Zobrazeno 1 - 10
of 30
pro vyhledávání: '"David, Větvička"'
Autor:
Oleksandr Shapoval, David Větvička, Vitalii Patsula, Hana Engstová, Olga Kočková, Magdalena Konefał, Martina Kabešová, Daniel Horák
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2694 (2023)
Upconverting nanoparticles are interesting materials that have the potential for use in many applications ranging from solar energy harvesting to biosensing, light-triggered drug delivery, and photodynamic therapy (PDT). One of the main requirements
Externí odkaz:
https://doaj.org/article/ca0118b4ed0e4282a1becdb4e162fe5a
Autor:
Robert Pola, Eliška Böhmová, Marcela Filipová, Michal Pechar, Jan Pankrác, David Větvička, Tomáš Olejár, Martina Kabešová, Pavla Poučková, Luděk Šefc, Michal Zábrodský, Olga Janoušková, Jan Bouček, Tomáš Etrych
Publikováno v:
Pharmaceutics, Vol 12, Iss 1, p 31 (2020)
This report describes the design, synthesis and evaluation of tumor-targeted polymer probes to visualize epidermal growth factor receptor (EGFR)-positive malignant tumors for successful resection via fluorescence guided endoscopic surgery. Fluorescen
Externí odkaz:
https://doaj.org/article/913f058206dd4cfaa7155126fd21ca6c
Autor:
David Oupický, Ying Xie, Fei Yu, Weimin Tang, Siyuan Tang, Diptesh Sil, Jing Li, Rakesh K. Singh, David Větvička, Ao Yu, Chuhan Zhang, Yu Hang
Publikováno v:
J Control Release
Pancreatic ductal adenocarcinoma (PDAC) is a growing medical problem associated with extensive metastasis and high mortality. Intraperitoneal (IP) administration of therapeutics promises to help the treatment of cancers originated from organs in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20cd867e1d0b51d64fb50b0b51b9ad68
https://europepmc.org/articles/PMC8122076/
https://europepmc.org/articles/PMC8122076/
Autor:
Lenka Poláková, Vladimír Raus, Lucie Cuchalová, Rafał Poręba, Martin Hrubý, Jan Kučka, David Větvička, Olga Trhlíková, Zdeňka Sedláková
Publikováno v:
International Journal of Pharmaceutics. 613:121392
Inflammatory bowel disease (IBD) is a relapsing and remitting inflammatory disease affecting millions of people worldwide. The active phase of IBD is characterized by excessive formation of reactive oxygen species (ROS) in the intestinal mucosa, whic
Autor:
Jan Pankrác, Michal Zábrodský, Jan Bouček, Eliška Böhmová, Robert Pola, Olga Janoušková, David Větvička, Tomáš Olejár, Luděk Šefc, Michal Pechar, Tomáš Etrych, Martina Kabešová, Marcela Filipová, Pavla Pouckova
Publikováno v:
Pharmaceutics
Volume 12
Issue 1
Pharmaceutics, Vol 12, Iss 1, p 31 (2020)
Volume 12
Issue 1
Pharmaceutics, Vol 12, Iss 1, p 31 (2020)
This report describes the design, synthesis and evaluation of tumor-targeted polymer probes to visualize epidermal growth factor receptor (EGFR)-positive malignant tumors for successful resection via fluorescence guided endoscopic surgery. Fluorescen
Autor:
Uliana Kostiv, David Větvička, Agnieszka Noculak, Artur Podhorodecki, Zdenka Sedlakova, Daniel Horák, Pavla Pouckova, Vitalii Patsula
Publikováno v:
ChemMedChem. 12:2066-2073
Photodynamic therapy (PDT) has garnered immense attention as a minimally invasive clinical treatment modality for malignant cancers. However, its low penetration depth and photodamage of living tissues by UV and visible light, which activate a photos
Biochemical Background in Mitochondria Affects 2HG Production by IDH2 and ADHFE1 in Breast Carcinoma
Autor:
Jitka Špačková, Petr Ježek, Libor Vítek, Alexandra Urbančoková, Petra Tesařová, Katarína Smolková, Kateřina Pospíšilová, David Větvička, Alberto Leguina-Ruzzi, Klára Gotvaldová, Aleš Dvořák
Publikováno v:
Cancers
Volume 13
Issue 7
Cancers, Vol 13, Iss 1709, p 1709 (2021)
Volume 13
Issue 7
Cancers, Vol 13, Iss 1709, p 1709 (2021)
Simple Summary 2-hydroxyglutarate (2HG) is a metabolite resembling normal cell metabolite 2-oxoglutarate (2OG), however, its accumulation in cells might lead to amplification of processes in cancer development. R-2HG is a product or bi-product of sev
Autor:
Jan Pankrác, Pavel Trefil, Robert Pola, K Zuska, Ludek Sefc, Pavla Pouckova, Jan Bouček, Olga Janoušková, Jiří Kalina, Eliška Böhmová, Michal Pechar, Tomáš Etrych, J. Mucksová, David Větvička, Jozef Parnica, Marcela Filipová
Publikováno v:
Multifunctional Materials. 2:024004
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:5669-5672
Polymer conjugates of anticancer drugs have shown high potential for assisting in cancer treatments. The pH-labile spacers allow site-specific triggered release of the drugs. We synthesized and characterized model drug conjugates with hydrazide bond-
Autor:
Martin Hrubý, Ondřej Sedláček, Martin Studenovský, Jan Kovář, Karel Ulbrich, David Větvička, Jan Svoboda, Dana Kaňková
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:4056-4063
Acridines are potent DNA-intercalating anticancer agents with high in vivo anticancer effectiveness, but also severe side effects. We synthesized five 9-anilinoacridine-type drugs and their conjugates with biocompatible water-soluble hydrazide polyme