Zobrazeno 1 - 10
of 18
pro vyhledávání: '"David Limal"'
Autor:
Serge Sagodira, Pascal Breton, N. Bru, Nathalie Colin, David Limal, David Bonnafous, Virginie Larras, D. Roy, Elias Fattal, Patrick Couvreur
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 68:479-495
In the past 20 years, mainly with the sponsorship of Laboratoires UPSA (France) and, afterwards, its spin-off company Virsol (France), several authors have studied methylidene malonate-based polymers used in drug delivery approaches and in the develo
Autor:
Julien Furrer, Alberto Bianco, David Limal, Maryse Bourdonneau, Karim Elbayed, Jésus Raya, Martial Piotto
Publikováno v:
Magnetic Resonance in Chemistry. 40:123-132
Under magic angle spinning, the NMR spectrum of the tetrapeptide Ala-Ile-Gly-Met bound to a Wang resin, and swollen in DMF, exhibits proton and carbon linewidths that are sharp enough to allow the complete characterization of the peptide using classi
Publikováno v:
European Polymer Journal. 37:1519-1526
The oligomerization of styrene in the presence of α-thioglycerol, a functionalized thiol, was studied in order to control the synthesis of ω-dihydroxylated polystyrene oligomers. Two different reaction processes were investigated: a batch process,
Autor:
Alberto Bianco, Jean-Paul Briand, Julien Furrer, David Limal, Karim Elbayed, Maryse Bourdonneau, Jésus Raya, Gilles Guichard, Martial Piotto
Publikováno v:
Journal of the American Chemical Society. 123:4130-4138
The structure of the 19-amino acid peptide epitope, corresponding to the 141-159 sequence of capsid viral protein VP1 of foot-and-mouth disease virus (FMDV), bound to three different resins, namely, polystyrene-MBHA, PEGA, and POEPOP, has been determ
Publikováno v:
Scopus-Elsevier
The synthesis of ω-dihydroxylated polystyrene oligomers was performed by free radical polymerization of styrene in the presence of α-thioglycerol. Monitoring styrene and α-thioglycerol concentration evolution by gas chromatography during a batch p
Publikováno v:
Tetrahedron Letters
Tetrahedron Letters, Elsevier, 1999, 40 (14), pp.2749-2752. ⟨10.1016/S0040-4039(99)00288-9⟩
Tetrahedron Letters, Elsevier, 1999, 40 (14), pp.2749-2752. ⟨10.1016/S0040-4039(99)00288-9⟩
The synthesis of Boc- or Fmoc-monoprotected propylenediamine derivatives is reported starting from N-protected α-amino acids. The introduction of these building blocks on solid support via the formation of a urea moiety leads to a new pseudopeptide
Autor:
André Aubry, Michel Marraud, David Limal, Régis Vanderesse, André Vicherat, C. Didierjean, V. Grand
Publikováno v:
Journal of the American Chemical Society. 120:9444-9451
The homologous RCO-Pro-Xaa-NHR‘ model pseudodipeptides containing the reduced peptide (CαCH2NHCα), reduced azapeptide (CαCH2NHNα), methyleneoxy (CαCH2OCα), and iminoazapeptide (CαCHNNα) surrogate of the middle amide group have been prepared
Publikováno v:
Tetrahedron Letters. 39:4239-4242
A rapid and efficient one-step synthesis of N-protected β-amino dimethylhydroxamates starting from diazo ketones is reported. A Fmoc-protected β-amino aldehyde obtained by reduction of its corresponding dimethylhydroxamate was incorporated during s
Publikováno v:
Tetrahedron Letters. 35:3711-3714
The semicarbazone moiety (CCHNNRCONHC), either obtained by coupling a peptide aldehyde with a semicarbazide, or by action of an alkylisocyanate on a peptide hydrazone, is a dipeptide isostere. The structure of four imino aza dipepti
Autor:
Alain Razafindratsita, Henri Chabre, Hélène Moussu, Laurent Mascarell, Philippe Moingeon, David Limal, Carlo Chiavaroli, Laurence Van Overtvelt, S. Horiot, Stéphane Moutel, Vincent Lombardi, Jacques Bauer
Publikováno v:
Vaccine. 26(1)
Summary In this study, we tested two triacylated pseudo-dipeptidic molecules, OM-197-MP-AC and OM-294-BA-MP as candidate adjuvants for allergy vaccines. Both molecules induce human dendritic cell (h-DC) maturation and polarize naive T cells toward th