Zobrazeno 1 - 10
of 378
pro vyhledávání: '"David A, Relman"'
Autor:
Hanna L. Berman, Daniela S. Aliaga Goltsman, Megan Anderson, David A. Relman, Benjamin J. Callahan
Publikováno v:
mSystems, Vol 9, Iss 6 (2024)
ABSTRACT The vaginal microbiome has been linked to negative health outcomes including preterm birth. Specific taxa, including Gardnerella spp., have been identified as risk factors for these conditions. Historically, microbiome analysis methods have
Externí odkaz:
https://doaj.org/article/6c4109408d534b258d066efcf5b00d41
Autor:
Elizabeth K. Costello, Daniel B. DiGiulio, Anna Robaczewska, Laura Symul, Ronald J. Wong, Gary M. Shaw, David K. Stevenson, Susan P. Holmes, Douglas S. Kwon, David A. Relman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The vaginal ecosystem is closely tied to human health and reproductive outcomes, yet its dynamics in the wake of childbirth remain poorly characterized. Here, we profile the vaginal microbiota and cytokine milieu of participants sampled long
Externí odkaz:
https://doaj.org/article/600f901d3bfc4b75bc41832ee63e7dc6
Autor:
Natasha K. Dudek, Jesus G. Galaz-Montoya, Handuo Shi, Megan Mayer, Cristina Danita, Arianna I. Celis, Tobias Viehboeck, Gong-Her Wu, Barry Behr, Silvia Bulgheresi, Kerwyn Casey Huang, Wah Chiu, David A. Relman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Much remains to be explored regarding the diversity of uncultured, host-associated microbes. Here, we describe rectangular bacterial structures (RBSs) in the mouths of bottlenose dolphins. DNA staining revealed multiple paired bands within R
Externí odkaz:
https://doaj.org/article/cae2d35f97474e77bc9c56e749b36bf6
Autor:
Elizabeth K. Costello, Daniel B. DiGiulio, Anna Robaczewska, Laura Symul, Ronald J. Wong, Gary M. Shaw, David K. Stevenson, Susan P. Holmes, Douglas S. Kwon, David A. Relman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/bc866d5a18f64f0f881c8512630d731b
Autor:
Philippa M. Wells, Daniel D. Sprockett, Ruth C. E. Bowyer, Yuko Kurushima, David A. Relman, Frances M. K. Williams, Claire J. Steves
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The oral microbiota is emerging as an influential factor of host physiology and disease state. Factors influencing oral microbiota composition have not been well characterised. In particular, there is a lack of population-based studies. We u
Externí odkaz:
https://doaj.org/article/189247387ab94ca08f49bb85b9ed73be
Autor:
Courtney J. Smith, Les Dethlefsen, Christopher Gardner, Linda Nguyen, Marcus Feldman, Elizabeth K. Costello, Oren Kolodny, David A. Relman
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT An outstanding question regarding the human gut microbiota is whether and how microbiota-directed interventions influence host phenotypic traits. Here, we employed a dietary intervention to probe this question in the context of lactose intol
Externí odkaz:
https://doaj.org/article/1511bb5f51084f1a88a38d426d2757f0
Autor:
Calvin C. Chan, Isaac T. W. Harley, Paul T. Pfluger, Aurelien Trompette, Traci E. Stankiewicz, Jessica L. Allen, Maria E. Moreno-Fernandez, Michelle S. M. A. Damen, Jarren R. Oates, Pablo C. Alarcon, Jessica R. Doll, Matthew J. Flick, Leah M. Flick, Joan Sanchez-Gurmaches, Rajib Mukherjee, Rebekah Karns, Michael Helmrath, Thomas H. Inge, Stuart P. Weisberg, Sünje J. Pamp, David A. Relman, Randy J. Seeley, Matthias H. Tschöp, Christopher L. Karp, Senad Divanovic
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Interactions between the immune system and adipose tissue contribute to the regulation of body weight, however, the underlying mechanisms remain incompletely understood. Here the authors dissect the role of two structurally and functionally similar i
Externí odkaz:
https://doaj.org/article/1874a0fdf3df440c914731f67be8205d
Autor:
Natasha K. Dudek, Alexandra D. Switzer, Elizabeth K. Costello, Michael J. Murray, Joseph A. Tomoleoni, Michelle M. Staedler, M. Tim Tinker, David A. Relman
Publikováno v:
Conservation Science and Practice, Vol 4, Iss 4, Pp n/a-n/a (2022)
Abstract The southern sea otter (Enhydra lutris nereis) is a threatened sub‐species in coastal ecosystems. To understand better the role of diet, monitor health, and enhance management of this and other marine mammal species, we characterized the o
Externí odkaz:
https://doaj.org/article/0408a278384e491680401fb4aaf8aeda
Autor:
Martin J. Blaser, Suzanne Devkota, Kathy D. McCoy, David A. Relman, Moran Yassour, Vincent B. Young
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-7 (2021)
Abstract For more than a century, the prenatal environment was considered sterile. Over the last few years, findings obtained with next-generation sequencing approaches from samples of the placenta, the amniotic fluid, meconium, and even fetal tissue
Externí odkaz:
https://doaj.org/article/f95f208b250a49009868f90af64d7c5f
Autor:
Gregory Lewis, Jacob L. Jordan, David A. Relman, Gregory D. Koblentz, Jade Leung, Allan Dafoe, Cassidy Nelson, Gerald L. Epstein, Rebecca Katz, Michael Montague, Ethan C. Alley, Claire Marie Filone, Stephen Luby, George M. Church, Piers Millett, Kevin M. Esvelt, Elizabeth E. Cameron, Thomas V. Inglesby
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-4 (2020)
A key security challenge with biosecurity threats is determining the responsible actor. In this Perspective, the authors review recent developments in using genetic sequence to assign a lab-of-origin and the potential protection it provides against m
Externí odkaz:
https://doaj.org/article/9823f4fbf1724d4b88eb96639987fdae