Zobrazeno 1 - 10
of 181
pro vyhledávání: '"David A Garber"'
Autor:
David A Garber, James Mitchell, Debra Adams, Patricia Guenthner, Frank Deyounks, Shanon Ellis, Kristen Kelley, Ryan Johnson, Charles Dobard, Walid Heneine, Janet McNicholl
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194837 (2018)
Penile acquisition of HIV infection contributes substantially to the global epidemic. Our goal was to establish a preclinical macaque model of penile HIV infection for evaluating the efficacy of new HIV prevention modalities. Rhesus macaques were cha
Externí odkaz:
https://doaj.org/article/0085ca4002db4cf1a87aa03e66db3fb0
Autor:
Sundaram A Vishwanathan, Monica R Morris, Richard J Wolitski, Wei Luo, Charles E Rose, Dianna M Blau, Theodros Tsegaye, Sherif R Zaki, David A Garber, Leecresia T Jenkins, Tara C Henning, Dorothy L Patton, R Michael Hendry, Janet M McNicholl, Ellen N Kersh
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0120021 (2015)
BACKGROUND:Personal lubricant use is common during anal intercourse. Some water-based products with high osmolality and low pH can damage genital and rectal tissues, and the polymer polyquaternium 15 (PQ15) can enhance HIV replication in vitro. This
Externí odkaz:
https://doaj.org/article/b38b042c94094c33814d622e473b33f3
Autor:
Thomas H Vanderford, Chelsea Bleckwehl, Jessica C Engram, Richard M Dunham, Nichole R Klatt, Mark B Feinberg, David A Garber, Michael R Betts, Guido Silvestri
Publikováno v:
PLoS Pathogens, Vol 7, Iss 5, p e1002048 (2011)
SIV(mac239) infection of rhesus macaques (RMs) results in AIDS despite the generation of a strong antiviral cytotoxic T lymphocyte (CTL) response, possibly due to the emergence of viral escape mutants that prevent recognition of infected cells by CTL
Externí odkaz:
https://doaj.org/article/b16e21c157f742a6a0115aa053123a9a
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5445 (2009)
Modified Vaccinia virus Ankara (MVA) is a safe, highly attenuated orthopoxvirus that is being developed as a recombinant vaccine vector for immunization against a number of infectious diseases and cancers. However, the expression by MVA vectors of la
Externí odkaz:
https://doaj.org/article/cee2ea301d244e3186eeca917bf1477b
Autor:
David A. Garber, Debra R. Adams, Patricia Guenthner, James Mitchell, Kristen Kelley, Till Schoofs, Anna Gazumyan, Martha Nason, Michael S. Seaman, Janet McNicholl, Michel C. Nussenzweig, Walid Heneine
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Here, using a repeat-exposure penile SHIV infection model in macaques, the authors show that a single subcutaneous administration of a broadly neutralizing antibody (bNAb) exerts long-acting protection against both penile and vaginal virus exposure,
Externí odkaz:
https://doaj.org/article/415ea2495b55415ba7d408c549af42a5
Autor:
David A. Garber, Patricia Guenthner, Chunxia Zhao, James Mitchell, Shanon Ellis, Hongwei Jia, Marcos Manganare, Anna Gazumyan, Michael S. Seaman, Sundaram Ajay Vishwanathan, Walid Heneine, Janet M. McNicholl
Publikováno v:
AIDS. 37:723-731
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf51d775cc263b7c78e5b5829eb25168
https://doi.org/10.1097/qad.0000000000003472
https://doi.org/10.1097/qad.0000000000003472
Autor:
G.M. Anantharamaiah, David W. Garber, Dennis Goldberg, Eric Morrel, Geeta Datta, Mayakonda N. Palgunachari, Thomas C. Register, Susan E. Appt, C. Roger White
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 11, Pp 2075-2083 (2018)
Ac-hE18A-NH2 is a dual-domain apoE mimetic peptide that possesses the putative receptor binding domain from apoE (LRKLRKRLLR, denoted hE; residues 141–150) covalently attached to lipid-associating peptide 18A. Like apoE, Ac-hE18A-NH2 reduces plasma
Externí odkaz:
https://doaj.org/article/3f884e75404b453fa3fcb3632c8fa0ef
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 10, Pp 2007-2021 (2014)
Reduced levels of HDL cholesterol (HDL-C) are a strong independent predictor of coronary artery disease (CAD) risk. The major anti-atherogenic function of HDL is to mediate reverse cholesterol transport. This response is highly dependent on apoA-I an
Externí odkaz:
https://doaj.org/article/51e43cbecff94a7a80d75fc376f8c80f
Autor:
Kristen Kelley, Walid Heneine, Michel C. Nussenzweig, James Mitchell, Michael S. Seaman, Debra R. Adams, Till Schoofs, Janet M. McNicholl, Anna Gazumyan, David A. Garber, Patricia C. Guenthner, Martha Nason
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications
Nature Communications
Penile acquisition of HIV accounts for most infections among men globally. Nevertheless, candidate HIV interventions for men advance to clinical trials without preclinical efficacy data, due primarily to a paucity of relevant animal models of penile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c45ce43df201e8d03058d11a996d069
https://doaj.org/article/415ea2495b55415ba7d408c549af42a5
https://doaj.org/article/415ea2495b55415ba7d408c549af42a5
Autor:
Gaurav Nayyar, Vinod K. Mishra, Shaila P. Handattu, Mayakonda N. Palgunachari, Ronald Shin, David T. McPherson, Champion C.S. Deivanayagam, David W. Garber, Jere P. Segrest, G.M. Anantharamaiah
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 5, Pp 849-858 (2012)
To test the hypothesis that sidedness of interfacial arginine (Arg) in apoA-I mimetic peptides, similar to that observed in apoA-I (Bashtovyy, D. et al. 2011. Sequence conservation of apolipoprotein A-I affords novel insights into HDL structure-funct
Externí odkaz:
https://doaj.org/article/5936edca462f48c0a9aee53835e04f1e