Zobrazeno 1 - 10
of 199
pro vyhledávání: '"David, Sacks"'
Autor:
Devi Parvathy Jyothi Ramachandran Nair, Shilla Zachariah, Anisha Abraham, David Sacks, Michael Koslow, Rittu Hingorani
Publikováno v:
European Journal of Case Reports in Internal Medicine (2024)
Anomalous bronchial artery origins may have clinical implications beyond their anatomical curiosity. In this case, the identification of such an anomaly led to the diagnosis of chronic thromboembolic pulmonary hypertension (CTEPH). A 49-year-old male
Externí odkaz:
https://doaj.org/article/c3c4daeff46b4a01a9c161eba81d6fea
Autor:
Carolina Moura Costa Catta-Preta, Tiago Rodrigues Ferreira, Kashinath Ghosh, Andrea Paun, David Sacks
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Whole genome analysis of Leishmania hybrids generated experimentally in sand flies supports a meiotic mechanism of genetic exchange, with Mendelian segregation of the nuclear genome. Here, we perform functional analyses through the generatio
Externí odkaz:
https://doaj.org/article/96607c1c481c491b9be8ed941a6c75e8
Autor:
Jeff Slezak, David Sacks, Vicki Chiu, Chantal Avila, Nehaa Khadka, Jiu-Chiuan Chen, Jun Wu, Darios Getahun
Publikováno v:
JMIR Medical Informatics, Vol 11, p e43005 (2023)
BackgroundThe accuracy of electronic health records (EHRs) for identifying postpartum depression (PPD) is not well studied. ObjectiveThis study aims to evaluate the accuracy of PPD reporting in EHRs and compare the quality of PPD data collected befo
Externí odkaz:
https://doaj.org/article/9f1f5637d82442cdbb7f3618f2725182
Autor:
Tiago R. Ferreira, Ehud Inbar, Jahangheer Shaik, Brendan M. Jeffrey, Kashinath Ghosh, Deborah E. Dobson, Stephen M. Beverley, David Sacks
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Genetic exchange between different Leishmania strains in the sand fly vector has been experimentally demonstrated and is supported by population genetic studies. In nature, opportunities for Leishmania interstrain mating are restricted to fl
Externí odkaz:
https://doaj.org/article/e411654cf8044b90ba50e2c8e4780d56
Autor:
Isabelle Louradour, Tiago Rodrigues Ferreira, Emma Duge, Nadira Karunaweera, Andrea Paun, David Sacks
Publikováno v:
eLife, Vol 11 (2022)
Leishmania are protozoan parasites transmitted by the bite of sand fly vectors producing a wide spectrum of diseases in their mammalian hosts. These diverse clinical outcomes are directly associated with parasite strain and species diversity. Althoug
Externí odkaz:
https://doaj.org/article/7273961b5f8b4da88e2c63e92654586d
Autor:
Mateus Eustáquio Lopes, Liliane Martins dos Santos, David Sacks, Leda Quercia Vieira, Matheus B. Carneiro
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Innate immune cells present a dual role during leishmaniasis: they constitute the first line of host defense but are also the main host cells for the parasite. Response against the infection that results in the control of parasite growth and lesion h
Externí odkaz:
https://doaj.org/article/108bcb624ec9450da561f525e83f3a23
Autor:
Francis J. Jareczek, Mary Beth Farrell, Erik B. Lehman, Cathy Sila, John B. Terry, David Sacks, Paul Kalapos, Scott D. Simon, Kevin M. Cockroft
Publikováno v:
Stroke. 54:1578-1586
Background: Based on the inclusion criteria of clinical trials, the degree of cervical carotid artery stenosis is often used as an indication for stent placement in the setting of extracranial carotid atherosclerotic disease. However, the rigor and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96f21a5c57f9d8a06cd88823c9749829
https://doi.org/10.1161/strokeaha.122.041397
https://doi.org/10.1161/strokeaha.122.041397
Autor:
Mariana M Chaves, Sang Hun Lee, Olena Kamenyeva, Kashinath Ghosh, Nathan C Peters, David Sacks
Publikováno v:
PLoS Pathogens, Vol 16, Iss 11, p e1008674 (2020)
There is substantial experimental evidence to indicate that Leishmania infections that are transmitted naturally by the bites of infected sand flies differ in fundamental ways from those initiated by needle inocula. We have used flow cytometry and in
Externí odkaz:
https://doaj.org/article/1a69aa6409b84cf2be0081efe18f345c
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 8, p e0008363 (2020)
Visceral leishmaniasis (VL) remains an important public health issue worldwide causing substantial morbidity and mortality. The Indian subcontinent accounted for up to 90% of the global VL burden in the past but made significant progress during recen
Externí odkaz:
https://doaj.org/article/d3d83863efef47d39b84f0b8a75db845
Autor:
Rajiv Kumar, Patrick T. Bunn, Siddharth Sankar Singh, Susanna S. Ng, Marcela Montes de Oca, Fabian De Labastida Rivera, Shashi Bhushan Chauhan, Neetu Singh, Rebecca J. Faleiro, Chelsea L. Edwards, Teija C.M. Frame, Meru Sheel, Rebecca J. Austin, Steven W. Lane, Tobias Bald, Mark J. Smyth, Geoffrey.R. Hill, Shannon E. Best, Ashraful Haque, Dillon Corvino, Nic Waddell, Lambross Koufariotis, Pamela Mukhopadhay, Madhukar Rai, Jaya Chakravarty, Om Prakash Singh, David Sacks, Susanne Nylen, Jude Uzonna, Shyam Sundar, Christian R. Engwerda
Publikováno v:
Cell Reports, Vol 30, Iss 8, Pp 2512-2525.e9 (2020)
Summary: Type I interferons (IFNs) play critical roles in anti-viral and anti-tumor immunity. However, they also suppress protective immune responses in some infectious diseases. Here, we identify type I IFNs as major upstream regulators of CD4+ T ce
Externí odkaz:
https://doaj.org/article/e785a439bde64e73885e903f52fe0682