Zobrazeno 1 - 10
of 39
pro vyhledávání: '"David, Gilley"'
Publikováno v:
Cells, Vol 8, Iss 5, p 414 (2019)
Telomere dysfunction has been strongly implicated in the initiation of genomic instability and is suspected to be an early event in the carcinogenesis of human solid tumors. Recent findings have established the presence of telomere fusions in human b
Externí odkaz:
https://doaj.org/article/059ba90ad72f49779ec0d28617902a07
Autor:
Christopher Watson, Nazmul Huda, Melanie E. Alpuche, David Gilley, Jeremy B. Shapiro, Peter A. Crooks, Ronald H. Shapiro, Helen Chin-Sinex, Marc S. Mendonca, Imade E. Imasuen-Williams, William T. Turchan, Neil C. Estabrook, Gabriel Rangel
Publikováno v:
Free Radical Biology and Medicine. 112:318-326
Constitutive activation of the pro-survival transcription factor NF-κB has been associated with resistance to both chemotherapy and radiation therapy in many human cancers, including prostate cancer. Our lab and others have demonstrated that the nat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9ed7d208b5adfe4cb05ea3da0a9d20
https://doi.org/10.1016/j.freeradbiomed.2017.08.001
https://doi.org/10.1016/j.freeradbiomed.2017.08.001
Publikováno v:
Cells, Vol 8, Iss 5, p 414 (2019)
Cells
Volume 8
Issue 5
Cells
Volume 8
Issue 5
Telomere dysfunction has been strongly implicated in the initiation of genomic instability and is suspected to be an early event in the carcinogenesis of human solid tumors. Recent findings have established the presence of telomere fusions in human b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2fb96608f53c5ad8ecd99f07f241f2f
https://www.mdpi.com/2073-4409/8/5/414
https://www.mdpi.com/2073-4409/8/5/414
Autor:
Gil Atzmon, Rosalind Ramsey-Goldman, Barry J. McDonnell, Yun-Ling Zheng, David Gilley, Teresa E. Seeman, Maciej Tomaszewski, Massimo Mangino, Geja J. Hageman, Florian Kronenberg, Iiris Hovatta, Giuseppe Paolisso, Line Rode, Ellen W. Demerath, Jaakko Kaprio, Katarina Nordfjäll, Jonathan N. Hofmann, Peter Willeit, Rosana Maria dos Reis, Barbara Kollerits, Andrea Elena Iglesias Molli, Guo Cheng, Wei Zheng, Karen A. Mather, Daniel Eisenberg, Fadi J. Charchar, Sarah E. Harris, Bianca D’Antono, Jason Y.Y. Wong, Sofia Pavanello, Lisa A. Boardman, Guillaume Paré, Jacob B. H. Hjelmborg, Erik J. Giltay, Tim De Meyer, Evangelia Antoniou, Dmytro Krasnienkov, Maurice P. Zeegers, Marek Kasielski, Audrey E. Hendricks, Linda Broer, Lifang Hou, Andrew Steptoe, Andrew J. Pellatt, Jennifer A. Nettleton, Vanessa A. Diaz, Steven C. Hunt, Marij Gielen, Josine E. Verhoeven, Christian Gieger, Roxanne Schaakxs, Belinda L. Needham, Catherine Duggan, Timo E. Strandberg, Ute Mons, Klelia D. Salpea, Jeremy D. Kark, Raffaela Zannolli, Muthuswamy Balasubramanyam, Michael Chong, Richard P. Ebstein, Daniel Bunout, Amelia Marti, Kristina Sundquist, Lisa Mirabello, Hisham Nassar, David J. Kurz, Ramin Farzaneh-Far, Ilja Demuth, Pim van der Harst
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Christensen, K & TELOMAAS group 2018, ' Body mass index is negatively associated with telomere length : A collaborative cross-sectional meta-analysis of 87 observational studies ', American Journal of Clinical Nutrition, vol. 108, no. 3, pp. 453-475 . https://doi.org/10.1093/ajcn/nqy107
American Journal of Clinical Nutrition, 108(3), 453-475
Gielen, M, Hageman, G J, Antoniou, E E, Nordfjall, K, Mangino, M, Balasubramanyam, M, De Meyer, T, Hendricks, A E, Giltay, E J, Hunt, S C, Nettleton, J A, Salpea, K D, Diaz, V A, Farzaneh-far, R, Atzmon, G, Harris, S E, Hou, L, Gilley, D, Hovatta, I, Kark, J D, Nassar, H, Kurz, D J, Mather, K A, Willeit, P, Zheng, Y, Pavanello, S, Demerath, E W, Rode, L, Bunout, D, Steptoe, A, Boardman, L, Marti, A, Needham, B, Zheng, W, Ramsey-goldman, R, Pellatt, A J, Kaprio, J, Hofmann, J N, Gieger, C, Paolisso, G, Hjelmborg, J B H, Mirabello, L, Seeman, T, Wong, J, Van Der Harst, P, Broer, L, Kronenberg, F, Kollerits, B, Strandberg, T, Eisenberg, D T A, Duggan, C, Verhoeven, J E, Schaakxs, R, Zannolli, R, Dos Reis, R M R, Charchar, F J, Tomaszewski, M, Mons, U, Demuth, I, Molli, A E I, Cheng, G, Krasnienkov, D, D'antono, B, Kasielski, M, Mcdonnell, B J, Ebstein, R P, Sundquist, K, Pare, G, Chong, M & Zeegers, M P 2018, ' Body mass index is negatively associated with telomere length: a collaborative cross-sectional meta-analysis of 87 observational studies ', The American journal of clinical nutrition, vol. 108, no. 3, pp. 453-475 . https://doi.org/10.1093/ajcn/nqy107
TELOMAAS group 2018, ' Body mass index is negatively associated with telomere length: A collaborative cross-sectional meta-analysis of 87 observational studies ', American Journal of Clinical Nutrition, vol. 108, no. 3, pp. 453-475 . https://doi.org/10.1093/ajcn/nqy107
American Journal of Clinical Nutrition, 108(3), 453-475. Oxford University Press
American Journal of Clinical Nutrition
The American Journal of Clinical Nutrition
American Journal of Clinical Nutrition, 108(3), 453-475. American Society for Nutrition
Universidade de São Paulo (USP)
instacron:USP
Christensen, K & TELOMAAS group 2018, ' Body mass index is negatively associated with telomere length : A collaborative cross-sectional meta-analysis of 87 observational studies ', American Journal of Clinical Nutrition, vol. 108, no. 3, pp. 453-475 . https://doi.org/10.1093/ajcn/nqy107
American Journal of Clinical Nutrition, 108(3), 453-475
Gielen, M, Hageman, G J, Antoniou, E E, Nordfjall, K, Mangino, M, Balasubramanyam, M, De Meyer, T, Hendricks, A E, Giltay, E J, Hunt, S C, Nettleton, J A, Salpea, K D, Diaz, V A, Farzaneh-far, R, Atzmon, G, Harris, S E, Hou, L, Gilley, D, Hovatta, I, Kark, J D, Nassar, H, Kurz, D J, Mather, K A, Willeit, P, Zheng, Y, Pavanello, S, Demerath, E W, Rode, L, Bunout, D, Steptoe, A, Boardman, L, Marti, A, Needham, B, Zheng, W, Ramsey-goldman, R, Pellatt, A J, Kaprio, J, Hofmann, J N, Gieger, C, Paolisso, G, Hjelmborg, J B H, Mirabello, L, Seeman, T, Wong, J, Van Der Harst, P, Broer, L, Kronenberg, F, Kollerits, B, Strandberg, T, Eisenberg, D T A, Duggan, C, Verhoeven, J E, Schaakxs, R, Zannolli, R, Dos Reis, R M R, Charchar, F J, Tomaszewski, M, Mons, U, Demuth, I, Molli, A E I, Cheng, G, Krasnienkov, D, D'antono, B, Kasielski, M, Mcdonnell, B J, Ebstein, R P, Sundquist, K, Pare, G, Chong, M & Zeegers, M P 2018, ' Body mass index is negatively associated with telomere length: a collaborative cross-sectional meta-analysis of 87 observational studies ', The American journal of clinical nutrition, vol. 108, no. 3, pp. 453-475 . https://doi.org/10.1093/ajcn/nqy107
TELOMAAS group 2018, ' Body mass index is negatively associated with telomere length: A collaborative cross-sectional meta-analysis of 87 observational studies ', American Journal of Clinical Nutrition, vol. 108, no. 3, pp. 453-475 . https://doi.org/10.1093/ajcn/nqy107
American Journal of Clinical Nutrition, 108(3), 453-475. Oxford University Press
American Journal of Clinical Nutrition
The American Journal of Clinical Nutrition
American Journal of Clinical Nutrition, 108(3), 453-475. American Society for Nutrition
Background: Even before the onset of age-related diseases, obesity might be a contributing factor to the cumulative burden of oxidative stress and chronic inflammation throughout the life course. Obesity may therefore contribute to accelerated shorte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fdf732c38593d0bc118ec9a93d2b12d
https://hdl.handle.net/1887/96085
https://hdl.handle.net/1887/96085
Autor:
Brenda R. Grimes, Roger B. Slee, Nazmul Huda, David Gilley, LiRen Tu, Liang Cheng, Alison M. Bates
Publikováno v:
Molecular Carcinogenesis. 55:842-852
A critical function of the telomere is to disguise chromosome ends from cellular recognition as double strand breaks, thereby preventing aberrant chromosome fusion events. Such chromosome end-to-end fusions are known to initiate genomic instability v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e94e64e52bb2c00893e89a5f0f4cb51
https://doi.org/10.1002/mc.22326
https://doi.org/10.1002/mc.22326
Autor:
Dinesh Yernool, Samrat Roy Choudhury, Yi Cui, Chiao-Ling Lo, Anoop Narayanan, Feng C. Zhou, Nazmul Huda, Joseph Irudayaraj, David Gilley
Publikováno v:
Oncotarget
// Samrat Roy Choudhury 1 , Yi Cui 1 , Anoop Narayanan 2 , David P. Gilley 3 , Nazmul Huda 3 , Chiao-Ling Lo 4 , Feng C. Zhou 4, 5 , Dinesh Yernool 2 , Joseph Irudayaraj 1 1 Department of Agricultural & Biological Engineering, Bindley Bioscience Cent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5fd59df37041f809ca205546de478e
https://pubmed.ncbi.nlm.nih.gov/27391261
https://pubmed.ncbi.nlm.nih.gov/27391261
Autor:
Nazmul Huda, David Gilley, Hiromi Tanaka, Matthew J. Beam, Satoshi Abe, Li Ren Tu, Brenda R. Grimes
Publikováno v:
Proceedings of the National Academy of Sciences. 109:14098-14103
Several lines of evidence suggest that defects in telomere maintenance play a significant role in the initiation of genomic instability during carcinogenesis. Although the general concept of defective telomere maintenance initiating genomic instabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f534a721a67c297251e403cb4bf6a591
https://doi.org/10.1073/pnas.1120062109
https://doi.org/10.1073/pnas.1120062109
Autor:
Michelle Dean, Ruiqiong Ye, Jeffrey D. Hamill, Eiji Kubota, Huong Muzik, Chris T. Williamson, LiRen Tu, Susan P. Lees-Miller, Alexander C. Klimowicz, Bruce C. McKay, Anthony M. Magliocco, D. Gwyn Bebb, David Gilley
Publikováno v:
EMBO Molecular Medicine
Poly-ADP ribose polymerase (PARP) inhibitors have shown promise in the treatment of human malignancies characterized by deficiencies in the DNA damage repair proteins BRCA1 and BRCA2 and preclinical studies have demonstrated the potential effectivene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4833a0585674f853608ae366a6a1f5c
https://doi.org/10.1002/emmm.201200229
https://doi.org/10.1002/emmm.201200229
Publikováno v:
Journal of Pediatric Urology. 5:374-377
Introduction The lower moiety of duplex kidney can be associated with ureteropelvic junction obstruction (UPJO). Surgical correction can be challenging in cases of incomplete duplication where the junction of the lower and upper pole ureters is proxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e261200e5cddd65eb67765490a9f25
https://doi.org/10.1016/j.jpurol.2009.02.205
https://doi.org/10.1016/j.jpurol.2009.02.205
Publikováno v:
Mechanisms of Ageing and Development. 129:27-34
Loss of telomere length homeostasis has been linked to age-related disease especially cancer. In this review, we discuss two major causes of telomere dysfunction that potentially lead to tumorigenesis: replicative aging and environmental assaults. Ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9babac6e5527b3f879e776bd6e3e2011
https://doi.org/10.1016/j.mad.2007.10.010
https://doi.org/10.1016/j.mad.2007.10.010