Zobrazeno 1 - 10
of 136
pro vyhledávání: '"David Dunlap"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract After an RNA polymerase reaches a terminator, instead of dissociating from the template, it may diffuse along the DNA and recommence RNA synthesis from the previous or a different promoter. Magnetic tweezers were used to monitor such seconda
Externí odkaz:
https://doaj.org/article/251d26960a1a4c2092b959a30cc3e8e3
Autor:
Jin Qian, Allison Cartee, Wenxuan Xu, Yan Yan, Bing Wang, Irina Artsimovitch, David Dunlap, Laura Finzi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract RNA polymerases must transit through protein roadblocks to produce full-length transcripts. Here we report real-time measurements of Escherichia coli RNA polymerase passing through different barriers. As intuitively expected, assisting force
Externí odkaz:
https://doaj.org/article/2fd007c86b294e6ba3514a48941511de
12 W~UMa-type systems were observed at 3.6 cm with a goal to compare their radio luminosities with those of non-contact, rapidly rotating, late-type stars. Only 3 systems, all of spectral type K, have been detected. The detections and (low) upper lim
Externí odkaz:
http://arxiv.org/abs/astro-ph/9502082
Autor:
Yue Lu, Zsuzsanna Voros, Gustavo Borjas, Cristin Hendrickson, Keith Shearwin, David Dunlap, Laura Finzi
Publikováno v:
FEBS Letters. 596:1994-2006
DNA can act as a scaffold for the cooperative binding of protein oligomers. For example, the phage 186 CI repressor forms a wheel of seven dimers wrapped in DNA with specific binding sites, while phage λ CI repressor dimers bind to two well-separate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::466b9b2f2c69d6dc22fec26ae9c2e874
https://doi.org/10.1002/1873-3468.14447
https://doi.org/10.1002/1873-3468.14447
Autor:
Han Htoon, Vigneshwaran Chandrasekaran, Christopher DeLaney, David Parobek, Christopher Lane, Jian-Xin Zhu, Xiangzhi Li, Huan Zhao, Cong Trinh, Marshall Campbell, Andrew Jones, Matthew Schneider, John Watt, Michael Pettes, Sergei Ivanov, Andrei Piryatinski, David Dunlap
Composite quasi-particles with emergent functionalities in spintronic and quantum information science can be realized in correlated materials due to entangled charge, spin, orbital, and lattice degrees of freedom.1-3 Here we show that by reducing the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48fa85169c9641ff1ba67b71fb50f852
https://doi.org/10.21203/rs.3.rs-2769216/v1
https://doi.org/10.21203/rs.3.rs-2769216/v1
During transcription, RNA polymerases (RNAPs) must transit through roadblocks of various strengths to produce biologically meaningful transcripts. The roadblocking strength of DNA binding proteins varies significantly according to their affinity for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b810cbbf88787802f13a7573702374d
https://doi.org/10.1101/2023.01.04.522798
https://doi.org/10.1101/2023.01.04.522798
Autor:
Suparna Sarkar-Banerjee, Sachin Goyal, Ning Gao, John Mack, Benito Thompson, David Dunlap, Krishnananda Chattopadhyay, Laura Finzi
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0194930 (2018)
Genetic switches frequently include DNA loops secured by proteins. Recent studies of the lambda bacteriophage repressor (CI), showed that this arrangement in which the protein links two sets of three operators separated by approximately 2.3 kbp, opti
Externí odkaz:
https://doaj.org/article/acb0192d9ea449a792293ba11634432b
Publikováno v:
Nucleic Acids Research
Protein-mediated DNA looping is fundamental to gene regulation and such loops occur stochastically in purified systems. Additional proteins increase the probability of looping, but these probabilities maintain a broad distribution. For example, the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea92dccd6bcd560ebcb02711ab2ecae
http://europepmc.org/articles/PMC8599721
http://europepmc.org/articles/PMC8599721
Autor:
Valeria Cassina, Matteo Cristofalo, Claudia Adriana Marrano, Laura Finzi, Qing Shao, Francesco Mantegazza, Domenico Salerno, David Dunlap
Publikováno v:
Nucleic Acids Research
Single molecule experiments have demonstrated a progressive transition from a B- to an L-form helix as DNA is gently stretched and progressively unwound. The particular sequence of a DNA segment defines both base stacking and hydrogen bonding that af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518a7144d325c49e4ecb2ece3cb9832d
http://europepmc.org/articles/PMC8599871
http://europepmc.org/articles/PMC8599871
Publikováno v:
Physical Review E. 106
Transcriptional pausing is highly regulated by the template DNA and nascent transcript sequences. Here, we propose a thermodynamic model of transcriptional pausing, based on the thermal energy of transcription bubbles and nascent RNA structures, to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a2c032ca702ec0c72da102c6e03d6b9
https://doi.org/10.1103/physreve.106.044406
https://doi.org/10.1103/physreve.106.044406