Zobrazeno 1 - 10
of 14
pro vyhledávání: '"David Číp"'
Autor:
Helena Gauani, Thomas Baker, Zhili Li, Vladimir S. Malinin, Walter Perkins, Eugene Sullivan, David Cipolla
Publikováno v:
Frontiers in Drug Delivery, Vol 2 (2022)
Treprostinil palmitil (TP) is a prodrug of treprostinil that has been formulated as an inhaled powder, termed TPIP, for evaluation in patients with pulmonary arterial hypertension. In these characterization studies we investigated the aerosol perform
Externí odkaz:
https://doaj.org/article/cfdaeee1ac7e4fb4aa9fea582832480b
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0272575 (2022)
PurposeNeutrophil serine proteases (NSPs) are implicated in numerous inflammatory diseases. Thus, a robust methodology to monitor and quantify NSPs is important to study disease progression and evaluate the effect of pharmacological interventions. A
Externí odkaz:
https://doaj.org/article/2a93b283d3564f1a9866e8426a8f046d
Autor:
Matthias Dolek, Oliver Böck, Martin Konvicka, Zdeněk Faltýnek Fric, Pavel Skala, Jana Maresova, Vladimír Hula, Miloš Andres, Tomáš Kadlec, Dana Bláhová, David Číp, Adi Geyer, Alena Sucháčková Bartoňová
Publikováno v:
Insect Systematics and Diversity. 5
Central European dry grasslands represent extrazonal patches of the Eurasian steppe biome. They suffer from severe habitat alterations due to land-use changes, abandonment, or inappropriate management. The butterflies Chazara briseis (Linnaeus, 1764)
Autor:
David Cipolla, Jimin Zhang, Brice Korkmaz, James D. Chalmers, Jessica Basso, Daniel Lasala, Carlos Fernandez, Ariel Teper, Kevin C. Mange, Walter R. Perkins, Eugene J. Sullivan
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background Brensocatib is an oral, selective, reversible inhibitor of dipeptidyl peptidase-1 (DPP-1), responsible for activating neutrophil serine proteases (NSPs) including neutrophil elastase (NE), proteinase 3 (PR3), and cathepsin G (CatG
Externí odkaz:
https://doaj.org/article/85f654da54af4f9a8406df384ca1cca2
Publikováno v:
IEEE Access, Vol 10, Pp 80833-80846 (2022)
The purpose of this manuscript is to present the Smart Driving Service (SDS), a customized mobile application, and a complex microservices framework intended not only for professional drivers but also for novel people who need help during the driving
Externí odkaz:
https://doaj.org/article/8b678dd00b6447c78ef50b75f536eb64
Autor:
Donna M. Konicek, Adam J. Plaunt, Sachin Gharse, Sasha J. Rose, Arielle Dorfman, Amruta Sabnis, Thomas Baker, Helena Gauani, Donald Chun, Zhili Li, Walter R. Perkins, David Cipolla, Vladimir S. Malinin
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2250 (2023)
The increased prevalence of pulmonary methicillin-resistant Staphylococcus aureus (MRSA) infection in patients living with cystic fibrosis (CF) is concerning due to a correlation with reduced life expectancy and lack of available treatment options. R
Externí odkaz:
https://doaj.org/article/489479d94ae3433599532bcbf80b551d
Autor:
Helena Gauani, Thomas Baker, Zhili Li, Vladimir S. Malinin, Walter R. Perkins, Eugene J. Sullivan, David Cipolla
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 934 (2023)
Treprostinil palmitil (TP), a prodrug of treprostinil, is being developed as an inhalation powder (TPIP) for the treatment of patients with pulmonary arterial hypertension (PAH) and pulmonary hypertension due to interstitial lung disease (PH-ILD). In
Externí odkaz:
https://doaj.org/article/901785b5f5b0470397f70a9f2a5e4176
Autor:
Richard W. Chapman, Michel R. Corboz, Carlos Fernandez, Eugene Sullivan, Andy Stautberg, Adam J. Plaunt, Donna M. Konicek, Vladimir Malinin, Zhili Li, David Cipolla, Walter Perkins
Publikováno v:
ERJ Open Research, Vol 7, Iss 1 (2021)
Cough is induced by inhaled prostacyclin analogues including treprostinil (TRE), and, at higher doses, treprostinil palmitil (TP), a prodrug of TRE. In this report, we have investigated mechanisms involved in TRE- and TP-induced cough, using a dry po
Externí odkaz:
https://doaj.org/article/190cdcb737b843978c4edc4c3898f89d
Autor:
Lúver Alexi Macías Jara, David Cipriano Yépez Yépez, José Ramon Chung Villavicencio, Marcos Alvarado Villegas, Adriano Rocha Galecio
Publikováno v:
Case Reports, Vol 4, Iss 1, Pp 39-45 (2018)
Introduction: Bouveret syndrome is a rare form of gallstone ileus that causes gastric obstruction due to the presence of a gallstone in the pylorus or duodenum, secondary to biliodigestive fistula. This condition is difficult to diagnose and one of i
Externí odkaz:
https://doaj.org/article/b498dfcf33e2449fa7fccfddd6ce3b5a
Autor:
David Ciplet, J. Timmons Roberts
Publikováno v:
Journal of World-Systems Research, Vol 23, Iss 2, Pp 372-398 (2017)
The article examines the changing nature of politics in the United Nations climate negotiations through the lens of ecologically unequal exchange theory, focusing on the lead up to and aftermath of the 2015 Paris negotiations. We identify and discuss
Externí odkaz:
https://doaj.org/article/37f3e69a07774856bd1b4ac63e76bdcf