Zobrazeno 1 - 10
of 53
pro vyhledávání: '"David, Requena"'
Autor:
Gabriel Jiménez-Avalos, Alina Soto-Obando, Maria Solis, Robert H. Gilman, Vitaliano Cama, Armando E. Gonzalez, Hector H. García, Patricia Sheen, David Requena, Mirko Zimic, for the Cysticercosis Working Group in Peru
Publikováno v:
Parasites & Vectors, Vol 16, Iss 1, Pp 1-14 (2023)
Abstract Background Taenia solium is a parasite of public health concern, causing human taeniasis and cysticercosis. Two main genotypes have been identified: Asian and African-American. Although characterizing T. solium genotypes is crucial to unders
Externí odkaz:
https://doaj.org/article/79074fa6784f4dafb90840721fd3b940
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0309352 (2024)
Pyrazinamide (PZA) is a key drug in the treatment of Mycobacterium tuberculosis. Although not completely understood yet, the bactericidal mechanism of PZA starts with its diffusion into the cell and subsequent conversion into pyrazinoic acid (POA) af
Externí odkaz:
https://doaj.org/article/161099cba93d42459533ea1bdd2fffdb
Autor:
Luis F. Soto, Ana C. Romaní, Gabriel Jiménez-Avalos, Yshoner Silva, Carla M. Ordinola-Ramirez, Rainer M. Lopez Lapa, David Requena
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Clostridium perfringens is a dangerous bacterium and known biological warfare weapon associated with several diseases, whose lethal toxins can produce necrosis in humans. However, there is no safe and fully effective vaccine against C. perfringens fo
Externí odkaz:
https://doaj.org/article/38bba288928442c5a5e69bd7d81a055f
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0273577 (2022)
Multiple immunoinformatic tools have been developed to predict T-cell epitopes from protein amino acid sequences for different major histocompatibility complex (MHC) alleles. These prediction tools output hundreds of potential peptide candidates whic
Externí odkaz:
https://doaj.org/article/d3c47ee09c814f59ae38f14d80e39eac
Autor:
Sandra Morales Ruiz, Jorge Bendezu, Ricardo Choque Guevara, Ricardo Montesinos, David Requena, Luz Choque Moreau, Ángela Montalván Ávalos, Manolo Fernández-Díaz
Publikováno v:
BMC Veterinary Research, Vol 14, Iss 1, Pp 1-15 (2018)
Abstract Background Infectious coryza (IC) is an acute respiratory disease of growing chickens and layers caused by Avibacterium paragallinarum. The development of tools that allow rapid pathogen detection is necessary in order to avoid disease disse
Externí odkaz:
https://doaj.org/article/4e6e12ee8ba744f78722fac239bd1d3b
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Coronavirus disease (COVID-19), caused by the virus SARS-CoV-2, is already responsible for more than 4.3 million confirmed cases and 295,000 deaths worldwide as of May 15, 2020. Ongoing efforts to control the pandemic include the development of pepti
Externí odkaz:
https://doaj.org/article/8adbcb5795f34a3db7a288186b25642e
Autor:
Daniel Rueda, Roberto Furukawa, Patricia Fuentes, Germán Comina, Nicolás G Rey De Castro, David Requena, Robert H Gilman, Patricia Sheen, Mirko Zimic
Publikováno v:
International Journal of Mycobacteriology, Vol 7, Iss 3, Pp 275-281 (2018)
Introduction: Tuberculosis (TB) is a significant cause of morbidity and mortality worldwide. The patient compliance with the long treatment regimens is essential for successful eradication. Pyrazinamide (PZA) shortens these regimens from 9 to 6 month
Externí odkaz:
https://doaj.org/article/69fb1dadb4fe445a837116e3f0a5020b
Autor:
Patricia Sheen, David Requena, Eduardo Gushiken, Robert H. Gilman, Ricardo Antiparra, Bryan Lucero, Pilar Lizárraga, Basilio Cieza, Elisa Roncal, Louis Grandjean, Arnab Pain, Ruth McNerney, Taane G. Clark, David Moore, Mirko Zimic
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background Tuberculosis (TB) is a major global health problem and drug resistance compromises the efforts to control this disease. Pyrazinamide (PZA) is an important drug used in both first and second line treatment regimes. However, its com
Externí odkaz:
https://doaj.org/article/e2489c00d5ae491da6a99492cd163f2f
Autor:
Sanford M. Simon, Michael V. Ortiz, Michael S. Torbenson, Philip Coffino, Anthony Letai, Charles M. Rice, Michael P. LaQuaglia, Hans-Guido Wendel, Tomoaki Kato, Faith Tierney, Rory L. Smoot, Mark J. Truty, Jennifer L. Leiting, Martin Hertl, Erik Schadde, Jessica Ellison, Barbara A. Lyons, J. Fraser Glickman, Ethan M. Weinberg, James A. Saltsman, William J. Hammond, Benjamin A. Farber, Arlene M. Hurley, Koen O.A. Vercauteren, Mohammad Kabbani, Eleftherios Michailidis, Solomon Levin, Bassem Shebl, Nicole J.C. Narayan, Ruisi Wang, Ype P. de Jong, Patrick D. Bhola, Denise Ng, Lavoisier Ramos-Espiritu, David Requena, Gadi Lalazar
To repurpose therapeutics for fibrolamellar carcinoma (FLC), we developed and validated patient-derived xenografts (PDX) from surgical resections. Most agents used clinically and inhibitors of oncogenes overexpressed in FLC showed little efficacy on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b2e6eadd89b35c3fbc11103d986522f
https://doi.org/10.1158/2159-8290.c.6549037.v1
https://doi.org/10.1158/2159-8290.c.6549037.v1
Autor:
Sanford M. Simon, Michael V. Ortiz, Michael S. Torbenson, Philip Coffino, Anthony Letai, Charles M. Rice, Michael P. LaQuaglia, Hans-Guido Wendel, Tomoaki Kato, Faith Tierney, Rory L. Smoot, Mark J. Truty, Jennifer L. Leiting, Martin Hertl, Erik Schadde, Jessica Ellison, Barbara A. Lyons, J. Fraser Glickman, Ethan M. Weinberg, James A. Saltsman, William J. Hammond, Benjamin A. Farber, Arlene M. Hurley, Koen O.A. Vercauteren, Mohammad Kabbani, Eleftherios Michailidis, Solomon Levin, Bassem Shebl, Nicole J.C. Narayan, Ruisi Wang, Ype P. de Jong, Patrick D. Bhola, Denise Ng, Lavoisier Ramos-Espiritu, David Requena, Gadi Lalazar
Supplementary Figure 1 - 6 and Supplementary Tables 1, 2, and 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b902995a0b627ef4461c460e313fed
https://doi.org/10.1158/2159-8290.22539256
https://doi.org/10.1158/2159-8290.22539256