Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment

Autor: Min Zhang, Jin-Li Luo, Qianqian Sun, James Harber, Alan G. Dawson, Apostolos Nakas, Sara Busacca, Annabel J. Sharkey, David Waller, Michael T. Sheaff, Cathy Richards, Peter Wells-Jordan, Aarti Gaba, Charlotte Poile, Essa Y. Baitei, Aleksandra Bzura, Joanna Dzialo, Maymun Jama, John Le Quesne, Amrita Bajaj, Luke Martison, Jacqui A. Shaw, Catrin Pritchard, Tamihiro Kamata, Nathaniel Kuse, Lee Brannan, Pan De Philip Zhang, Hongji Yang, Gareth Griffiths, Gareth Wilson, Charles Swanton, Frank Dudbridge, Edward J. Hollox, Dean A. Fennell

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

The impact of intratumour heterogeneity on immune surveillance and clinical outcomes has not been adequately explored in malignant pleural mesothelioma (MPM). Here the authors analyse the influence of evolution on the survival and immune landscape of

Externí odkaz: https://doaj.org/article/341b50055bdd45939a6f7909af185de3

Maintaining safe lung cancer surgery during the COVID-19 pandemic in a global city

Autor: Stephanie Fraser, Ralitsa Baranowski, Davide Patrini, Jay Nandi, May Al-Sahaf, Jeremy Smelt, Ross Hoffman, Gowthanan Santhirakumaran, Michelle Lee, Anuj Wali, Harvey Dickinson, Mehmood Jadoon, Karen Harrison-Phipps, Juliet King, John Pilling, Andrea Bille, Lawrence Okiror, Sasha Stamenkovic, David Waller, Henrietta Wilson, Simon Jordan, Sofina Begum, Silviu Buderi, Carol Tan, Ian Hunt, Paul Vaughan, Melanie Jenkins, Martin Hayward, David Lawrence, Emma Beddow, Vladimir Anikin, Aleksander Mani, Jonathan Finch, Hendramoorthy Maheswaran, Eric Lim, Tom Routledge, Kelvin Lau, Leanne Harling

Publikováno v: EClinicalMedicine, Vol 39, Iss , Pp 101085- (2021)

Background: SARS-CoV-2 has challenged health service provision worldwide. This work evaluates safe surgical pathways and standard operating procedures implemented in the high volume, global city of London during the first wave of SARS-CoV-2 infection

Externí odkaz: https://doaj.org/article/ea57409689524e0b8c9e7c5f8ba1f1d0

Mesothelioma and Radical Surgery 2 (MARS 2): protocol for a multicentre randomised trial comparing (extended) pleurectomy decortication versus no (extended) pleurectomy decortication for patients with malignant pleural mesothelioma

Autor: Liz Darlison, Apostolos Nakas, Wendy Underwood, Matthew Callister, David Waller, Richard Milton, Victoria Ashford-Turner, Paul Taylor, Claire Matthews, Victoria Hughes, Kelvin Lau, Alan Kirk, Robert C Rintoul, Elizabeth A Stokes, Kate Ashton, Daisy Elliott, Rosie Harris, Marie Kirwan, Juliette Novasio, Sara Waplington, Eric Lim, Holly Mckeon, Charlotte Jacobs, Laura White, Mary O’Brien, Judith Moore, Louise Li, Nicola Mills, Sanjay Popat, Suzanne Miller, Nadia Yousaf, D A Fennell, Clinton Ali, Andrea Bille, Liz Fuller, Andreea Ionescu, Manjusha Keni, Pek Koh, Talal Mansy, Dakshinamoorthy Muthukumar, Tony Pope, Amy Roy, Riyaz Shah, Jonathan Shamash, Zacharias Tasigiannopoulos, Sarah Treece, Katherine Joyce, Barbara Warnes, Athanasia Gravani, Rachel Brophy, Nicola Farrar, Jane Elliott, Philip Noyes, Louise Nelson, Sara Tenconi, Laura Socci, Hilary Wood, Helena Hanratty, Helena Stanley, Robert Rintoul, Amy Gladwell, Jenny Castedo, Amanda Stone, Charlotte Ingle, Hayley Hewer, Eleanor Aynsley, Andrea Watson, Alison Hassall, Masuma Begum, Christopher Worth, Ellie Piggott, Elizabeth Nadin, Yvonne Summers, Raffaele Califano, Laura Cove-Smith, Matt Evison, Maria Blinston, Amal Ismail, Rachel Chant, Asmita Desai, Ian Morgan, Victoria Lake, Nichola Harris, Simon Hodge, Nadza Tokaca, Adam Januszewski, Avani Athauda, Anisha Ramessur, Emily Grist, Niamh Colman, Michael Flynn, Joan Joyce, Sarah Vaughan, Maria Piga, Derya Sahin, Agnieszka Yongue, Emma Turay, Jaishree Bhosle, Rajiv Kumar, Charlotte Milner-Watts, Jessica Brown, David Walder, Alexandros Georgiou, Xiaorong Wu, Naila Kaudeer, Kroopa Joshi, Michael Davidson, Shelize Khakoo, Bee Ayite, Kathryn Priest, James Dobbyn, Vasanthi Prathapan, Deborah McCrimmon, Natalie Ash, Alison Norton, Bianca Peet, Libby Hennessy, Rosemary Johnson

Publikováno v: BMJ Open, Vol 10, Iss 9 (2020)

Introduction Mesothelioma remains a lethal cancer. To date, systemic therapy with pemetrexed and a platinum drug remains the only licensed standard of care. As the median survival for patients with mesothelioma is 12.1 months, surgery is an important

Externí odkaz: https://doaj.org/article/32fc85f80c044e6eb4476952c3c0a85c

A new endemic species of Chicoreus from Savai’l, Samoa

Autor: David Berschauer, David Waller, Stephen Maxwell

Publikováno v: The Festivus. 54:21-28

A new species of Muricidae, Chicoreus (Triplex) tangaroai is described from the Samoan Infraprovince. This new taxa is compared with C. (T.) thomasi (Crosse, 1872) and C. (T.) lorenzi Houart, 2009, related species in the Marquesan Molluscan Province.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0cc30a71dbe98ab8c0f30ccd98d84926
https://doi.org/10.54173/f54121

Pt-Catchment Using Pd/Au Alloys: Effect of Enhanced Diffusion

Autor: Asbjørn Slagtern Fjellvåg, David Waller, Thomas By, Anja Olafsen Sjåstad

We have studied a series of Pd/Au alloys as Pt-catchment materials, both in lab-scale experiments and in an industrial ammonia oxidation plant. Our focus has been on how bulk Pt diffusion affects grain reconstruction in Pd/Au alloys (91/9 and 50/50 a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88031746f7abbe86ddc3cf58a15b61db
http://hdl.handle.net/10852/101564