Zobrazeno 1 - 10
of 31
pro vyhledávání: '"David, Razafsky"'
Autor:
Corey Kretzmer, Kelsey Reger, Vincent Balassi, Quang Long Pham, Michael Johns, Samuel T. Peters, Amber Petersen, Jana Mahadevan, Jason Gustin, Trissa Borgschulte, David Razafsky
Publikováno v:
Cells, Vol 12, Iss 22, p 2661 (2023)
Chinese hamster ovary (CHO) cells are the cell line of choice for producing recombinant therapeutic proteins. Despite improvements in production processes, reducing manufacturing costs remains a key driver in the search for more productive clones. To
Externí odkaz:
https://doaj.org/article/501a38e3e6c840889fb116e374248046
Autor:
Corey Kretzmer, Rajagopalan Lakshmi Narasimhan, Rahul Deva Lal, Vincent Balassi, James Ravellette, Ajaya Kumar Kotekar Manjunath, Jesvin Joy Koshy, Marta Viano, Serena Torre, Valeria M. Zanda, Mausam Kumravat, Keith Metelo Raul Saldanha, Harikrishnan Chandranpillai, Ifra Nihad, Fei Zhong, Yi Sun, Jason Gustin, Trissa Borgschulte, Jiajian Liu, David Razafsky
Publikováno v:
Biotechnology and Bioengineering. 119:3632-3646
Autor:
Yunlu Xue, Shinya Sato, David Razafsky, Bhubanananda Sahu, Susan Q. Shen, Chloe Potter, Lisa L. Sandell, Joseph C. Corbo, Krzysztof Palczewski, Akiko Maeda, Didier Hodzic, Vladimir J. Kefalov
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Pigment regeneration is critical for the function of cone photoreceptors in bright and rapidly-changing light conditions. This process is facilitated by the recently-characterized retina visual cycle, in which Müller cells recycle spent all
Externí odkaz:
https://doaj.org/article/392513b8e5794336a8525df1ce0d8453
Autor:
David Razafsky, Didier Hodzic
Publikováno v:
Neurobiology of Disease, Vol 78, Iss , Pp 57-67 (2015)
Nonsense mutations across the whole coding sequence of Syne1/Nesprin1 have been linked to autosomal recessive cerebellar ataxia Type I (ARCA1). However, nothing is known about the molecular etiology of this late-onset debilitating pathology. In this
Externí odkaz:
https://doaj.org/article/65d95b09955349e586cc88161803faac
Publikováno v:
FASEB J
The nuclei of cone photoreceptors are located on the apical side of the outer nuclear layer (ONL) in vertebrate retinas. However, the functional role of this evolutionarily conserved localization of cone nuclei is unknown. We previously showed that L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f26a392d2cd2f409e2459302c8c53f
https://europepmc.org/articles/PMC7688549/
https://europepmc.org/articles/PMC7688549/
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47180 (2012)
It has long been observed that many neuronal types position their nuclei within restricted cytoplasmic boundaries. A striking example is the apical localization of cone photoreceptors nuclei at the outer edge of the outer nuclear layer of mammalian r
Externí odkaz:
https://doaj.org/article/3bcd6627209549b89c544f9ba305932f
Publikováno v:
genesis. 54:129-135
The developing mouse retina is a tractable model for studying neurogenesis and differentiation. Although transgenic Cre mouse lines exist to mediate conditional genetic manipulations in developing mouse retinas, none of them act specifically in early
Autor:
Audrey Chang, Katherine Achtien, Colette Cote, Lakshmi Viswanathan, Yitao Tang, David Razafsky, Trissa Borgschulte, Alexei I. Slesarev, David Onions
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
The robust detection of structural variants in mammalian genomes remains a challenge. It is particularly difficult in the case of genetically unstable Chinese hamster ovary (CHO) cell lines with only draft genome assemblies available. We explore the
Autor:
Xia Ge, Moe R. Mahjoub, Chloe Potter, David Razafsky, David F. Wozniak, Didier Hodzic, M. Casey, S. Penrose
Publikováno v:
Neurobiology of Disease, Vol 115, Iss, Pp 82-91 (2018)
Biallelic nonsense mutations of SYNE1 underlie a variable array of cerebellar and non-cerebellar pathologies of unknown molecular etiology. SYNE1 encodes multiple isoforms of Nesprin1 that associate with the nuclear envelope, with large cerebellar sy
Autor:
David Razafsky, Joseph C. Corbo, Krzysztof Palczewski, Vladimir J. Kefalov, Lisa L. Sandell, Yunlu Xue, Shinya Sato, Bhubanananda Sahu, Akiko Maeda, Susan Q. Shen, Didier Hodzic, Chloe Potter
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific reports, vol 7, iss 1
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific reports, vol 7, iss 1
Pigment regeneration is critical for the function of cone photoreceptors in bright and rapidly-changing light conditions. This process is facilitated by the recently-characterized retina visual cycle, in which Müller cells recycle spent all-trans-re