Zobrazeno 1 - 10
of 74
pro vyhledávání: '"David, Kobiler"'
Autor:
Itai Glinert, Elad Bar-David, Amir Ben-Shmuel, Assa Sittner, Reut Puni, Shira Laredo, David Kobiler, Shay Weiss, Haim Levy
Publikováno v:
PLoS ONE, Vol 18, Iss 2 (2023)
Bacillus anthracis overcomes host immune responses by producing capsule and secreting toxins. Production of these virulence factors in response to entering the host environment was shown to be regulated by atxA, the major virulence regulator, known t
Externí odkaz:
https://doaj.org/article/d3dbd8eaf44049c39ae0a47d334aecd5
Autor:
Assa Sittner, Amir Ben-Shmuel, Itai Glinert, Elad Bar-David, Josef Schlomovitz, David Kobiler, Shay Weiss, Haim Levy
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228917 (2020)
As Bacillus anthracis spores pose a proven bio-terror risk, the treatment focus has shifted from exposed populations to anthrax patients and the need for effective antibiotic treatment protocols increases. The CDC recommends carbapenems and Linezolid
Externí odkaz:
https://doaj.org/article/c1cb41eeaf8d4463ad522325c9628569
Autor:
Assa Sittner, Elad Bar-David, Itai Glinert, Amir Ben-Shmuel, Shay Weiss, Josef Schlomovitz, David Kobiler, Haim Levy
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186613 (2017)
Hemorrhagic meningitis is considered a complication of anthrax and was reported in about 50% of deadly cases in humans and non-human primates (NHP). Recently we demonstrated in Guinea pigs and rabbits that 100% of the B. anthracis-infected animals pr
Externí odkaz:
https://doaj.org/article/2532610b89de48649628194738593a25
Autor:
Itai Glinert, Elad Bar-David, Amir Ben-Shmuel, Assa Sittner, Reut Puni, Shira Laredo, David Kobiler, Shay Weiss, Haim Levy
Bacillus anthracis overcomes host immune responses by producing capsule and secreting toxins. Production of these virulence factors in response to entering the host environment was shown to be regulated by atxA, the major virulence regulator, known t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac2d9f2369148b8ae82ff8b6fe2beafe
https://doi.org/10.1101/2022.02.21.481328
https://doi.org/10.1101/2022.02.21.481328
Autor:
Itai Glinert, Shay Weiss, Assa Sittner, Elad Bar-David, Amir Ben-Shmuel, Josef Schlomovitz, David Kobiler, Haim Levy
Publikováno v:
Toxins, Vol 10, Iss 12, p 506 (2018)
Nonencapsulated (∆pXO2) Bacillus anthracis strains are commonly used as vaccines and for anthrax research, mainly in the mouse model. Previously, we demonstrated that the infection of rabbits, intranasally or subcutaneously, with the spores of a fu
Externí odkaz:
https://doaj.org/article/bb9889009db04113af35fc3d83d0272e
Autor:
Haim Levy, Itai Glinert, Shay Weiss, Elad Bar-David, Assa Sittner, Josef Schlomovitz, Zeev Altboum, David Kobiler
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112319 (2014)
Infection of the central nervous system is considered a complication of Anthrax and was reported in humans and non-human primates. Previously we have reported that Bacillus anthracis possesses a toxin-independent virulent trait that, like the toxins,
Externí odkaz:
https://doaj.org/article/31639f4b799a4a1eb5cc529661a23238
Autor:
Haim Levy, Itai Glinert, Shay Weiss, Assa Sittner, Josef Schlomovitz, Zeev Altboum, David Kobiler
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84947 (2014)
The accepted paradigm states that anthrax is both an invasive and toxinogenic disease and that the toxins play a major role in pathogenicity. In the guinea pig (GP) model we have previously shown that deletion of all three toxin components results in
Externí odkaz:
https://doaj.org/article/df58a90deb9f4c7eac39125882a316f8
Autor:
Haim Levy, Assa Sittner, Josef Schlomovitz, David Kobiler, Amir Ben-Shmuel, Shay Weiss, Itai Glinert, Elad Bar-David
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228917 (2020)
PLoS ONE
PLoS ONE
As Bacillus anthracis spores pose a proven bio-terror risk, the treatment focus has shifted from exposed populations to anthrax patients and the need for effective antibiotic treatment protocols increases. The CDC recommends carbapenems and Linezolid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f5cfecd9d04625fa058e65ec95bcfb5
https://doaj.org/article/c1cb41eeaf8d4463ad522325c9628569
https://doaj.org/article/c1cb41eeaf8d4463ad522325c9628569
Autor:
David Kobiler, Haim Levy, Elad Bar-David, Itai Glinert, Amir Ben-Shmuel, Assa Sittner, Shay Weiss
Publikováno v:
Defense Against Biological Attacks ISBN: 9783030030704
In nature, Anthrax is a zoonotic disease caused by the gram-positive spore-forming bacterium Bacillus anthracis usually infecting grazing animals. Taking advantage of their stability and ability to survive harsh conditions for decades, this deadly ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0b8d7b53a169d746e31fa70dd159646
https://doi.org/10.1007/978-3-030-03071-1_5
https://doi.org/10.1007/978-3-030-03071-1_5
Autor:
Zeev Altboum, Josef Schlomovitz, David Kobiler, Haim Levy, Itai Glinert, Adva Mechaly, Assa Sittner, Elad Bar-David, Shay Weiss, Amir Ben-Shmuel
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:4878-4885
Protective antigen (PA)-based vaccines are effective in preventing the development of fatal anthrax disease both in humans and in relevant animal models. The Bacillus anthracis toxins lethal toxin (lethal factor [LF] plus PA) and edema toxin (edema f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1448ef4e654772dabe10376388346695
https://doi.org/10.1128/aac.00546-16
https://doi.org/10.1128/aac.00546-16