Zobrazeno 1 - 10
of 363
pro vyhledávání: '"David A, Christian"'
Autor:
Merz, Sarah, Senée, Valérie, Philippi, Anne, Oswald, Franz, Shaigan, Mina, Führer, Marita, Drewes, Cosima, Allgöwer, Chantal, Öllinger, Rupert, Heni, Martin, Boland, Anne, Deleuze, Jean-François, Birkhofer, Franziska, Gusmao, Eduardo G., Wagner, Martin, Hohwieler, Meike, Breunig, Markus, Rad, Roland, Siebert, Reiner, Messerer, David Alexander Christian, Costa, Ivan G., Alvarez, Fernando, Julier, Cécile, Kleger, Alexander, Heller, Sandra
Publikováno v:
In Cell Reports 26 November 2024 43(11)
Autor:
Eva-Maria Wolfschmitt, Josef Albert Vogt, Melanie Hogg, Ulrich Wachter, Nicole Stadler, Thomas Kapapa, Thomas Datzmann, David Alexander Christian Messerer, Andrea Hoffmann, Michael Gröger, Franziska Münz, René Mathieu, Simon Mayer, Tamara Merz, Pierre Asfar, Enrico Calzia, Peter Radermacher, Fabian Zink
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionSupplementation with increased inspired oxygen fractions has been suggested to alleviate the harmful effects of tissue hypoxia during hemorrhagic shock (HS) and traumatic brain injury. However, the utility of therapeutic hyperoxia in crit
Externí odkaz:
https://doaj.org/article/991bb70120ea4070bfbfec8007e78d77
Akademický článek
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Autor:
Marco Mannes, Rebecca Halbgebauer, Lisa Wohlgemuth, David Alexander Christian Messerer, Susa Savukoski, Anke Schultze, Bettina Berger, Christiane Leonie Knapp, Christoph Q. Schmidt, Daniel Fürst, Morten Hillmer, Reiner Siebert, Oskar Eriksson, Barbro Persson, Bo Nilsson, Kristina Nilsson Ekdahl, Markus Huber-Lang
Publikováno v:
Journal of Innate Immunity, Vol 15, Iss 1, Pp 412-427 (2023)
The complement system plays a crucial role in host defense, homeostasis, and tissue regeneration and bridges the innate and the adaptive immune systems. Although the genetic variants in complement C2 (c.839_849+17del; p.(Met280Asnfs*5)) and C8B (c.16
Externí odkaz:
https://doaj.org/article/62eadcbb7b1441f18d52e79ef47787c9
Autor:
Mannes, Marco, Pechtl, Veronika, Hafner, Susanne, Dopler, Arthur, Eriksson, Oskar, Manivel, Vivek Anand, Wohlgemuth, Lisa, Messerer, David Alexander Christian, Schrezenmeier, Hubert, Ekdahl, Kristina N., Nilsson, Bo, Jacobsen, Eva-Maria, Hoenig, Manfred, Huber-Lang, Markus, Braun, Christian K., Schmidt, Christoph Q.
Publikováno v:
In Blood Advances July 2023
Autor:
Hanna Schmidt, Larissa Melina Höpfer, Lisa Wohlgemuth, Christiane Leonie Knapp, Adam Omar Khalaf Mohamed, Laura Stukan, Frederik Münnich, Dominik Hüsken, Alexander Sebastian Koller, Alexander Elias Paul Stratmann, Paul Müller, Christian Karl Braun, Dorit Fabricius, Sebastian Felix Nepomuk Bode, Markus Huber-Lang, David Alexander Christian Messerer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cystic fibrosis (CF) is a monogenetic disease caused by an impairment of the cystic fibrosis transmembrane conductance regulator (CFTR). CF affects multiple organs and is associated with acute and chronic inflammation. In 2020, Elexacaftor–Tezacaft
Externí odkaz:
https://doaj.org/article/fb1a0fe813c7471a8811f9c132fcfa8b
Autor:
Thomas Datzmann, Franziska Münz, Andrea Hoffmann, Elena Moehrke, Martha Binzenhöfer, Michael Gröger, Thomas Kapapa, René Mathieu, Simon Mayer, Fabian Zink, Holger Gässler, Eva-Maria Wolfschmitt, Melanie Hogg, Tamara Merz, Enrico Calzia, Peter Radermacher, David Alexander Christian Messerer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Severe physical injuries and associated traumatic brain injury and/or hemorrhagic shock (HS) remain leading causes of death worldwide, aggravated by accompanying extensive inflammation. Retrospective clinical data indicated an association between mil
Externí odkaz:
https://doaj.org/article/debf330e5b544e33aff93261da4552b1
Autor:
Joseph A. Pereira, Zachary Lanzar, Joseph T. Clark, Andrew P. Hart, Bonnie B. Douglas, Lindsey Shallberg, Keenan O’Dea, David A. Christian, Christopher A. Hunter
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
At homeostasis, a substantial proportion of Foxp3+ T regulatory cells (Tregs) have an activated phenotype associated with enhanced TCR signals and these effector Treg cells (eTregs) co-express elevated levels of PD-1 and CTLA-4. Short term in vivo bl
Externí odkaz:
https://doaj.org/article/ca90c2086bee408fa59ebce36148ce51
Autor:
Eva-Maria Wolfschmitt, Melanie Hogg, Josef Albert Vogt, Fabian Zink, Ulrich Wachter, Felix Hezel, Xiaomin Zhang, Andrea Hoffmann, Michael Gröger, Clair Hartmann, Holger Gässler, Thomas Datzmann, Tamara Merz, Andreas Hellmann, Christine Kranz, Enrico Calzia, Peter Radermacher, David Alexander Christian Messerer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSodium thiosulfate (Na2S2O3), an H2S releasing agent, was shown to be organ-protective in experimental hemorrhage. Systemic inflammation activates immune cells, which in turn show cell type-specific metabolic plasticity with modifications
Externí odkaz:
https://doaj.org/article/6aec3c551b6a4003a7c9b5ece2534655
Autor:
Doreen Tabea Spiegelburg, Marco Mannes, Anke Schultze, Frieder Scheibenberger, Frederik Müller, Amadeo Klitzing, David Alexander Christian Messerer, Kristina Nilsson Ekdahl, Bo Nilsson, Markus Huber-Lang, Christian Karl Braun
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280069 (2023)
BackgroundSurface compatibility with blood is critical both for scientific investigations on hemostasis and clinical applications. Regarding in vitro and ex vivo investigations, minimal alteration in physiological hemostasis is of particular importan
Externí odkaz:
https://doaj.org/article/580d7c3af87646e39c9354214aea2fe6