Zobrazeno 1 - 10
of 22
pro vyhledávání: '"David Ramonet"'
Autor:
Sol Beccari, Virginia Sierra-Torre, Jorge Valero, Marta Pereira-Iglesias, Mikel García-Zaballa, Federico N. Soria, Laura De Las Heras-Garcia, Alejandro Carretero-Guillen, Estibaliz Capetillo-Zarate, Maria Domercq, Paloma R. Huguet, David Ramonet, Ahmed Osman, Wei Han, Cecilia Dominguez, Travis E. Faust, Omar Touzani, Olatz Pampliega, Patricia Boya, Dorothy Schafer, Guillermo Mariño, Emmanuelle Canet-Soulas, Klas Blomgren, Ainhoa Plaza-Zabala, Amanda Sierra
Publikováno v:
Scopus
31 p.-12 fig.-1 tab. We dedicate this paper to Takashi Umekawa, who generated the HI model at the Karolinska Institute, and unfortunately passed away in 2018.
Microglial phagocytosis of apoptotic debris prevents buildup damage of neighbor neuron
Microglial phagocytosis of apoptotic debris prevents buildup damage of neighbor neuron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014b66a4df545c9971c93aa98a94ab37
Autor:
Jorge Valero, Ahmed M. Osman, Alejandro Carretero-Guillén, Guillermo Mariño, Amanda Sierra, Wei Han, Mikel Garcia-Zaballa, David Ramonet, Dorothy P. Schafer, Omar Touzani, Travis E Faust, Patricia Boya, Estibaliz Capetillo-Zarate, Virginia Sierra-Torre, Emmanuelle Canet-Soulas, Ainhoa Plaza-Zabala, Paloma Huguet, María Domercq, Sol Beccari, Klas Blomgren, Cecilia A. Dominguez
Microglial phagocytosis is rapidly emerging as a therapeutic target in neurodegenerative and neurological disorders. An efficient removal of cellular debris is necessary to prevent buildup damage of neighbor neurons and the development of an inflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::007996eefa8fa4774f8410200781ea41
https://doi.org/10.1101/2021.11.12.468358
https://doi.org/10.1101/2021.11.12.468358
Publikováno v:
Neurobiology of Disease, Vol 26, Iss 3, Pp 661-670 (2007)
HIV-1 infection causes, with increasing prevalence, neurological disorders characterized in part by neuronal cell death. The HIV-1 protein Tat has been shown to be directly and indirectly neurotoxic. Here, we tested the hypothesis that a non-neurotox
Externí odkaz:
https://doaj.org/article/7f884989104e465d905b7fa5fb6c4d6a
Autor:
David Ramonet, João Paulo L Daher, Brian M Lin, Klodjan Stafa, Jaekwang Kim, Rebecca Banerjee, Marie Westerlund, Olga Pletnikova, Liliane Glauser, Lichuan Yang, Ying Liu, Deborah A Swing, M Flint Beal, Juan C Troncoso, J Michael McCaffery, Nancy A Jenkins, Neal G Copeland, Dagmar Galter, Bobby Thomas, Michael K Lee, Ted M Dawson, Valina L Dawson, Darren J Moore
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18568 (2011)
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene cause late-onset, autosomal dominant familial Parkinson's disease (PD) and also contribute to idiopathic PD. LRRK2 mutations represent the most common cause of PD with clinical and neurochemi
Externí odkaz:
https://doaj.org/article/01d6a4bc1a0c4047be5141533aeb099b
Autor:
Luigi Laghi, Jens U. Marquardt, Lude Franke, Harm-Jan Westra, Ralf Kiesslich, Cisca Wijmenga, Julio Perez de la Serna, Rosario Cuomo, Jan Tack, Peter R. Galle, Ines Gockel, Henning G. Schulz, Giovanni Sarnelli, Daniel Drescher, Jessica Becker, Stefan Niebisch, Elisabeth Mangold, Anna Latiano, Paul I.W. de Bakker, V. Annese, Uberto Fumagalli, Antonio Ruiz de León, Michael T. Heneka, Alexander J. Eckardt, Per Hoffmann, Mira M. Wouters, Hans Dieter Allescher, Julian Zimmermann, Timo Hess, Werner Kneist, Elena Urcelay, Ana G. Vigo, Hauke Lang, Markus M. Nöthen, Gosia Trynka, Henning R. Gockel, Burkhard H.A. von Rahden, Vinod Kumar, Karl-Peter Hopfner, David Ramonet, Stefan Herms, Stefanie Heilmann, Michael Knapp, Michaela Müller, Guy E. Boeckxstaens, Johannes Schumacher, Manuel Mattheisen
Publikováno v:
BASE-Bielefeld Academic Search Engine
Nature Genetics, 46(8), 901-904. Nature Publishing Group
Gockel, I, Becker, J, Wouters, M M, Niebisch, S, Gockel, H R, Hess, T, Ramonet, D, Zimmermann, J, Vigo, A G, Trynka, G, de León, A R, de la Serna, J P, Urcelay, E, Kumar, V, Franke, L, Westra, H-J, Drescher, D, Kneist, W, Marquardt, J U, Galle, P R, Mattheisen, M, Annese, V, Latiano, A, Fumagalli, U, Laghi, L, Cuomo, R, Sarnelli, G, Müller, M, Eckardt, A J, Tack, J, Hoffmann, P, Herms, S, Mangold, E, Heilmann, S, Kiesslich, R, von Rahden, B H A, Allescher, H-D, Schulz, H G, Wijmenga, C, Heneka, M T, Lang, H, Hopfner, K-P, Nöthen, M M, Boeckxstaens, G E, de Bakker, P I W, Knapp, M & Schumacher, J 2014, ' Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia ', Nature Genetics . https://doi.org/10.1038/ng.3029
Nature Genetics, 46(8), 901-904. Nature Publishing Group
Gockel, I, Becker, J, Wouters, M M, Niebisch, S, Gockel, H R, Hess, T, Ramonet, D, Zimmermann, J, Vigo, A G, Trynka, G, de León, A R, de la Serna, J P, Urcelay, E, Kumar, V, Franke, L, Westra, H-J, Drescher, D, Kneist, W, Marquardt, J U, Galle, P R, Mattheisen, M, Annese, V, Latiano, A, Fumagalli, U, Laghi, L, Cuomo, R, Sarnelli, G, Müller, M, Eckardt, A J, Tack, J, Hoffmann, P, Herms, S, Mangold, E, Heilmann, S, Kiesslich, R, von Rahden, B H A, Allescher, H-D, Schulz, H G, Wijmenga, C, Heneka, M T, Lang, H, Hopfner, K-P, Nöthen, M M, Boeckxstaens, G E, de Bakker, P I W, Knapp, M & Schumacher, J 2014, ' Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia ', Nature Genetics . https://doi.org/10.1038/ng.3029
Idiopathic achalasia is characterized by a failure of the lower esophageal sphincter to relax due to a loss of neurons in the myenteric plexus(1,2). This ultimately leads to massive dilatation and an irreversibly impaired megaesophagus. We performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b02350b253ac6a701faf5c4abdda99
https://doi.org/10.1038/ng.3029
https://doi.org/10.1038/ng.3029
Autor:
Wiesje M. van der Flier, Eckart Rüther, Henne Holstege, Johannes Kornhuber, Jens Wiltfang, Charlotte E. Teunissen, Alison Goate, Piotr Lewczuk, Carlos Cruchaga, David Ramonet, Frank Jessen, Markus M. Nöthen, Oliver Peters, Michael T. Heneka, Adam C. Naj, Markus P. Kummer, Christine Herold, Heike Kölsch, R. Heun, Wolfgang Maier, Philip Scheltens, Lutz Frölich, Amy Gerrish, Julius Popp, Vincent Chouraki, Céline Bellenguez, Alzheimer's Disease Neuroimaging Initiative, Dmitriy Drichel, Tim Becker, Lara Buscemi, André Lacour, Monique M.B. Breteler, Stefan Herms, Michael Hüll, Stefanie Heilmann, Alfredo Ramirez, Per Hoffmann, Eva Louwersheimer
Publikováno v:
Human Molecular Genetics, Vol. 23, No 24 (2014) pp. 6644-6658
Ramirez, A, van der Flier, W M, Herold, C, Ramonet, D, Heilmann, S, Lewczuk, P, Popp, J, Lacour, A, Drichel, D, Louwersheimer, E, Kummer, M P, Cruchaga, C, Hoffmann, P, Teunissen, C E, Holstege, H, Kornhuber, J, Peters, O, Naj, A C, Chouraki, V, Bellenguez, C, Gerrish, A, Heun, R, Frolich, L, Hull, M, Buscemi, L, Herms, S, Kolsch, H, Scheltens, P, Breteler, M M, Ruther, E, Wiltfang, J, Goate, A, Jessen, F, Maier, W, Heneka, M T, Becker, T & Nothen, M M 2014, ' SUCLG2 identified as both a determinator of CSF Abeta1-42 levels and an attenuator of cognitive decline in Alzheimer's disease ', Human Molecular Genetics, vol. 23, no. 24, pp. 6644-6658 . https://doi.org/10.1093/hmg/ddu372
Human molecular genetics 23(24), 6644-6658 (2014). doi:10.1093/hmg/ddu372
Human Molecular Genetics, 23(24), 6644-6658. Oxford University Press
Ramirez, A, van der Flier, W M, Herold, C, Ramonet, D, Heilmann, S, Lewczuk, P, Popp, J, Lacour, A, Drichel, D, Louwersheimer, E, Kummer, M P, Cruchaga, C, Hoffmann, P, Teunissen, C E, Holstege, H, Kornhuber, J, Peters, O, Naj, A C, Chouraki, V, Bellenguez, C, Gerrish, A, Heun, R, Frolich, L, Hull, M, Buscemi, L, Herms, S, Kolsch, H, Scheltens, P, Breteler, M M, Ruther, E, Wiltfang, J, Goate, A, Jessen, F, Maier, W, Heneka, M T, Becker, T & Nothen, M M 2014, ' SUCLG2 identified as both a determinator of CSF Abeta1-42 levels and an attenuator of cognitive decline in Alzheimer's disease ', Human Molecular Genetics, vol. 23, no. 24, pp. 6644-6658 . https://doi.org/10.1093/hmg/ddu372
Human molecular genetics 23(24), 6644-6658 (2014). doi:10.1093/hmg/ddu372
Human Molecular Genetics, 23(24), 6644-6658. Oxford University Press
Cerebrospinal fluid amyloid-beta 1-42 (Aβ1-42) and phosphorylated Tau at position 181 (pTau181) are biomarkers of Alzheimer's disease (AD). We performed an analysis and meta-analysis of genome-wide association study data on Aβ1-42 and pTau181 in AD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e0346a024e4af22aa36d41fa2a4beaf
http://doc.rero.ch/record/296237/files/ddu372.pdf
http://doc.rero.ch/record/296237/files/ddu372.pdf
Autor:
Jean-Jacques Meister, Boris Hinz, Franco Klingberg, David Ramonet, Aurélie Formey, Lara Buscemi, Josiane Smith-Clerc
Publikováno v:
Current Biology. 21:2046-2054
Summary Background TGF-β1 controls many pathophysiological processes including tissue homeostasis, fibrosis, and cancer progression. Together with its latency-associated peptide (LAP), TGF-β1 binds to the latent TGF-β1-binding protein-1 (LTBP-1),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4261a8654aafaa8cab40bf3ac31e54
https://doi.org/10.1016/j.cub.2011.11.037
https://doi.org/10.1016/j.cub.2011.11.037
Autor:
Michael Leitges, Hee-Sup Shin, Jonathan D. Geiger, Saobo Lei, Zhaoyang Xiao, David Ramonet, Pan-Yue Deng, Toshimitsu Matsui, Archana Jha, James E. Porter
Publikováno v:
The Journal of Neuroscience. 30:5136-5148
Cholecystokinin (CCK), a neuropeptide originally discovered in the gastrointestinal tract, is abundantly distributed in the mammalian brains including the hippocampus. Whereas CCK has been shown to increase glutamate concentration in the perfusate of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3eb9b1acfc2003125e21f1384d08996
https://doi.org/10.1523/jneurosci.5711-09.2010
https://doi.org/10.1523/jneurosci.5711-09.2010
Publikováno v:
Journal of Neurochemistry. 107:317-328
Mitochondrial dysfunction has long been associated with Parkinson's disease (PD). In particular, complex I impairment and subsequent oxidative stress have been widely demonstrated in experimental models of PD and in post-mortem PD samples. A recent w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de6f813c3bfac6c48f98a070490c7ae9
https://doi.org/10.1111/j.1471-4159.2008.05604.x
https://doi.org/10.1111/j.1471-4159.2008.05604.x
Publikováno v:
Neurobiology of Disease, Vol 26, Iss 3, Pp 661-670 (2007)
HIV-1 infection causes, with increasing prevalence, neurological disorders characterized in part by neuronal cell death. The HIV-1 protein Tat has been shown to be directly and indirectly neurotoxic. Here, we tested the hypothesis that a non-neurotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec1ef9e151dfbaf5488be1bbf56cd9c9
https://doi.org/10.1016/j.nbd.2007.03.004
https://doi.org/10.1016/j.nbd.2007.03.004