Zobrazeno 1 - 10
of 44
pro vyhledávání: '"David, Reigada"'
Autor:
Altea Soto, Manuel Nieto-Díaz, Enrique Martínez-Campos, Ana Noalles-Dols, María Asunción Barreda-Manso, Felipe Reviriego, Helmut Reinecke, David Reigada, Teresa Muñoz-Galdeano, Irene Novillo, Alberto Gallardo, Juan Rodríguez-Hernández, Ramón Eritja, Anna Aviñó, Carlos Elvira, Rodrigo M. Maza
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1451 (2023)
MicroRNAs (miRNAs) are endogenous, short RNA oligonucleotides that regulate the expression of hundreds of proteins to control cells’ function in physiological and pathological conditions. miRNA therapeutics are highly specific, reducing the toxicit
Externí odkaz:
https://doaj.org/article/6e336ec2b6154f558aa9aad96f96bacf
Autor:
Rodrigo M. Maza, María Asunción Barreda-Manso, David Reigada, Ágata Silván, Teresa Muñoz-Galdeano, Altea Soto, Ángela del Águila, Manuel Nieto-Díaz
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1559 (2022)
The central nervous system microRNA miR-138-5p has attracted much attention in cancer research because it inhibits pro-apoptotic genes including CASP3. We hypothesize that miR-138-5p downregulation after SCI leads to overexpression of pro-apoptotic g
Externí odkaz:
https://doaj.org/article/bc7faf3326e64ae2b14a8c259184571d
Autor:
Altea Soto, Manuel Nieto-Díaz, David Reigada, María Asunción Barreda-Manso, Teresa Muñoz-Galdeano, Rodrigo M. Maza
Publikováno v:
Pharmaceuticals, Vol 15, Iss 5, p 529 (2022)
Nogo-A protein is a key myelin-associated inhibitor of axonal growth, regeneration, and plasticity in the central nervous system (CNS). Regulation of the Nogo-A/NgR1 pathway facilitates functional recovery and neural repair after spinal cord trauma a
Externí odkaz:
https://doaj.org/article/bdfc995ec6bb47528b13b7003a2c6f94
Autor:
Teresa Muñoz-Galdeano, David Reigada, Ángela del Águila, Irene Velez, Marcos J. Caballero-López, Rodrigo M. Maza, Manuel Nieto-Díaz
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Autophagy is an essential process of cellular waist clearance that becomes altered following spinal cord injury (SCI). Details on these changes, including timing after injury, underlying mechanisms, and affected cells, remain controversial. Here we p
Externí odkaz:
https://doaj.org/article/8022337ce196416ca50a99b29d4db6e3
Autor:
Teresa Muñoz-Galdeano, David Reigada, María Gamarra, Altea Soto, María Asunción Barreda-Manso, Irene Novillo, Manuel Nieto-Díaz, Rodrigo M. Maza
Altered expression of microRNAs (miRNAs) after spinal cord injury (SCI) has been described as being responsible for the main secondary responses, such as apoptosis. X-linked inhibitor apoptosis protein (XIAP) is a key apoptotic component involved in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee92c73c71f04d94685ce86cd4230d6
Autor:
David Reigada, Rodrigo M. Maza, Teresa Muñoz-Galdeano, María Asunción Barreda-Manso, Altea Soto, Dan Lindholm, Rosa Navarro-Ruíz, Manuel Nieto-Díaz
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2791
Volume 24
Issue 3
Pages: 2791
Mechanical trauma to the spinal cord causes extensive neuronal death, contributing to the loss of sensory-motor and autonomic functions below the injury location. Apoptosis affects neurons after spinal cord injury (SCI) and is associated with increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf4da330071ec4b8cbcfb29233f1886
https://doi.org/10.20944/preprints202212.0023.v1
https://doi.org/10.20944/preprints202212.0023.v1
Autor:
M. Asunción Barreda-Manso, Altea Soto, Teresa Muñoz-Galdeano, David Reigada, Manuel Nieto-Díaz, Rodrigo M. Maza
Neuronal maturation is a process that plays a key role in the development and regeneration of the central nervous system. Although embryonic brain development and neurodegeneration have received considerable attention, the events that govern postnata
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e25b3cc99a703191cd75117186f47e4b
https://doi.org/10.1101/2022.11.15.516547
https://doi.org/10.1101/2022.11.15.516547
Autor:
David Reigada, Vanesa Soto, María González-Rodríguez, María Asunción Barreda-Manso, Altea Soto, Teresa Muñoz-Galdeano, Rodrigo M. Maza, Manuel Nieto-Díaz
Spinal cord injury (SCI) is a major cause of permanent disability and its causes and pathophysiological effects are very variables between patients. The assessment of tissue damage extent and neurodegeneration degree correlated with the functional ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d024e6c5205f57aa4762f524fea2b0a0
https://doi.org/10.1101/2022.05.05.490720
https://doi.org/10.1101/2022.05.05.490720
Autor:
Andrés Ángel Calderón-García, Manuel Nieto-Díaz, Teresa Muñoz-Galdeano, Rodrigo M. Maza, David Reigada, Manuel Soto‐Catalán, Ángela del Águila
Publikováno v:
Journal of Neurochemistry. 151:116-130
Excitotoxic cell death because of the massive release of glutamate and ATP contributes to the secondary extension of cellular and tissue loss following traumatic spinal cord injury (SCI). Evidence from blockage experiments suggests that over-expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed3cc691535694eb30c8e7e4dfde67e7
https://doi.org/10.1111/jnc.14700
https://doi.org/10.1111/jnc.14700
Autor:
David Reigada, Altea Soto, Teresa Muñoz-Galdeano, Rodrigo M. Maza, María Asunción Barreda-Manso, Manuel Nieto-Díaz
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 6094, p 6094 (2021)
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 6094, p 6094 (2021)
COVID-19 pandemic is caused by betacoronavirus SARS-CoV-2. The genome of this virus is composed of a single strand of RNA with 5′ and 3′-UTR flanking a region of protein-coding ORFs closely resembling cells’ mRNAs. MicroRNAs are endogenous post
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3016a22fa46e9330f7b86c8e4995cf