Zobrazeno 1 - 10
of 245
pro vyhledávání: '"David A Andersson"'
Publikováno v:
eLife, Vol 6 (2017)
Transient receptor potential (TRP) ion channels in peripheral sensory neurons are functionally regulated by hydrolysis of the phosphoinositide PI(4,5)P2 and changes in the level of protein kinase mediated phosphorylation following activation of vario
Externí odkaz:
https://doaj.org/article/86a4970f11f14a319658eed27566dbb7
Autor:
Peter M Zygmunt, Anna Ermund, Pouya Movahed, David A Andersson, Charlotte Simonsen, Bo A G Jönsson, Anders Blomgren, Bryndis Birnir, Stuart Bevan, Alain Eschalier, Christophe Mallet, Ana Gomis, Edward D Högestätt
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81618 (2013)
Phospholipase C-mediated hydrolysis of phosphatidylinositol 4,5-bisphosphate generates diacylglycerol, inositol 1,4,5-trisphosphate and protons, all of which can regulate TRPV1 activity via different mechanisms. Here we explored the possibility that
Externí odkaz:
https://doaj.org/article/8dc9fcd4de7e4961b0b78813742bb4f0
Autor:
David A Andersson, Clive Gentry, Emily Light, Nisha Vastani, Julie Vallortigara, Angelika Bierhaus, Thomas Fleming, Stuart Bevan
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77986 (2013)
Diabetic neuropathy is a severe complication of long-standing diabetes and one of the major etiologies of neuropathic pain. Diabetes is associated with an increased formation of reactive oxygen species and the electrophilic dicarbonyl compound methyl
Externí odkaz:
https://doaj.org/article/3e1624368ac4447fa95f002ffdc217ec
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46917 (2012)
Hydrogen sulfide (H(2)S), which is produced endogenously from L-cysteine, is an irritant with pro-nociceptive actions. We have used measurements of intracellular calcium concentration, electrophysiology and behavioral measurements to show that the so
Externí odkaz:
https://doaj.org/article/ed56d0198c8b439880e755f929c5c25e
Autor:
David Emanuel Andersson, Thai Ha Le
Publikováno v:
Urban, Planning and Transport Research, Vol 11, Iss 1 (2023)
ABSTRACTA region’s science output depends on several spatial factors. A generalized least squares function with random effects was estimated to gauge the impact of such factors in European NUTS2 regions. The main findings are that output is positiv
Externí odkaz:
https://doaj.org/article/aea2d28735e3405696544ffd32c28bc9
Autor:
Sina Jami, Jennifer R. Deuis, Tabea Klasfauseweh, Xiaoyang Cheng, Sergey Kurdyukov, Felicity Chung, Andrei L. Okorokov, Shengnan Li, Jiangtao Zhang, Ben Cristofori-Armstrong, Mathilde R. Israel, Robert J. Ju, Samuel D. Robinson, Peng Zhao, Lotten Ragnarsson, Åsa Andersson, Poanna Tran, Vanessa Schendel, Kirsten L. McMahon, Hue N. T. Tran, Yanni K.-Y. Chin, Yifei Zhu, Junyu Liu, Theo Crawford, Saipriyaa Purushothamvasan, Abdella M. Habib, David A. Andersson, Lachlan D. Rash, John N. Wood, Jing Zhao, Samantha J. Stehbens, Mehdi Mobli, Andreas Leffler, Daohua Jiang, James J. Cox, Stephen G. Waxman, Sulayman D. Dib-Hajj, G. Gregory Neely, Thomas Durek, Irina Vetter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Voltage-gated sodium (NaV) channels are critical regulators of neuronal excitability and are targeted by many toxins that directly interact with the pore-forming α subunit, typically via extracellular loops of the voltage-sensing domains, o
Externí odkaz:
https://doaj.org/article/ef7fee6301d340c5b67edc494cc4b801
Publikováno v:
Prometheus, Vol 36, Iss 3, Pp 235-252 (2020)
A dynamic model that distinguishes between slow and fast processes shows that a triple helix model is impossible as a tool for promoting interdependencies among science, industry and government. We present a theorem to demonstrate that a triple he
Externí odkaz:
https://doaj.org/article/9f74151803004ca7b819d9f64f54371b
Publikováno v:
Applied Spatial Analysis and Policy. 16:923-938
Autor:
Zoe Paskins, Clare E Farmer, Fay Manning, David A Andersson, Tim Barlow, Felicity L Bishop, Christopher A Brown, Amanda Clark, Emma M Clark, Debra Dulake, Malvika Gulati, Christine L Le Maitre, Richard K Jones, John Loughlin, Deborah J Mason, Maura McCarron, Neil L Millar, Hemant Pandit, George Peat, Stephen M Richardson, Emma J Salt, E Jane Taylor, Linda Troeberg, Ruth K Wilcox, Elspeth Wise, Colin Wilkinson, Fiona E Watt
Publikováno v:
The Lancet Rheumatology
Richardson, S M 2022, ' Research priorities to reduce the impact of musculoskeletal disorders: a priority setting exercise with the child health and nutrition research initiative method ', The Lancet Rheumatology, vol. 4, no. 9, pp. e635-e645 . https://doi.org/10.1016/S2665-9913(22)00136-9
e645
e635
Richardson, S M 2022, ' Research priorities to reduce the impact of musculoskeletal disorders: a priority setting exercise with the child health and nutrition research initiative method ', The Lancet Rheumatology, vol. 4, no. 9, pp. e635-e645 . https://doi.org/10.1016/S2665-9913(22)00136-9
e645
e635
Involving research users in setting priorities for research is essential to ensure the outcomes are patient-centred and\ud maximise its value and impact. The Musculoskeletal Disorders Research Advisory Group Versus Arthritis led a\ud research priorit
Publikováno v:
Interdisciplinary information sciences. 28(1):63-74