Zobrazeno 1 - 7
of 7
pro vyhledávání: '"David, Jaciuch"'
Autor:
David Jaciuch, C. Adam Middleton, Christopher J. H. Elliott, Jack Munns, Laurence G. Wilson, Alison Fellgett, Chris Ugbode, Sangeeta Chawla
Publikováno v:
Journal of Parkinson's Disease
Background: Inherited mutations in the LRRK2 protein are common causes of Parkinson’s disease, but the mechanisms by which increased kinase activity of mutant LRRK2 leads to pathological events remain to be determined. In vitro assays (heterologous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec79169cdb25a3a75d4e99d8ab9a6077
https://doi.org/10.3233/jpd-202421
https://doi.org/10.3233/jpd-202421
Autor:
Mikko Juusola, An Dau, Zhuoyi Song, Narendra Solanki, Diana Rien, David Jaciuch, Sidhartha Anil Dongre, Florence Blanchard, Gonzalo G de Polavieja, Roger C Hardie, Jouni Takalo
Publikováno v:
eLife, Vol 6 (2017)
Small fly eyes should not see fine image details. Because flies exhibit saccadic visual behaviors and their compound eyes have relatively few ommatidia (sampling points), their photoreceptors would be expected to generate blurry and coarse retinal im
Externí odkaz:
https://doaj.org/article/723554c067f744979d9da6f89f9c889f
Autor:
Alison Fellgett, Christopher J. H. Elliott, C. Adam Middleton, Jack Munns, Sangeeta Chawla, Laurence G. Wilson, Chris Ugbode, David Jaciuch
BackgroundInherited mutations in the LRRK2 protein are the most common known cause of Parkinson’s, but the mechanisms by which increased kinase activity of mutant LRRK2 leads to pathological events remain to be determined. In vitro assays (heterolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4d4f707bce10f34e35d327d48f706b
https://eprints.whiterose.ac.uk/175533/7/jpd_2021_11_4_jpd_11_4_jpd202421_jpd_11_jpd202421.pdf
https://eprints.whiterose.ac.uk/175533/7/jpd_2021_11_4_jpd_11_4_jpd202421_jpd_11_jpd202421.pdf
Autor:
Sidhartha Dongre, Mikko Juusola, David Jaciuch, Xiaofeng Li, Diana Rien, Murali K. Bollepalli, Brian Chu, Zhuoyi Song, Lei Zheng, Roger C. Hardie, Patrick J. Dolph, Florence Blanchard, Anton Nikolaev, Ahmad N. Abou Tayoun, An Dau
Publikováno v:
The Journal of Neuroscience. 39:7132-7154
Ca2+-activated K+ channels (BK and SK) are ubiquitous in synaptic circuits, but their role in network adaptation and sensory perception remains largely unknown. Using electrophysiological and behavioral assays and biophysical modeling, we discover ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::503dbf41918ebb73eb20a4eb02b777f5
https://doi.org/10.1523/jneurosci.3213-18.2019
https://doi.org/10.1523/jneurosci.3213-18.2019
Circadian behavioural deficits, such as increased daytime naps and reduced night-time sleep, are common in Alzheimer’s disease and other tauopathies. But it has remained unclear whether these circadian abnormalities arise from tau pathology in eith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be5dab83b24a5fe04ad5dbe5e1aa6299
https://doi.org/10.1101/2020.12.14.422675
https://doi.org/10.1101/2020.12.14.422675
Autor:
Xiaofeng, Li, Ahmad, Abou Tayoun, Zhuoyi, Song, An, Dau, Diana, Rien, David, Jaciuch, Sidhartha, Dongre, Florence, Blanchard, Anton, Nikolaev, Lei, Zheng, Murali K, Bollepalli, Brian, Chu, Roger C, Hardie, Patrick J, Dolph, Mikko, Juusola
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 39(36)
Ca(2+)-activated K(+) channels (BK and SK) are ubiquitous in synaptic circuits, but their role in network adaptation and sensory perception remains largely unknown. Using electrophysiological and behavioral assays and biophysical modeling, we discove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::387f792ea26d7119e3240fba7f7c2534
https://pubmed.ncbi.nlm.nih.gov/31350259
https://pubmed.ncbi.nlm.nih.gov/31350259
Autor:
Jouni Takalo, Narendra Solanki, Sidhartha Dongre, Zhuoyi Song, Mikko Juusola, An Dau, Diana Rien, Gonzalo G. de Polavieja, Roger C. Hardie, Florence Blanchard, David Jaciuch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9143634bfb8de16b6d2404ecc48477fd
https://doi.org/10.7554/elife.26117.099
https://doi.org/10.7554/elife.26117.099