Zobrazeno 1 - 10
of 16
pro vyhledávání: '"David Connors"'
Publikováno v:
Historical Methods: A Journal of Quantitative and Interdisciplinary History. 48:80-89
Researchers use a mathematical model to perform a counterfactual study of the 1854 Charge of the Light Brigade. They first calibrate the model with historical data so that it reproduces the actual charge's outcome. They then adjust the model to see h
Autor:
Alyssa N. Sbarra, David Connors, Ted Cohen, Reza Yaesoubi, Peter J White, Kara Galer, Joshua A. Salomon, Meghan Bellerose, Nicolas A Menzies, Emory E Wolf, Ibrahim Abubakar, Andrew N. Hill
Publikováno v:
e238
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Summary Mathematical modelling is commonly used to evaluate infectious disease control policy and is influential in shaping policy and budgets. Mathematical models necessarily make assumptions about disease natural history and, if these assumptions a
Autor:
Sharon Zhang, Nannon Zhou, Tao Wang, Brian McAuliffe, John F. Kadow, Louis Alexander, Michele Agler, Pin-Fang Lin, David Connors
Publikováno v:
Antimicrobial Agents and Chemotherapy. 53:4726-4732
Human immunodeficiency virus type 1 (HIV-1) envelope (Env) binding induces proapoptotic signals in CD4+T cells without a requirement of infection. Defective virus particles, which represent the majority of HIV-1, usually contain a functional Env and
Autor:
David Connors, Andrew Bullen, Lauren Barber, Christopher Bernard, Sukhanya Jayachandra, Angela Cacace
Publikováno v:
JALA: Journal of the Association for Laboratory Automation. 9:209-217
The design and implementation of an automated tissue culture flask labeling, delivery, scraping, and retrieval system centered around the CellmateTm cell culture robot is presented. Three new custom subsystems named FlaskMaster, FlaskLabeler, and Fla
Publikováno v:
Wound Repair and Regeneration. 8:292-303
We have previously shown that positively charged beads (DEAE A25) increase wound breaking strength in linear incisions in rats and nonhuman primates at days 10-14 post-wounding. The increased wound strength may result in part from a stimulation of ce
Autor:
David Connors
Publikováno v:
Daily Mail. 1/27/2023, p21. 1p.
Autor:
Edward W. Petrillo, Jeremy Stewart, John J. Herbst, Monique Anthony, David Connors, Taosheng Chen, Martyn Banks, Michele Agler
Publikováno v:
Assay and drug development technologies. 7(3)
In order to identify potential cytochrome P-450 3A4 (drug-metabolizing enzyme) inducers at an early stage of the drug discovery process, a cell-based transactivation high-throughput luciferase reporter assay for the human pregnane X receptor (PXR) in
Autor:
Yang Wu, Umesh Hanumegowda, Stephen P. Adams, Sukhanya Jayachandra, Lauren Barber, David Connors
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 23(6)
Proximal tubules of the kidneys are one of the most common targets of nephrotoxic drugs and chemicals. Screens to predict nephrotoxic potential of compounds with insights to mechanisms of toxicity facilitate lead optimization, guide structure-activit
Autor:
John J. Herbst, David Connors, Jonathan O’Connell, Martyn Banks, Anthony M. Marino, Jaime Puglisi, Michael Sinz, Jeremy Stewart, Kenneth E.J. Dickinson, Zhengrong Zhu, Angela Cacace
Publikováno v:
Journal of biomolecular screening. 12(2)
Cryopreserved, transiently transfected HepG2 cells were compared to freshly transfected HepG2 cells for use in a pregnane X receptor (PXR) transactivation assay. Assay performance was similar for both cell preparations; however, cryopreserved cells d
Autor:
Dieter Siegele, K. Nilsson, B.R. Bass, Philippe Gilles, Ulrich Eisele, David Connors, D.P.G. Lidbury, Yves Wadier, Heikki Keinänen, Kim Wallin, Elisabeth Keim, Andrew H. Sherry, Ste´phane Marie, Gerhard Nagel, D. Lauerova
Publikováno v:
Lidbury, D P G, Sherry, A H, Bass, B R, Gilles, P, Connors, D, Eisele, U, Keim, E, Keinänen, H, Wallin, K, Lauerova, D, Marie, S, Nagel, G, Nilsson, K, Siegele, D & Wadier, Y 2006, ' Validation of constraint-based methodology in structural integrity of ferritic steels for nuclear reactor pressure vessels ', Fatigue & Fracture of Engineering Materials & Structures, vol. 29, no. 9-10, pp. 829-849 . https://doi.org/10.1111/j.1460-2695.2006.01057.x
VOCALIST (validation of constraint‐based methodology in structural integrity) was a shared cost action project co‐financed by DG Research of the European Commission under the Fifth Framework of the European Atomic Energy Community (EURATOM). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad28a82bd9a573ec756154c742b86053
https://cris.vtt.fi/en/publications/06dfe5d5-73cc-44a0-b7cb-953d96c46bfa
https://cris.vtt.fi/en/publications/06dfe5d5-73cc-44a0-b7cb-953d96c46bfa