Zobrazeno 1 - 10
of 18
pro vyhledávání: '"David, Kunkel"'
Autor:
Thomas Payne, Jennifer Taylor, David Kunkel, Katherine Konieczka, Frankie Ingram, Kaj Blennow, Henrik Zetterberg, Robert A. Pearce, Anke Meyer-Franke, Niccolò Terrando, Katerina Akassoglou, Robert D. Sanders, Richard C. Lennertz
Publikováno v:
BJA Open, Vol 12, Iss , Pp 100349- (2024)
Background: We aimed to assess perioperative changes in fibrinogen in the cerebrospinal fluid (CSF), their association with markers of blood–brain barrier breakdown and neuroinflammation, and their association with postoperative delirium severity.
Externí odkaz:
https://doaj.org/article/46f97a63a6754a3c850420900105059e
Autor:
David Kunkel, Margaret Parker, Cameron Casey, Bryan Krause, Jennifer Taylor, Robert A. Pearce, Richard Lennertz, Robert D. Sanders
Publikováno v:
BJA Open, Vol 2, Iss , Pp 100006- (2022)
Background: Perioperative inflammation is associated with perioperative complications, including delirium, that are associated with a reduced number of postoperative days alive and at home at 90 days (DAH90). We tested whether inflammation was associ
Externí odkaz:
https://doaj.org/article/49c4e74195864577ae5b73a79117fc6d
Autor:
Thomas Payne, Jennifer Taylor, Cameron Casey, David Kunkel, Maggie Parker, Kaj Blennow, Henrik Zetterberg, Robert A. Pearce, Richard C. Lennertz, Robert D. Sanders
Publikováno v:
British Journal of Anaesthesia. 130:546-556
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e380562929a000320a7eadc19ab43b9
https://doi.org/10.1016/j.bja.2023.01.020
https://doi.org/10.1016/j.bja.2023.01.020
Autor:
Jennifer Taylor, Laura Eisenmenger, Heidi Lindroth, James Booth, Rosaleena Mohanty, Veena Nair, Margaret Parker, David Kunkel, Cameron Rivera, Cameron Casey, Henrik Zetterberg, Kaj Blennow, Marko Mrkobrada, Philip J. Devereaux, Robert A. Pearce, Richard Lennertz, Vivek Prabhakaran, Robert D. Sanders
Publikováno v:
British Journal of Anaesthesia. 130:e361-e369
Ischaemic brain infarction can occur without acute neurological symptoms (covert strokes) or with symptoms (overt strokes), both associated with poor health outcomes. We conducted a pilot study of the incidence of preoperative and postoperative (intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07fc9c3262012bca46189b57393731dd
https://doi.org/10.1016/j.bja.2022.10.018
https://doi.org/10.1016/j.bja.2022.10.018
Publikováno v:
British Journal of Anaesthesia. 130:e449-e451
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d2075160811a2248397c8e7a788a4de
https://doi.org/10.1016/j.bja.2023.02.002
https://doi.org/10.1016/j.bja.2023.02.002
Autor:
Jennifer Taylor, Margaret Parker, Cameron P. Casey, Sean Tanabe, David Kunkel, Cameron Rivera, Henrik Zetterberg, Kaj Blennow, Robert A. Pearce, Richard C. Lennertz, Robert D. Sanders
Publikováno v:
British Journal of Anaesthesia. 129:219-230
Case-control studies have associated delirium with blood-brain barrier (BBB) permeability. However, this approach cannot determine whether delirium is attributable to high pre-existing permeability or to perioperative changes. We tested whether perio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33fe8142a629edf13157ce6cfbec9d9f
https://doi.org/10.1016/j.bja.2022.01.005
https://doi.org/10.1016/j.bja.2022.01.005
Autor:
Justin G. Wu, Jennifer Taylor, Maggie Parker, David Kunkel, Cameron Rivera, Robert A. Pearce, Richard Lennertz, Robert D. Sanders
Publikováno v:
Br J Anaesth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d2812721e9c4acd84fb3b553f20528c
https://doi.org/10.1016/j.bja.2021.12.037
https://doi.org/10.1016/j.bja.2021.12.037
Autor:
Jennifer Taylor, Thomas Payne, Cameron Casey, David Kunkel, Maggie Parker, Cameron Rivera, Henrik Zetterberg, Kaj Blennow, Robert A. Pearce, Richard C. Lennertz, Tim McCulloch, Amy Gaskell, Robert D. Sanders
Publikováno v:
British journal of anaesthesia.
Recent trials are conflicting as to whether titration of anaesthetic dose using electroencephalography monitoring reduces postoperative delirium. Titration to anaesthetic dose itself might yield clearer conclusions. We analysed our observational coho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5304d3ec555852f3cf59891b9d171726
https://pubmed.ncbi.nlm.nih.gov/36192219
https://pubmed.ncbi.nlm.nih.gov/36192219
Autor:
David Kunkel, Marissa White, Benjamin Schessler, Richard Lennertz, Lenka Craigova, Robert A. Pearce, Cameron Casey, Margaret Parker, Henrik Zetterberg, Robert D. Sanders, Kaj Blennow
Publikováno v:
Br J Anaesth
BACKGROUND: Myocardial and neuronal injury occur commonly after noncardiac surgery. We examined whether patients who had perioperative myocardial injury (PMI) also incurred neuronal injury, and whether myocardial and neuronal injury were associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c82f0f6a357a96ef2527f20e4708c89
https://doi.org/10.1016/j.bja.2020.10.012
https://doi.org/10.1016/j.bja.2020.10.012
Autor:
Klevest Gjini, Cameron Casey, Sean Tanabe, Amber Bo, Margaret Parker, Marissa White, David Kunkel, Richard Lennertz, Robert A Pearce, Tobey Betthauser, Bradley T Christian, Sterling C Johnson, Barbara B Bendlin, Robert D Sanders
Publikováno v:
Brain communications. 4(5)
Altered predictive coding may underlie the reduced auditory mismatch negativity amplitude observed in patients with dementia. We hypothesized that accumulating dementia-associated pathologies, including amyloid and tau, lead to disturbed predictions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703d8199866eb47d4e8803ee0755083f
https://pubmed.ncbi.nlm.nih.gov/36226138
https://pubmed.ncbi.nlm.nih.gov/36226138