Zobrazeno 1 - 10
of 71
pro vyhledávání: '"David, Križaj"'
Autor:
Brenan Cullimore, Jackson Baumann, Christopher N Rudzitis, Andrew O Jo, Denisa Kirdajova, David Križaj
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 5, Pp 1031-1032 (2023)
Externí odkaz:
https://doaj.org/article/0353d7fb69d64c3f89e493b69b5f8bf7
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/be4f868448c14fbcb0e0ce53e4994c88
Autor:
Oleg Yarishkin, Tam T. T. Phuong, Felix Vazquez-Chona, Jacques Bertrand, Joseph van Battenburg-Sherwood, Sarah N. Redmon, Christopher N. Rudzitis, Monika Lakk, Jackson M. Baumann, Marc Freichel, Eun-Mi Hwang, Darryl Overby, David Križaj
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Trabecular meshwork (TM) cells are phagocytic cells that employ mechanotransduction to actively regulate intraocular pressure. Similar to macrophages, they express scavenger receptors and participate in antigen presentation within the immunosuppressi
Externí odkaz:
https://doaj.org/article/e878d86628904c698824107f4feebaa7
Autor:
Monika Lakk, Grace F. Hoffmann, Aruna Gorusupudi, Eric Enyong, Amy Lin, Paul S. Bernstein, Trine Toft-Bertelsen, Nanna MacAulay, Michael H. Elliott, David Križaj
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100145- (2021)
Despite the association of cholesterol with debilitating pressure-related diseases such as glaucoma, heart disease, and diabetes, its role in mechanotransduction is not well understood. We investigated the relationship between mechanical strain, free
Externí odkaz:
https://doaj.org/article/ddf84964e0c34f4f9e32ca66ec7cc420
Publikováno v:
Neural Regeneration Research, Vol 13, Iss 2, Pp 207-210 (2018)
Unesterified cholesterol controls the fluidity, permeability and electrical properties of eukaryotic cell membranes. Consequently, cholesterol levels in the retina and the brain are tightly regulated whereas depletion or oversupply caused by diet or
Externí odkaz:
https://doaj.org/article/6c7c4897195d49cb94d7f177465285d4
Autor:
Anna Stavniichuk, Kyrylo Pyrshev, Oleg Zaika, Viktor N. Tomilin, Mariya Kordysh, Monika Lakk, David Križaj, Oleh Pochynyuk
Publikováno v:
American Journal of Physiology-Renal Physiology.
Ca2+-permeable TRPV4 channel serves as the sensor of tubular flow thus being well-suited to govern mechanosensitive K+ transport in the distal renal tubule. Here, we directly tested whether TRPV4 function is significant in affecting K+ balance. We em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cc545cc91abf9119cc6eb4d4128621b
https://doi.org/10.1152/ajprenal.00278.2022
https://doi.org/10.1152/ajprenal.00278.2022
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Retinal ganglion cells (RGCs) are projection neurons that transmit the visual signal from the retina to the brain. Their excitability and survival can be strongly influenced by mechanical stressors, temperature, lipid metabolites, and inflammatory me
Externí odkaz:
https://doaj.org/article/ae490e8af6334ab39a8f3ed49deb741c
Autor:
Monika Lakk, Daniel R. Scoles, David Križaj, Karla P. Figueroa, Chad A Sundberg, Sharan Paul, Stefan M. Pulst
Publikováno v:
J Comp Neurol
Polyglutamine repeat expansions in the Ataxin-2 (ATXN2) gene were first implicated in Spinocerebellar Ataxia Type 2, a disease associated with degeneration of motor neurons and Purkinje cells. Recent studies linked single nucleotide polymorphisms in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5187488b0c8d2f42fe6993f19657d3d0
https://doi.org/10.1002/cne.25228
https://doi.org/10.1002/cne.25228
Publikováno v:
Cells, Vol 3, Iss 3, Pp 914-938 (2014)
Transient Receptor Potential Vanilloid 1 (TRPV1) subunits form a polymodal cation channel responsive to capsaicin, heat, acidity and endogenous metabolites of polyunsaturated fatty acids. While originally reported to serve as a pain and heat detector
Externí odkaz:
https://doaj.org/article/71ce29f831014c12bed24f09b0bf626f
Autor:
Monika Lakk, Tam T. T. Phuong, David Križaj, Michael L. De Ieso, W. Daniel Stamer, Chad A Sundberg, Jackson M Baumann, Oleg Yarishkin, Félix R. Vázquez-Chona, Christopher N. Rudzitis
Publikováno v:
J Physiol
Key points Trabecular meshwork (TM) is a highly mechanosensitive tissue in the eye that regulates intraocular pressure through the control of aqueous humour drainage. Its dysfunction underlies the progression of glaucoma but neither the mechanisms th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7fdd7c2cf14829075f73d19c8663f0
https://doi.org/10.1113/jp281011
https://doi.org/10.1113/jp281011