Zobrazeno 1 - 10
of 149
pro vyhledávání: '"David A Hildeman"'
Autor:
Richard Furie, Joel M Guthridge, Judith A James, Maria Dall’Era, Michelle A Petri, Chaim Putterman, Jill P Buyon, Diane L Kamen, Betty Diamond, David Wofsy, Soumya Raychaudhuri, Thomas Tuschl, Jennifer Grossman, Peter M Izmirly, Qian Xiao, Nir Hacohen, Kenneth C Kalunian, Michael B Brenner, Mariko Ishimori, H Michael Belmont, Robert Clancy, ANNE DAVIDSON, Matthias Kretzler, Michael Weisman, Celine C Berthier, Andrea Fava, Jennifer L Barnas, Jennifer H Anolik, Paul J Hoover, Deepak A Rao, Arnon Arazi, William Apruzzese, Fernanda Payan-Schober, Joseph Mears, Saori Sakaue, James Lederer, Michael Peters, Tony Jones, Thomas M Eisenhaure, Siddarth Gurajala, Derek Fine, David A Hildeman, Steve Woodle, Maureen A McMahon, Jeffery Hodgin
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)
Externí odkaz:
https://doaj.org/article/65b7bcfbd80b4d188bbcb8ba5050d6cc
Autor:
Richard Furie, Joel M Guthridge, Judith A James, Maria Dall’Era, Michelle A Petri, Chaim Putterman, Jill P Buyon, Diane L Kamen, Betty Diamond, David Wofsy, Soumya Raychaudhuri, Thomas Tuschl, Jennifer Grossman, Peter M Izmirly, Qian Xiao, Nir Hacohen, Kenneth C Kalunian, Michael B Brenner, Mariko Ishimori, H Michael Belmont, Robert Clancy, ANNE DAVIDSON, Matthias Kretzler, Michael Weisman, Celine C Berthier, Andrea Fava, Jennifer L Barnas, Jennifer H Anolik, Paul J Hoover, Deepak A Rao, Arnon Arazi, William Apruzzese, Fernanda Payan-Schober, Saori Sakaue, James Lederer, Michael Peters, Tony Jones, Jospeh Mears, Thomas M Eisenhaure, Siddarth Gurajala, Derek Fine, David A Hildeman, Steve Woodle, Maureen A McMahon, Jeffery Hodgin
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss Suppl 3 (2022)
Externí odkaz:
https://doaj.org/article/1ff32e9bfffe45e7a30cc6f3a475aa6c
Autor:
Greg Davis, Allen J York, Willis Clark Bacon, Suh-Chin Lin, Monica Malone McNeal, Alexander E Yarawsky, Joseph J Maciag, Jeanette L C Miller, Kathryn C S Locker, Michelle Bailey, Rebecca Stone, Michael Hall, Judith Gonzalez, Alyssa Sproles, E Steve Woodle, Kristen Safier, Kristine A Justus, Paul Spearman, Russell E Ware, Jose A Cancelas, Michael B Jordan, Andrew B Herr, David A Hildeman, Jeffery D Molkentin
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254667 (2021)
The world is currently in a pandemic of COVID-19 (Coronavirus disease-2019) caused by a novel positive-sense, single-stranded RNA β-coronavirus referred to as SARS-CoV-2. Here we investigated rates of SARS-CoV-2 infection in the greater Cincinnati,
Externí odkaz:
https://doaj.org/article/567754193c2d4608b6803f79e3e2b6ff
Publikováno v:
Innate Immunity, Vol 25 (2019)
Neutrophils are the most abundant immune cell of the innate immune system and participate in essential immune functions. Heterogeneity within neutrophils has been documented, but it is difficult to distinguish if these are altered activation states o
Externí odkaz:
https://doaj.org/article/4a390860a5b242699e92f5d9ccf81b72
Autor:
Maha Almanan, Jana Raynor, Allyson Sholl, Mei Wang, Claire Chougnet, Rhonda D Cardin, David A Hildeman
Publikováno v:
PLoS Pathogens, Vol 13, Iss 8, p e1006507 (2017)
Cytomegalovirus (CMV) causes a persistent, lifelong infection. CMV persists in a latent state and undergoes intermittent subclinical viral reactivation that is quelled by ongoing T cell responses. While T cells are critical to maintain control of inf
Externí odkaz:
https://doaj.org/article/044cf3d209704fe59f1edf663fbfbbf8
Autor:
Christopher G McKnight, Suzanne C Morris, Charles Perkins, Zhenqi Zhu, David A Hildeman, Albert Bendelac, Fred D Finkelman
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188221 (2017)
CD1d-deficiency results in a selective deletion of NKT cells in mice that is reported to prevent murine allergic airway disease (AAD). Because we find 2-3 fold lower basal IL-4 production in CD1d- mice than in wild-type (WT) mice, we hypothesized tha
Externí odkaz:
https://doaj.org/article/178aa329dc0a43b086794a21f0a0537c
Autor:
Jennifer L Leddon, Chun-Yu Chen, Mark A Currier, Pin-Yi Wang, Francesca A Jung, Nicholas L Denton, Kevin M Cripe, Kellie B Haworth, Michael A Arnold, Amy C Gross, Timothy D Eubank, William F Goins, Joseph C Glorioso, Justus B Cohen, Paola Grandi, David A Hildeman, Timothy P Cripe
Publikováno v:
Molecular Therapy: Oncolytics, Vol 1, Iss C (2014)
Multiple studies have indicated that in addition to direct oncolysis, virotherapy promotes an antitumor cytotoxic T cell response important for efficacy. To study this phenomenon further, we tested three syngeneic murine sarcoma models that displayed
Externí odkaz:
https://doaj.org/article/bf8e7d0411ef44b882998c44c0e17aa8
Autor:
Jana eRaynor, Allyson eSholl, David R. Plas, Philippe eBouillet, Claire A Chougnet, David A Hildeman
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
We and others have shown that regulatory T cells (Treg) accumulate dramatically with age in both humans and mice. Such Treg accrual contributes to age-related immunosenescence as they reduce the response to tumors and parasite infection. While we rep
Externí odkaz:
https://doaj.org/article/85157bf847c4483b8d20e0075840e5db
Autor:
James D Phelan, Ingrid Saba, Hui Zeng, Christian Kosan, Malynda S Messer, H Andre Olsson, Jennifer Fraszczak, David A Hildeman, Bruce J Aronow, Tarik Möröy, H Leighton Grimes
Publikováno v:
PLoS Genetics, Vol 9, Iss 9, p e1003713 (2013)
Growth factor independent 1 (Gfi1) is a transcriptional repressor originally identified as a gene activated in T-cell leukemias induced by Moloney-murine-leukemia virus infection. Notch1 is a transmembrane receptor that is frequently mutated in human
Externí odkaz:
https://doaj.org/article/ecc354ee1fdc4214a1d727d92fc781bf
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13970 (2010)
RhoH is an hematopoietic-specific, GTPase-deficient Rho GTPase that plays a role in T development. We investigated the mechanisms of RhoH function in TCR signaling. We found that the association between Lck and CD3ζ was impaired in RhoH-deficient T
Externí odkaz:
https://doaj.org/article/b3a7cade93ee4d1b8322ff8db4555e69