Zobrazeno 1 - 10
of 1 326
pro vyhledávání: '"David A Hart"'
Autor:
Ania Kania-Richmond, Lauren A Beaupre, Geneviève Jessiman-Perreault, Danika Tribo, Jason Martyn, David A Hart, Jill Robert, Mel Slomp, C Allyson Jones
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0298618 (2024)
IntroductionThe Good Life with osteoArthritis: Denmark (GLA:DTM) is an evidence-based program designed for individuals with symptomatic hip and knee osteoarthritis (OA). This program has reported improvement in pain, quality of life and self-efficacy
Externí odkaz:
https://doaj.org/article/bbcc3ffabd524008b90c38149c400fd3
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199645 (2018)
INTRODUCTION:Statins are widely used to inhibit cholesterol production in the liver among people with hypercholesterolemia. A recent epidemiological study in the UK has shown that statin use (unlike elevated BMI) is not associated with an increased r
Externí odkaz:
https://doaj.org/article/8a739cfc2f2041be87440fc30808e20e
Autor:
Ryota Chijimatsu, Makoto Ikeya, Yukihiko Yasui, Yasutoshi Ikeda, Kosuke Ebina, Yu Moriguchi, Kazunori Shimomura, David A Hart, Yoshikawa Hideki, Nakamura Norimasa
Publikováno v:
Stem Cells International, Vol 2017 (2017)
Mesenchymal stem cells (MSCs) derived from induced pluripotent stem cells (iPSCs) are a promising cell source for the repair of skeletal disorders. Recently, neural crest cells (NCCs) were reported to be effective for inducing mesenchymal progenitors
Externí odkaz:
https://doaj.org/article/eb1360a30c8c44f180b3dfaabd9eba71
Autor:
Aisha S Ahmed, Jian Li, Alim M D Abdul, Mahmood Ahmed, Claes-Göran Östenson, Paul T Salo, Carolyn Hewitt, David A Hart, Paul W Ackermann
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170748 (2017)
Metabolic diseases such as diabetes mellitus type-II (DM-II) may increase the risk of suffering painful connective tissue disorders and tendon ruptures. The pathomechanisms, however, by which diabetes adversely affects connective tissue matrix metabo
Externí odkaz:
https://doaj.org/article/4b2751cf2469423a8c620fc27409a89a
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 6, Iss 4, Pp 100521- (2024)
Objective: To develop a novel scoring system to characterize osteoarthritis-related degeneration distinct from spontaneous subchondral bone lesions observed in the tibia and femur of male Sprague Dawley rats. Method: Knee joints from male rats follow
Externí odkaz:
https://doaj.org/article/17f74ff2d3ee44b9b55f37e4d30d13e6
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 124-131 (2024)
Treatments for articular cartilage injuries are still challenging, due in part to its avascular and aneural surroundings. Since the first report of autologous chondrocyte implantation, cell-based therapies have been extensively studied with a variety
Externí odkaz:
https://doaj.org/article/d4caba76b41c48ea94fdd00b1c9d56b7
Autor:
Roman J Krawetz, Yiru Elizabeth Wu, Liam Martin, Jerome B Rattner, John R Matyas, David A Hart
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43616 (2012)
Mesenchymal progenitor cells (MPCs) can differentiate into osteoblasts, adipocytes, and chondrocytes, and are in part responsible for maintaining tissue integrity. Recently, a progenitor cell population has been found within the synovial fluid that s
Externí odkaz:
https://doaj.org/article/fd1a3ce479274b04a845f5d17685cdc3
Autor:
Rafael Fortuna, David A. Hart, Keith A. Sharkey, Rachel A. Schachar, Kelly Johnston, Raylene A. Reimer
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-10 (2021)
Abstract Background Osteoarthritis (OA) is a chronic and painful condition where the articular cartilage surfaces progressively degenerate, resulting in loss of function and progressive disability. Obesity is a primary risk factor for the development
Externí odkaz:
https://doaj.org/article/b042d90871ea4919ba4540b61c664cf0
Autor:
David A. Hart
Publikováno v:
Frontiers in Sports and Active Living, Vol 3 (2021)
Physical activity, mobility or patterned mobility (i.e., exercise) is intrinsic to the functioning of Homo sapiens, and required for maintenance of health. Thus, systems such as the musculoskeletal and cardiovascular systems appear to require constan
Externí odkaz:
https://doaj.org/article/a2205aa2023c4215901e0ac02d978827
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Perspective: Musculoskeletal (MSK) tissues such as articular cartilage, menisci, tendons, and ligaments are often injured throughout life as a consequence of accidents. Joints can also become compromised due to the presence of inflammatory diseases s
Externí odkaz:
https://doaj.org/article/16397828618d4ef08cb09129a3d0ab70