Zobrazeno 1 - 10
of 29
pro vyhledávání: '"David, Pleasure"'
Autor:
Vanessa L. Hull, Yan Wang, Jennifer McDonough, Meina Zhu, Travis Burns, Najmah Al Ramel, Ali Dehghani, Fuzheng Guo, David Pleasure
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 4, Pp 1059-1062 (2024)
Abstract Canavan disease is a leukodystrophy caused by ASPA mutations that diminish oligodendroglial aspartoacylase activity, and is characterized by markedly elevated brain concentrations of the aspartoacylase substrate N‐acetyl‐l‐aspartate (N
Externí odkaz:
https://doaj.org/article/eeb55501af2040ab83c03837d9466fbf
Publikováno v:
Advanced Science, Vol 9, Iss 5, Pp n/a-n/a (2022)
Abstract Poly (ADP‐ribose) polymerase 1 (PARP1) plays a fundamental role in DNA repair and gene expression. Excessive PARP1 hyperactivation, however, has been associated with cell death. PARP1 and/or its activity are dysregulated in the immune and
Externí odkaz:
https://doaj.org/article/6c76caf8d7394ec384e23e020dec9400
Autor:
Florian Mayrhofer, Zhanna Dariychuk, Anthony Zhen, Daniel J. Daugherty, Peter Bannerman, Angela M. Hanson, David Pleasure, Athena Soulika, Wenbin Deng, Olga V. Chechneva
Publikováno v:
Neurobiology of Disease, Vol 161, Iss , Pp 105556- (2021)
Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease with high variability of clinical symptoms. In most cases MS appears as a relapsing-remitting disease course that at a later stage transitions into irreversible progressive decline
Externí odkaz:
https://doaj.org/article/302d5ae29ee14ef795820b683ac8af09
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204536 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0167573.].
Externí odkaz:
https://doaj.org/article/a0f28c54c2944e759631a31fd0f5c776
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167573 (2016)
Charcot-Marie-Tooth disease type 2A (CMT2A), the most common axonal form of hereditary sensory motor neuropathy, is caused by mutations of mitofusin-2 (MFN2). Mitofusin-2 is a GTPase required for fusion of mitochondrial outer membranes, repair of dam
Externí odkaz:
https://doaj.org/article/164a7964088747d0b17872301df0558a
Publikováno v:
Neurobiology of Disease, Vol 43, Iss 2, Pp 473-485 (2011)
Preconditioning-induced ischemic tolerance has been documented in the newborn brain, however, the signaling mechanisms of this preconditioning require further elucidation. The aims of this study were to develop a hypoxic-preconditioning (PC) model of
Externí odkaz:
https://doaj.org/article/cdf855661a9f45f9866af9127e3b429d
Autor:
Sean Ekins, Nadia K. Litterman, Renée J.G. Arnold, Robert W. Burgess, Joel S. Freundlich, Steven J. Gray, Joseph J. Higgins, Brett Langley, Dianna E. Willis, Lucia Notterpek, David Pleasure, Michael W. Sereda, Allison Moore
Publikováno v:
F1000Research, Vol 4 (2015)
This brief review of current research progress on Charcot-Marie-Tooth (CMT) disease is a summary of discussions initiated at the Hereditary Neuropathy Foundation (HNF) scientific advisory board meeting on November 7, 2014. It covers recent published
Externí odkaz:
https://doaj.org/article/3547c770fb444cc882536cb3aeb4f6a8
Publikováno v:
Neurobiology of Disease, Vol 11, Iss 1, Pp 199-213 (2002)
Acid sphingomyelinase (ASMase) and NF-κB participate in tumor necrosis factor α (TNFα) signal transduction. Mice in which the genes encoding ASMase or the p50 subunit of NF-κB are disrupted have been reported to be less vulnerable than wild-type
Externí odkaz:
https://doaj.org/article/2f6ede74064f466f849ab9db1ab61c02
Autor:
Florian, Mayrhofer, Zhanna, Dariychuk, Anthony, Zhen, Daniel J, Daugherty, Peter, Bannerman, Angela M, Hanson, David, Pleasure, Athena, Soulika, Wenbin, Deng, Olga V, Chechneva
Publikováno v:
Neurobiology of disease. 161
Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease with high variability of clinical symptoms. In most cases MS appears as a relapsing-remitting disease course that at a later stage transitions into irreversible progressive decline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a94650319e747d98554c443f5b56bc73
https://pubmed.ncbi.nlm.nih.gov/34752925
https://pubmed.ncbi.nlm.nih.gov/34752925
Autor:
Jiho Sohn, Peter Bannerman, Fuzheng Guo, Travis Burns, Laird Miers, Christopher Croteau, Naveen K. Singhal, Jennifer A. McDonough, David Pleasure
Publikováno v:
The Journal of Neuroscience. 37:413-421
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9f5d5749aa5b1044c2a65bccb5f984b
https://doi.org/10.1523/jneurosci.2013-16.2017
https://doi.org/10.1523/jneurosci.2013-16.2017