Zobrazeno 1 - 10
of 30
pro vyhledávání: '"David, Linch"'
Autor:
Christos Panayi, Ayse U. Akarca, Alan D. Ramsay, Ananth G. Shankar, Brunangelo Falini, Miguel A. Piris, David Linch, Teresa Marafioti
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThe clinicopathological spectrum of nodular lymphocyte predominant Hodgkin lymphoma (NLPHL), also known as nodular lymphocyte predominant B-cell lymphoma, partially overlaps with T-cell/histiocyte-rich large B-cell lymphoma (THRLCBL). NLPHL
Externí odkaz:
https://doaj.org/article/a9583936f525471a8aa038037f2ce241
Autor:
Wei-Yu Lin, Sarah E. Fordham, Eric Hungate, Nicola J. Sunter, Claire Elstob, Yaobo Xu, Catherine Park, Anne Quante, Konstantin Strauch, Christian Gieger, Andrew Skol, Thahira Rahman, Lara Sucheston-Campbell, Junke Wang, Theresa Hahn, Alyssa I. Clay-Gilmour, Gail L. Jones, Helen J. Marr, Graham H. Jackson, Tobias Menne, Mathew Collin, Adam Ivey, Robert K. Hills, Alan K. Burnett, Nigel H. Russell, Jude Fitzgibbon, Richard A. Larson, Michelle M. Le Beau, Wendy Stock, Olaf Heidenreich, Abrar Alharbi, David J. Allsup, Richard S. Houlston, Jean Norden, Anne M. Dickinson, Elisabeth Douglas, Clare Lendrem, Ann K. Daly, Louise Palm, Kim Piechocki, Sally Jeffries, Martin Bornhäuser, Christoph Röllig, Heidi Altmann, Leo Ruhnke, Desiree Kunadt, Lisa Wagenführ, Heather J. Cordell, Rebecca Darlay, Mette K. Andersen, Maria C. Fontana, Giovanni Martinelli, Giovani Marconi, Miguel A. Sanz, José Cervera, Inés Gómez-Seguí, Thomas Cluzeau, Chimène Moreilhon, Sophie Raynaud, Heinz Sill, Maria Teresa Voso, Francesco Lo-Coco, Hervé Dombret, Meyling Cheok, Claude Preudhomme, Rosemary E. Gale, David Linch, Julia Gaal-Wesinger, Andras Masszi, Daniel Nowak, Wolf-Karsten Hofmann, Amanda Gilkes, Kimmo Porkka, Jelena D. Milosevic Feenstra, Robert Kralovics, David Grimwade, Manja Meggendorfer, Torsten Haferlach, Szilvia Krizsán, Csaba Bödör, Friedrich Stölzel, Kenan Onel, James M. Allan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Genome wide association studies in cancer are used to understand the heritable genetic contribution to disease risk. Here, the authors perform a genome wide association study in European patients with acute myeloid leukemia and identify loci associat
Externí odkaz:
https://doaj.org/article/b98174c0ab9448b282785b148dd6b082
Autor:
Richard D Neal, Amitava Banerjee, Deenan Pillay, Vahe Nafilyan, Clare Turnbull, Harry Hemingway, Bryan Williams, Mark Lawler, Monica Jones, Spiros Denaxas, Kathy Pritchard-Jones, Mahdad Noursadeghi, Richard Sullivan, Graham R Foster, Ben Humberstone, Alvina G Lai, Laura Pasea, Geoff Hall, Wai Hoong Chang, Michail Katsoulis, David Linch, Derralynn Hughes, Martin D Forster, Natalie K Fitzpatrick, Kathryn Boyd, Tariq Enver, Matt Cooper, Charlie Davie
Publikováno v:
BMJ Open, Vol 10, Iss 11 (2020)
Objectives To estimate the impact of the COVID-19 pandemic on cancer care services and overall (direct and indirect) excess deaths in people with cancer.Methods We employed near real-time weekly data on cancer care to determine the adverse effect of
Externí odkaz:
https://doaj.org/article/c2f616624f704551b06859ee195496c9
Autor:
Wei-Yu Lin, Sarah E. Fordham, Eric Hungate, Nicola J. Sunter, Claire Elstob, Yaobo Xu, Catherine Park, Anne Quante, Konstantin Strauch, Christian Gieger, Andrew Skol, Thahira Rahman, Lara Sucheston-Campbell, Junke Wang, Theresa Hahn, Alyssa I. Clay-Gilmour, Gail L. Jones, Helen J. Marr, Graham H. Jackson, Tobias Menne, Mathew Collin, Adam Ivey, Robert K. Hills, Alan K. Burnett, Nigel H. Russell, Jude Fitzgibbon, Richard A. Larson, Michelle M. Le Beau, Wendy Stock, Olaf Heidenreich, Abrar Alharbi, David J. Allsup, Richard S. Houlston, Jean Norden, Anne M. Dickinson, Elisabeth Douglas, Clare Lendrem, Ann K. Daly, Louise Palm, Kim Piechocki, Sally Jeffries, Martin Bornhäuser, Christoph Röllig, Heidi Altmann, Leo Ruhnke, Desiree Kunadt, Lisa Wagenführ, Heather J. Cordell, Rebecca Darlay, Mette K. Andersen, Maria C. Fontana, Giovanni Martinelli, Giovanni Marconi, Miguel A. Sanz, José Cervera, Inés Gómez-Seguí, Thomas Cluzeau, Chimène Moreilhon, Sophie Raynaud, Heinz Sill, Maria Teresa Voso, Francesco Lo-Coco, Hervé Dombret, Meyling Cheok, Claude Preudhomme, Rosemary E. Gale, David Linch, Julia Gaal-Wesinger, Andras Masszi, Daniel Nowak, Wolf-Karsten Hofmann, Amanda Gilkes, Kimmo Porkka, Jelena D. Milosevic Feenstra, Robert Kralovics, David Grimwade, Manja Meggendorfer, Torsten Haferlach, Szilvia Krizsán, Csaba Bödör, Friedrich Stölzel, Kenan Onel, James M. Allan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/1723b41ffb3e40a6be29fdc671afedd7
Autor:
Claire Roddie, Lazaros J. Lekakis, Maria A. V. Marzolini, Aravind Ramakrishnan, Yiyun Zhang, Yanqing Hu, Vijay G R Peddareddigari, Nushmia Z Khokhar, Robert W Chen, Silvia Basilico, Meera Raymond, Frederick Arce Vargas, Kevin Duffy, Wolfram Brugger, Maeve O'Reilly, Leigh Wood, David Linch, Karl S Peggs, Carlos Bachier, Elizabeth Lihua Budde, Connie Lee Batlevi, Nancy L. Bartlett, David Irvine, Eleni Tholouli, Wendy Osborne, Kirit M Ardeshna, Martin Pule
Publikováno v:
Blood.
Relapse following CD19-directed chimeric antigen receptor T-cells (CAR-T) for relapsed/refractory large B-cell lymphoma (r/r LBCL) is commonly ascribed to antigen loss or CAR-T exhaustion. Multi-antigen targeting and PD-1 blockade are rational approa
Autor:
Yeman B. Hagos, Ayse U. Akarca, Alan Ramsay, Riccardo L. Rossi, Sabine Pomplun, Victoria Ngai, Alessia Moioli, Andrea Gianatti, Christopher Mcnamara, Alessandro Rambaldi, Sergio A. Quezada, David Linch, Giuseppe Gritti, Yinyin Yuan, Teresa Marafioti
Publikováno v:
Hematological Oncology. 40:541-553
The spatial architecture of the lymphoid tissue in follicular lymphoma (FL) presents unique challenges to studying its immune microenvironment. We investigated the spatial interplay of T cells, macrophages, myeloid cells and natural killer T cells us
Autor:
Claire Roddie, Juliana Dias, Maeve O’Reilly, Marina Mitsikakou, Eftychia Charalambous, Louisa Green, Mhairi Vaughn, Giulia Agliardi, John Garcia, Evie Lewin, Mark Lowdell, Maria Marzolini, Helen Holmes, Yenting Ngai, Bilyana Popova, William Wilson, Sangeetha Kunaseelan, Victoria Spanswick, Helen Lowe, Leah Ensell, John Hartley, David Linch, Adrian J Bloor, David Irvine, Martin Pule, Karl S. Peggs
Publikováno v:
Transplantation and Cellular Therapy. 29:S213-S214
Autor:
Rahul Raj Aggarwal, Jingsong Zhang, Xinhua Zhu, Paul Monk, Robert J. Jones, Mark David Linch, Dan Costin, Johann S. De Bono, Lawrence Ivan Karsh, Daniel P. Petrylak, Pascal Borderies, Rashmi Majali Deshpande, Amir Hafeez, Vincent J. O'Neill, Scott T. Tagawa
Publikováno v:
Journal of Clinical Oncology. 41:176-176
176 Background: BXCL701 (talabostat), oral small molecule inhibitor of dipeptidyl peptidases (DPP)—primarily DPP8/9 & DPP4—triggers inflammasome to alert and prime immune cells, leading to induction of IL-18 & IL-1ß, bridging innate & adaptive i
Autor:
Michael J. Morris, Mark David Linch, Simon J. Crabb, Tomasz M. Beer, Elisabeth I. Heath, Michael S. Gordon, Johann S. De Bono, Hristina I Pashova, Iulia Cristina Tudor, Andrew E Greenstein, Grace Mann, Glenn Liu
Publikováno v:
Journal of Clinical Oncology. 41:145-145
145 Background: Metastatic castration-resistant prostate cancer (mCRPC) remains an incurable disease with significant morbidity. Androgen receptor (AR) signaling is a key driver of tumor growth in mCRPC, and AR-targeted therapies are the mainstay for
Autor:
Simon Rule, Paul Smith, Peter W.M. Johnson, Simon Bolam, George Follows, Joanne Gambell, Peter Hillmen, Andrew Jack, Stephen Johnson, Amy A Kirkwood, Anton Kruger, Christopher Pocock, John F. Seymour, Milena Toncheva, Jan Walewski, David Linch
Publikováno v:
Haematologica, Vol 101, Iss 2 (2016)
Mantle cell lymphoma is an incurable and generally aggressive lymphoma that is more common in elderly patients. Whilst a number of different chemotherapeutic regimens are active in this disease, there is no established gold standard therapy. Rituxima
Externí odkaz:
https://doaj.org/article/f337005569d54ae79221956560b278ff