Zobrazeno 1 - 10
of 1 177
pro vyhledávání: '"David A, Brenner"'
Autor:
Ekaterina Royba, Igor Shuryak, Brian Ponnaiya, Mikhail Repin, Sergey Pampou, Charles Karan, Helen Turner, Guy Garty, David J. Brenner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract In major radiological events, rapid assays to detect ionizing radiation exposure are crucial for effective medical interventions. The purpose of these assays is twofold: to categorize affected individuals into groups for initial treatments,
Externí odkaz:
https://doaj.org/article/600f4914a27c4250a926c76bb11ff824
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract This study explores the impact of densely-ionizing radiation on non-cancer and cancer diseases, focusing on dose, fractionation, age, and sex effects. Using historical mortality data from approximately 21,000 mice exposed to fission neutrons
Externí odkaz:
https://doaj.org/article/b7a0d39ce58042628a932c83236a22d7
Autor:
Evan L. Pannkuk, Evagelia C. Laiakis, Guy Garty, Sunil Bansal, Meth M. Jayatilake, Yuewen Tan, Brian Ponnaiya, Xuefeng Wu, Sally A. Amundson, David J. Brenner, Albert J. Fornace
Publikováno v:
ACS Omega, Vol 9, Iss 32, Pp 35182-35196 (2024)
Externí odkaz:
https://doaj.org/article/c9ef3729879e4462a62c22eee403565f
Autor:
Daniel Naveed Tavakol, Trevor R. Nash, Youngbin Kim, Pamela L. Graney, Martin Liberman, Sharon Fleischer, Roberta I. Lock, Aaron O'Donnell, Leah Andrews, Derek Ning, Keith Yeager, Andrew Harken, Naresh Deoli, Sally A. Amundson, Guy Garty, Kam W. Leong, David J. Brenner, Gordana Vunjak‐Novakovic
Publikováno v:
Advanced Science, Vol 11, Iss 42, Pp n/a-n/a (2024)
Abstract Galactic cosmic radiation (GCR) is one of the most serious risks posed to astronauts during missions to the Moon and Mars. Experimental models capable of recapitulating human physiology are critical to understanding the effects of radiation
Externí odkaz:
https://doaj.org/article/7e92c8cf27d14e3786d3ad5685ed5b4e
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionTreating head and neck squamous cell carcinomas (HNSCC), especially human papillomavirus negative (HPV-) and locally advanced cases, remains difficult. Our previous analyses of radiotherapy-only HNSCC clinical trials data using mechanisti
Externí odkaz:
https://doaj.org/article/b5e94b5f84ce41f7838cfd1636ca9990
Autor:
Manuela Buonanno, Norman J. Kleiman, David Welch, Raabia Hashmi, Igor Shuryak, David J. Brenner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract An emerging intervention for control of airborne-mediated pandemics and epidemics is whole-room far-UVC (200–235 nm). Laboratory studies have shown that 222-nm light inactivates airborne pathogens, potentially without harm to exposed occup
Externí odkaz:
https://doaj.org/article/bce75f2641cb4c2785ebb3a68d12e95d
Autor:
Hyun Young Kim, Sadatsugu Sakane, Alvaro Eguileor, Raquel Carvalho Gontijo Weber, Wonseok Lee, Xiao Liu, Kevin Lam, Kei Ishizuka, Sara Brin Rosenthal, Karin Diggle, David A. Brenner, Tatiana Kisseleva
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 1, Pp 93-106 (2024)
Liver fibrosis of different etiologies is a serious health problem worldwide. There is no effective therapy available for liver fibrosis except the removal of the underlying cause of injury or liver transplantation. Development of liver fibrosis is c
Externí odkaz:
https://doaj.org/article/0f9a90d94d5e4bd0a2e4ea88044b0319
Autor:
Hyun Young Kim, Wonseok Lee, Xiao Liu, Haeum Jang, Sadatsugu Sakane, Raquel Carvalho-Gontijo Weber, Karin Diggle, Samuel A. Kerk, Christian M. Metallo, Tatiana Kisseleva, David A. Brenner
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103111- (2024)
Summary: Currently, there is no effective treatment for obesity and alcohol-associated liver diseases, partially due to the lack of translational human models. Here, we present a protocol to generate 3D human liver spheroids that contain all the live
Externí odkaz:
https://doaj.org/article/4d3e50db289e472d86f78e55cfae2e45
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract The biological effects of densely-ionizing radiations such as neutrons and heavy ions encountered in space travel, nuclear incidents, and cancer radiotherapy, significantly differ from those of sparsely-ionizing photons and necessitate a com
Externí odkaz:
https://doaj.org/article/2cafb4268b3b428eb2f0fca131e355c8
Autor:
Igor Shuryak, Shanaz A. Ghandhi, Evagelia C. Laiakis, Guy Garty, Xuefeng Wu, Brian Ponnaiya, Emma Kosowski, Evan Pannkuk, Salan P. Kaur, Andrew D. Harken, Naresh Deoli, Albert J. Fornace, David J. Brenner, Sally A. Amundson
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract There is a persistent risk of a large-scale malicious or accidental exposure to ionizing radiation that may affect a large number of people. Exposure will consist of both a photon and neutron component, which will vary in magnitude between i
Externí odkaz:
https://doaj.org/article/2d5470e0716145d4af6f52e648b8df37