Zobrazeno 1 - 10
of 63
pro vyhledávání: '"David, Shorthouse"'
Autor:
Andrea Weeks, Elizabeth Collins, Twanelle Majors, Zack Murrell, Deborah Paul, Matthew Sheik, David Shorthouse, Shawn Zeringue-Krosnick
Publikováno v:
Research Ideas and Outcomes, Vol 10, Iss , Pp 1-18 (2024)
We created and delivered a workshop and symposium series for biologists at all career stages focused on the skills and practices needed to sustain natural history specimen attribution and citation. The name of the workshop and symposium series, SISRI
Externí odkaz:
https://doaj.org/article/7b79ca4e49c14a5f8609f3dbcd38ebe2
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract Highly sensitive DNA sequencing techniques have allowed the discovery of large numbers of somatic mutations in normal tissues. Some mutations confer a competitive advantage over wild-type cells, generating expanding clones that spread throug
Externí odkaz:
https://doaj.org/article/5502ff1cc7eb4d59948e2b563cac925f
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 11, Pp 1-15 (2022)
Abstract The unravelling of the complexity of cellular metabolism is in its infancy. Cancer‐associated genetic alterations may result in changes to cellular metabolism that aid in understanding phenotypic changes, reveal detectable metabolic signat
Externí odkaz:
https://doaj.org/article/0313cb9805bf4769a4632f9cd173f143
Autor:
Laure Talarmain, Matthew A. Clarke, David Shorthouse, Lilia Cabrera-Cosme, David G. Kent, Jasmin Fisher, Benjamin A. Hall
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
HOXA9 plays an important role in acute myeloid leukaemia (AML), but its relevance for other blood malignancies is unclear. Here, the authors show that HOXA9 has a binary switch function that can clinically stratify AML patients, and model how the int
Externí odkaz:
https://doaj.org/article/5dbdffc27b334b189ae56094325547a0
Autor:
Quentin Groom, Christian Bräuchler, Robert Cubey, Mathias Dillen, Pieter Huybrechts, Nicole Kearney, Niels Klazenga, Siobhan Leachman, Deborah L Paul, Heather Rogers, Joaquim Santos, David Shorthouse, Alison Vaughan, Sabine von Mering, Elspeth Haston
Publikováno v:
Biodiversity Data Journal, Vol 10, Iss , Pp 1-37 (2022)
Scientific collections have been built by people. For hundreds of years, people have collected, studied, identified, preserved, documented and curated collection specimens. Understanding who those people are is of interest to historians, but much mor
Externí odkaz:
https://doaj.org/article/468ec405ff4c4619aa6fec3955dcff15
Autor:
David Shorthouse, Angela Riedel, Emma Kerr, Luisa Pedro, Dóra Bihary, Shamith Samarajiwa, Carla P. Martins, Jacqueline Shields, Benjamin A. Hall
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Aberrant ion transporter expression disrupts osmoregulation in many cancers. Here, the authors introduce an executable model of osmotic regulation and membrane transport, illuminating the mechanistic basis of multiple cellular cancer phenotypes and s
Externí odkaz:
https://doaj.org/article/da32886ecfdc4f129d741fa8e63bc987
Autor:
Jacqueline D. Shields, Thordur Oskarsson, Christian Frezza, Benjamin A. Hall, Elmar Wolf, Pranjali Bhandare, Sarah Davidson, Ana S.H. da Costa, Timothy Young, Lisa Haas, Werner Schmitz, David Shorthouse, Jonathan J. Swietlik, Luisa Pedro, Moutaz Helal, Angela Riedel
Supplementary Figure from Tumor-Derived Lactic Acid Modulates Activation and Metabolic Status of Draining Lymph Node Stroma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28152e72cb1e3c652b1652559f63c755
https://doi.org/10.1158/2326-6066.22544688
https://doi.org/10.1158/2326-6066.22544688
Autor:
Jacqueline D. Shields, Thordur Oskarsson, Christian Frezza, Benjamin A. Hall, Elmar Wolf, Pranjali Bhandare, Sarah Davidson, Ana S.H. da Costa, Timothy Young, Lisa Haas, Werner Schmitz, David Shorthouse, Jonathan J. Swietlik, Luisa Pedro, Moutaz Helal, Angela Riedel
Communication between tumors and the stroma of tumor-draining lymph nodes (TDLN) exists before metastasis arises, altering the structure and function of the TDLN niche. Transcriptional profiling of fibroblastic reticular cells (FRC), the dominant str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d68742aaf315adb8d0db165ccf50928
https://doi.org/10.1158/2326-6066.c.6550725.v1
https://doi.org/10.1158/2326-6066.c.6550725.v1
Autor:
Philip H. Jones, Moritz Gerstung, Benjamin A. Hall, Kourosh Saeb-Parsy, Krishnaa Mahububani, Amit Roshan, Doreen Milne, Edward Rytina, Kate Fife, Amer Durrani, David Shorthouse, Stefan C. Dentro, Jonas Koeppel, David Fernandez-Antoran, Eleanor Earp, Swee Hoe Ong, Roshan Sood, Michael W.J. Hall, Christopher Bryant, Charlotte King, Joanna C. Fowler
Supplementary Figures S1-S7 and Tables S1 and S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da2713af077ae5bc61eaf6263b393c1
https://doi.org/10.1158/2159-8290.22536427
https://doi.org/10.1158/2159-8290.22536427
Autor:
Philip H. Jones, Moritz Gerstung, Benjamin A. Hall, Kourosh Saeb-Parsy, Krishnaa Mahububani, Amit Roshan, Doreen Milne, Edward Rytina, Kate Fife, Amer Durrani, David Shorthouse, Stefan C. Dentro, Jonas Koeppel, David Fernandez-Antoran, Eleanor Earp, Swee Hoe Ong, Roshan Sood, Michael W.J. Hall, Christopher Bryant, Charlotte King, Joanna C. Fowler
Skin cancer risk varies substantially across the body, yet how this relates to the mutations found in normal skin is unknown. Here we mapped mutant clones in skin from high- and low-risk sites. The density of mutations varied by location. The prevale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92b0c0c529c6f7cf94e8235bbfd78975
https://doi.org/10.1158/2159-8290.c.6548143.v1
https://doi.org/10.1158/2159-8290.c.6548143.v1