decade of life. FAP is associated with extra colonic m
Autor:
Andrew Craig Schofield, Andrew W. Hutcheon, Neva Elizabeth Haites, David A J Stevenson, Sarah McDonald, Steven D. Heys, Susan Emma Moir
Publikováno v:
European journal of cancer (Oxford, England : 1990). 41(7)
Docetaxel is one of the most effective chemotherapeutic agents in the treatment of breast cancer. Breast cancers can have an inherent or acquired resistance to docetaxel but the causes of this resistance remain unclear. In this study high-level, doce
Autor:
David A J Stevenson, Emma Parsons, Michael J. Dyson, Jane Tighe, Polly Talley, John T. Reilly
Publikováno v:
Cancer genetics and cytogenetics. 147(1)
Involvement of the MLL gene located at chromosome region 11q23 is a frequent occurrence in both acute myelocytic leukemia and acute lymphoblastic leukemia. More than 30 loci have now been associated with MLL, usually by reciprocal translocation. Dele