Zobrazeno 1 - 10
of 79
pro vyhledávání: '"David, Meiri"'
Publikováno v:
Talanta Open, Vol 10, Iss , Pp 100358- (2024)
The Cannabis plant contains many groups of bioactive metabolites with potential pharmacological properties. These properties have mainly been attributed to cannabinoids and terpenoids, with other groups receiving little attention. The usefulness of t
Externí odkaz:
https://doaj.org/article/b9ab2e61f6bb4258bc2583ed8808a26f
Publikováno v:
eLife, Vol 12 (2024)
In T-cell acute lymphoblastic leukemia (T-ALL), more than 50% of cases display autoactivation of Notch1 signaling, leading to oncogenic transformation. We have previously identified a specific chemovar of Cannabis that induces apoptosis by preventing
Externí odkaz:
https://doaj.org/article/992a7a0a20fe47ebbdecbe6108e0dd96
Autor:
Joshua M. Hazan, Raziel Amador, Tahleel Ali-Nasser, Tamar Lahav, Stav Roni Shotan, Miryam Steinberg, Ziv Cohen, Dvir Aran, David Meiri, Yehuda G. Assaraf, Roderic Guigó, Assaf C. Bester
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-19 (2024)
Abstract Background Long non-coding RNAs (lncRNAs) are pivotal players in cellular processes, and their unique cell-type specific expression patterns render them attractive biomarkers and therapeutic targets. Yet, the functional roles of most lncRNAs
Externí odkaz:
https://doaj.org/article/0a7a3f91e9a74ebfbf0006c5add69662
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Since adult stem cells are responsible for replenishing tissues throughout life, it is vital to understand how failure to undergo apoptosis can dictate stem cell behavior both intrinsically and non-autonomously. Here, we report that depletio
Externí odkaz:
https://doaj.org/article/c051d054abb647e790758fb8ec3934dd
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Seaweeds of the intertidal zone are subjected to diverse stresses due to environmental changes in radiation, salinity, water quality, herbivore communities, etc. Thus, marine seaweeds developed various unique compounds to deal with environme
Externí odkaz:
https://doaj.org/article/1cc5099c7be74807a8b9fe73597db67f
Autor:
Shiraz Vered, Alexa S. Beiser, Liron Sulimani, Sharon Sznitman, Mitzi M. Gonzales, Hugo J. Aparicio, Charles DeCarli, Matthew R. Scott, Saptaparni Ghosh, Gil M. Lewitus, David Meiri, Sudha Seshadri, Galit Weinstein
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Background Preclinical studies highlight the importance of endogenous cannabinoids (endocannabinoids; eCBs) in neurodegeneration. Yet, prior observational studies focused on limited outcome measures and assessed only few eCB compounds while
Externí odkaz:
https://doaj.org/article/093f68cbea874b4aa79ffe745a7b724d
Autor:
Elazar Besser, Anat Gelfand, Gil Moshe Lewitus, Hila Novak‐Kotzer, Shiri Procaccia, Paula Berman, Igal Louria‐Hayon, Inbar Shreiber‐Livne, Yishai Ofran, David Meiri
Publikováno v:
Cancer Communications, Vol 43, Iss 6, Pp 711-715 (2023)
Externí odkaz:
https://doaj.org/article/1a3ff57b52e44333a85c3b92ab490c20
Autor:
Iris Wyrobnik, Miryam Steinberg, Anat Gelfand, Ronen Rosenblum, Yara Eid Mutlak, Liron Sulimani, Shiri Procaccia, Yishai Ofran, Hila Novak-Kotzer, David Meiri
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTDuring solid tumor progression, the tumor microenvironment (TME) evolves into a highly immunosuppressive milieu. Key players in the immunosuppressive environment are regulatory myeloid cells, including myeloid-derived suppressor cells (MDSCs)
Externí odkaz:
https://doaj.org/article/39ec33dd04e2407db267ecc7cf92338a
Autor:
Joshua Aviram, Marek Glezerman, Eytan Hayam, Rostislav Belobrov, Shiri Procaccia, David Meiri, Elon Eisenberg
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1426 (2023)
Background: Clinical studies on medical cannabis (MC) treatment have shown sex-related differences, including higher susceptibility to adverse events among women and greater analgesia among men. Here, we used the Syqe metered-dose inhaler (MDI) and a
Externí odkaz:
https://doaj.org/article/dfa96d2a344e4ccca049346ebb72fca0
Autor:
Orit Stolar, Ariela Hazan, Roni Enten Vissoker, Ibrahim Abu Kishk, Dana Barchel, Mirit Lezinger, Adi Dagan, Nir Treves, David Meiri, Matitiahu Berkovitch, Elkana Kohn, Eli Heyman
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Autistic Spectrum Disorder (ASD) is a common neurodevelopmental disorder and no effective treatment for the core symptoms is currently available. The present study is part of a larger clinical trial assessing the effects of cannabis oil o
Externí odkaz:
https://doaj.org/article/b5bbee4f57f649bfac7dd18015676bda