Zobrazeno 1 - 10
of 25
pro vyhledávání: '"David Mankoff"'
Autor:
Prashanth K. Padakanti, Shihong Li, Alexander Schmitz, David Mankoff, Robert H. Mach, Hsiaoju S. Lee
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 4, Iss 1, Pp 1-9 (2019)
Abstract Background L-Glutamine (L-Gln) is the most abundant amino acid present in the human body and is involved in numerous metabolic pathways. Glutaminolysis is the metabolic process deployed by many aggressive cancers such as triple negative brea
Externí odkaz:
https://doaj.org/article/9f2d917e34804a0cbc4c9051be2f52e8
Autor:
David Mankoff, Steven J. Isakoff, Stefan A. Carp, David A. Boas, Nola Hylton, Bradley S. Snyder, Mitchell Schnall, So Hyun Chung, Arjun G. Yodh, Peter A. Kaufman, Shudong Jiang, Brian W. Pogue, Keith D. Paulsen, Wei Yang, Darren Roblyer, Rita S. Mehta, Philip M. Carpenter, Albert E. Cerussi, Thomas D. O'Sullivan, Anaïs Leproux, Zheng Zhang, Bruce J. Tromberg
Accrual table by institution.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507533b8bc313f4a1fa46e37feb8e1ab
https://doi.org/10.1158/0008-5472.22413452
https://doi.org/10.1158/0008-5472.22413452
Autor:
David Mankoff, Steven J. Isakoff, Stefan A. Carp, David A. Boas, Nola Hylton, Bradley S. Snyder, Mitchell Schnall, So Hyun Chung, Arjun G. Yodh, Peter A. Kaufman, Shudong Jiang, Brian W. Pogue, Keith D. Paulsen, Wei Yang, Darren Roblyer, Rita S. Mehta, Philip M. Carpenter, Albert E. Cerussi, Thomas D. O'Sullivan, Anaïs Leproux, Zheng Zhang, Bruce J. Tromberg
The prospective multicenter ACRIN 6691 trial was designed to evaluate whether changes from baseline to mid-therapy in a diffuse optical spectroscopic imaging (DOSI)–derived imaging endpoint, the tissue optical index (TOI), predict pathologic comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eeac94670e6f20fdf647fb7fd2aec71
https://doi.org/10.1158/0008-5472.c.6508715.v1
https://doi.org/10.1158/0008-5472.c.6508715.v1
Autor:
David Mankoff, Steven J. Isakoff, Stefan A. Carp, David A. Boas, Nola Hylton, Bradley S. Snyder, Mitchell Schnall, So Hyun Chung, Arjun G. Yodh, Peter A. Kaufman, Shudong Jiang, Brian W. Pogue, Keith D. Paulsen, Wei Yang, Darren Roblyer, Rita S. Mehta, Philip M. Carpenter, Albert E. Cerussi, Thomas D. O'Sullivan, Anaïs Leproux, Zheng Zhang, Bruce J. Tromberg
List of Chemotherapy regimens used in this study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e0ce02bc78085df33a7e85b40fb766
https://doi.org/10.1158/0008-5472.22413455
https://doi.org/10.1158/0008-5472.22413455
Publikováno v:
Cancer Research. 82:P5-08
OBJECTIVES: Upregulated glutamine metabolism is an important metabolic signature for aggressive and treatment-resistant cancers, including many triple negative breast cancers (TNBCs). Glutamate (Glu) produced from glutamine (Gln) via mitochondrial gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58754463f7b6da07d199e65bb4bb9869
https://doi.org/10.1158/1538-7445.sabcs21-p5-08-18
https://doi.org/10.1158/1538-7445.sabcs21-p5-08-18
Publikováno v:
J Nucl Med
Aggressive cancers such as triple-negative breast cancer (TNBC) avidly metabolize glutamine as a feature of their malignant phenotype. The conversion of glutamine to glutamate by the glutaminase enzyme represents the first and rate-limiting step of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e2dc79b4a801e733d6dca219f6bc2e
https://europepmc.org/articles/PMC9841257/
https://europepmc.org/articles/PMC9841257/
Autor:
Eva-Maria Ratai, Zheng Zhang, James Fink, Mark Muzi, Lucy Hanna, Erin Greco, Todd Richards, Daniel Kim, Ovidiu C Andronesi, Akiva Mintz, Lale Kostakoglu, Melissa Prah, Benjamin Ellingson, Kathleen Schmainda, Gregory Sorensen, Daniel Barboriak, David Mankoff, Elizabeth R Gerstner, ACRIN 6684 trial group
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198548 (2018)
A multi-center imaging trial by the American College of Radiology Imaging Network (ACRIN) "A Multicenter, phase II assessment of tumor hypoxia in glioblastoma using 18F Fluoromisonidazole (FMISO) with PET and MRI (ACRIN 6684)", was conducted to asses
Externí odkaz:
https://doaj.org/article/82531403d7ea48b78564101715f30dcd
Autor:
Laura Q Chow, Rafael Santana-Davila, Austin Pantel, Mara Roth, Leslie N Anderson, Alan Failor, Robert Doot, David Mankoff
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178325 (2017)
This trial was conducted to evaluate the ability of pazopanib to overcome therapeutic 131I resistance.This phase 1 trial assesses the combination of pazopanib and escalating doses of radioiodine (131I) in patients with recurrent or metastatic thyroid
Externí odkaz:
https://doaj.org/article/9d183830252d4584a74cebbcc21232d5
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 63(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9aa48f582d134c36db817760d5fa436d
https://pubmed.ncbi.nlm.nih.gov/35487571
https://pubmed.ncbi.nlm.nih.gov/35487571
Autor:
Yushe Dang, Jennifer Childs, Doreen Higgins, Sasha E. Stanton, Janet F. Eary, Edmond A. Marzbani, David Mankoff, Lupe G. Salazar, Jessica Reichow, Mary L. Disis
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 4, Iss 1 (2016)
Background The ability of T-cells to traffic to and penetrate tumors impacts the clinical efficacy of T-cell therapy therefore methods to track transferred T-cells in vivo are needed. In this preliminary report, we evaluated the use of concurrent SPE
Externí odkaz:
https://doaj.org/article/b5e28295407f4edd850752e3acefe5fa