Výsledky vyhledávání - "David, Ranganathan"

Safety of PSMA-Targeted Molecular Radioligand Therapy with 177Lu-PSMA-617: Results from the Prospective Multicenter Phase 2 Trial RESIST-PC (NCT03042312)

Autor: Wolfgang P. Fendler, Shadfar Bahri, David Ranganathan, Jeannine Gartmann, Johannes Czernin, Jeremie Calais, Rouzbeh Esfandiari, Martin Allen-Auerbach, Pan Thin, Beilei He, Kathleen Nguyen, Linda Gardner, Wesley R Armstrong, Andrew Quon, Pawan Gupta, Ken Herrmann, Magnus Dahlbom, Ebrahim S. Delpassand, Matthias Eiber

Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine, vol 62, iss 10

The purpose of this analysis was to report the safety evaluation of 177Lu-PSMA-617 derived from the cohort of 64 patients exposed to 177Lu-PSMA-617 in the RESIST-PC trial NCT03042312. Methods: RESIST-PC was a prospective multicenter phase 2 trial. Pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f93c9519090ec3e7cb8a41201dd19de
https://escholarship.org/uc/item/3n3680n9

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64Cu-DOTATATE PET/CT for Imaging Patients with Known or Suspected Somatostatin Receptor–Positive Neuroendocrine Tumors: Results of the First U.S. Prospective, Reader-Masked Clinical Trial

Autor: Ayman M. Gaber, Rodolfo Nunez, Andreas Kjaer, Afshin Shafie, David Ranganathan, Ali Abbasi, Nilesh K. Wagh, Ebrahim S. Delpassand, Izabela Tworowska

Publikováno v: Journal of Nuclear Medicine. 61:890-896

Studies demonstrate that the investigational 64Cu-DOTATATE radiopharmaceutical may provide diagnostic and logistical benefits over available imaging agents for patients with somatostatin receptor (SSTR)–positive neuroendocrine tumors (NETs). Accord

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b587d7f504b18994a9b4ea13dd1c8f94
https://doi.org/10.2967/jnumed.119.236091

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Safety of PSMA-Targeted Molecular Radioligand Therapy with

Autor: Jeremie, Calais, Johannes, Czernin, Pan, Thin, Jeannine, Gartmann, Kathleen, Nguyen, Wesley R, Armstrong, Martin, Allen-Auerbach, Andrew, Quon, Shadfar, Bahri, Pawan, Gupta, Linda, Gardner, Magnus, Dahlbom, Beilei, He, Rouzbeh, Esfandiari, David, Ranganathan, Ken, Herrmann, Matthias, Eiber, Wolfgang P, Fendler, Ebrahim, Delpassand

Publikováno v: J Nucl Med

The purpose of this analysis was to report the safety evaluation of (177)Lu-PSMA-617 derived from the cohort of 64 patients exposed to (177)Lu-PSMA-617 in the RESIST-PC trial NCT03042312. Methods: RESIST-PC was a prospective multicenter phase 2 trial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::da29e7b8ea8c11e92000fb2d99262636
https://pubmed.ncbi.nlm.nih.gov/34272322

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Prospective phase 2 trial of PSMA-targeted molecular RadiothErapy with

Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine, vol 62, iss 10
J Nucl Med

The objective of this study was to determine prospectively the efficacy profile of 2 activity regimens of (177)Lu-PSMA therapy in patients with progressive metastatic castrate-resistant prostate cancer (mCRPC): 6.0 vs. 7.4 GBq. Methods: RESIST-PC (NC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354aa7aca16d8b533d44dfa8ed3839ad
https://pubmed.ncbi.nlm.nih.gov/34353872

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Abstract P099: Radionuclide imaging of low-density-lipoprotein receptor (LDLR)-overexpressing glioblastoma: A preclinical study of Gallium-68 RMX-VH

Autor: Izabela Tworowska, Leo Garcia Flores, Xuewei Qu, Cédric Malicet, Nilesh Wagh, David Ranganathan, Jonathan Nowak, Pascaline Lecorche, Jamal Temsamani, Ebrahim S. Delpassand

Publikováno v: Molecular Cancer Therapeutics. 20:P099-P099

Introduction: One of the factors that limit the efficacy of the drugs, especially in primary brain tumors, is the permeability of the blood-brain barrier (BBB). The low-density lipoprotein receptor (LDL-R) expressed at the BBB mediates the transport

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f570f53a1f4edd8e88ece67bcae22247
https://doi.org/10.1158/1535-7163.targ-21-p099

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Radiosynthesis of clinical doses of 68 Ga-DOTATATE (GalioMedix™) and validation of organic-matrix-based 68 Ge/ 68 Ga generators

Autor: Izabela Tworowska, Ebrahim S. Delpassand, Sanjay Thamake, Konstantin Zhernosekov, Sebastian Marx, David Ranganathan, Alireza Mojtahedi, Michael K. Schultz

Publikováno v: Nuclear Medicine and Biology. 43:19-26

Introduction 68Ga-DOTATATE is a radiolabeled peptide-based agonist that targets somatostatin receptors overexpressed in neuroendocrine tumors. Here, we present our results on validation of organic matrix 68Ge/68Ga generators (ITG GmbH) applied for ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::149594cf55edae9221c32387173a198f
https://doi.org/10.1016/j.nucmedbio.2015.08.004

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Peptide Receptor Radionuclide Therapy With 177Lu-Octreotate in Patients With Somatostatin Receptor Expressing Neuroendocrine Tumors: Six Years' Assessment

Autor: Edward M. Wolin, Thomas M. O'Dorisio, Muzammil Ali, David Ranganathan, Izabela Tworowska, Ebrahim S. Delpassand, Mohammadali Hamiditabar, Joseph Roys, Jonathan R. Strosberg

Publikováno v: Clin Nucl Med

Peptide receptor radionuclide therapy (PRRT) with radiolabeled somatostatin analogues is a promising treatment for patients with inoperable, well to moderately differentiated metastatic neuroendocrine tumors (NETs). In continuation of our novel study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::730a17126c66f543a0a947670d4e5635
https://pubmed.ncbi.nlm.nih.gov/28263217

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Long-term evaluation of TiO2-based 68Ge/68Ga generators and optimized automation of [68Ga]DOTATOC radiosynthesis

Autor: Aviv Hagooly, Tetsuya Mori, Suzanne E. Lapi, David Ranganathan, Mai Lin, Michael J. Welch, Raffaella Rossin

Publikováno v: Applied Radiation and Isotopes. 70:2539-2544

Interest in using 68 Ga is rapidly increasing for clinical PET applications due to its favorable imaging characteristics and increased accessibility. The focus of this study was to provide our long-term evaluations of the two TiO 2 -based 68 Ge/ 68 G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::944f841682578de0bcee44fb35190fdd
https://doi.org/10.1016/j.apradiso.2012.05.009

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Electrochemical synthesis of nano-cobalt hexacyanoferrate at a sol–gel-coated electrode templated with β-cyclodextrin

Autor: David Ranganathan, James A. Cox, Paolo Conti, Silvia Zamponi, Marco Giorgetti, Mario Berrettoni

Publikováno v: Journal of Solid State Electrochemistry. 16:2861-2866

The paper describes the time-dependent evolution of the electrochemical deposition of cobalt hexacyanoferrate (CoHCFe) on graphite foil electrode modified with electrochemically formed sol–gel film doped with β-cyclodextrin to impart porosity. Wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::903e33443ccbe9731cfbb78273be6fca
https://doi.org/10.1007/s10008-012-1714-7

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