Zobrazeno 1 - 10
of 40
pro vyhledávání: '"David, Fernández de Sevilla"'
Autor:
María Portela-Lomba, Diana Simón, Marta Callejo-Móstoles, Gemma de la Fuente, David Fernández de Sevilla, Vega García-Escudero, M. Teresa Moreno-Flores, Javier Sierra
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-11 (2024)
Abstract A recent approach to promote central nervous system (CNS) regeneration after injury or disease is direct conversion of somatic cells to neurons. This is achieved by transduction of viral vectors that express neurogenic transcription factors.
Externí odkaz:
https://doaj.org/article/d2f411dcb97f4a008abac9ee9aca31ce
Autor:
José Antonio Noriega-Prieto, Laura Eva Maglio, Paloma Perez-Domper, José Carlos Dávila, Antonia Gutiérrez, Ignacio Torres-Alemán, David Fernández de Sevilla
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Insulin-like growth factor-I (IGF-I) plays a key role in the modulation of synaptic plasticity and is an essential factor in learning and memory processes. However, during aging, IGF-I levels are decreased, and the effect of this decrease in the indu
Externí odkaz:
https://doaj.org/article/a49a8675cbde4d53851bc82568d2d635
Autor:
Irene B. Maroto, Carlos Costas-Insua, Coralie Berthoux, Estefanía Moreno, Andrea Ruiz-Calvo, Carlos Montero-Fernández, Andrea Macías-Camero, Ricardo Martín, Nuria García-Font, José Sánchez-Prieto, Giovanni Marsicano, Luigi Bellocchio, Enric I. Canela, Vicent Casadó, Ismael Galve-Roperh, Ángel Núñez, David Fernández de Sevilla, Ignacio Rodríguez-Crespo, Pablo E. Castillo, Manuel Guzmán
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The type-1 cannabinoid receptor (CB1R) is widely expressed in excitatory and inhibitory nerve terminals, and by suppressing neurotransmitter release, its activation modulates neural circuits and brain function. While the interaction of CB1R
Externí odkaz:
https://doaj.org/article/de2f897065d34da0933b217db4f53983
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S319- (2023)
Externí odkaz:
https://doaj.org/article/c88021e9c82b4a069bd811a6b4725e64
Autor:
María Portela-Lomba, Diana Simón, David Fernández de Sevilla, Mª Teresa Moreno-Flores, Javier Sierra
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
An approach to generate new neurons after central nervous system injury or disease is direct reprogramming of the individual's own somatic cells into differentiated neurons. This can be achieved either by transduction of viral vectors that express ne
Externí odkaz:
https://doaj.org/article/8add2b1e57b647c6b4dd150d5303f65a
Autor:
Laura E Maglio, José A Noriega-Prieto, Irene B Maroto, Jesús Martin-Cortecero, Antonio Muñoz-Callejas, Marta Callejo-Móstoles, David Fernández de Sevilla
Publikováno v:
eLife, Vol 10 (2021)
Insulin-like growth factor-1 (IGF-1) plays a key role in synaptic plasticity, spatial learning, and anxiety-like behavioral processes. While IGF-1 regulates neuronal firing and synaptic transmission in many areas of the central nervous system, its si
Externí odkaz:
https://doaj.org/article/4f62044224414736b4d2eefc48745254
Autor:
José Antonio Noriega-Prieto, Laura Eva Maglio, Sara Ibáñez-Santana, David Fernández de Sevilla
Publikováno v:
Cells, Vol 11, Iss 10, p 1641 (2022)
Insulin-like growth factor-I (IGF-I) signaling plays a key role in learning and memory. IGF-I increases the spiking and induces synaptic plasticity in the mice barrel cortex (Noriega-Prieto et al., 2021), favoring the induction of the long-term poten
Externí odkaz:
https://doaj.org/article/85362226f1834d2a970d4af97b2fc436
Autor:
Andrea Díez-García, Natali Barros-Zulaica, Ángel Núñez, Washington Buño, David Fernández de Sevilla
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Externí odkaz:
https://doaj.org/article/adda9e3e5a144bd8a0508fbe3c220c90
Autor:
Jansen Fernandes, Ignacio Torres-Aleman, Jonathan A. Zegarra-Valdivia, Angel Nuñez, Laura Martinez-Rachadell, Laura Eva Maglio, Ana M. Fernandez, Jaime Pignatelli, Alfonso Araque, José A Noriega-Prieto, David Fernández de Sevilla
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
J Neurosci
instname
J Neurosci
Insulin-like growth factor-I (IGF-I) signaling plays a key role in learning and memory processes. While the effects of IGF-I on neurons have been studied extensively, the involvement of astrocytes in IGF-I signaling and the consequences on synaptic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b02ca85f3be48f3ac87ba33f0fa4a6
https://doi.org/10.1523/jneurosci.0005-21.2021
https://doi.org/10.1523/jneurosci.0005-21.2021
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Neuroscience
instname
Neuroscience
descripción no proporcionada por scopus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74735823c46440a6c64fc823fd0155ae
https://doi.org/10.1016/j.neuroscience.2020.10.006
https://doi.org/10.1016/j.neuroscience.2020.10.006