Zobrazeno 1 - 10
of 170
pro vyhledávání: '"David, Dombrowicz"'
Autor:
Alexandre Gallerand, Bastien Dolfi, Marion I. Stunault, Zakariya Caillot, Alexia Castiglione, Axelle Strazzulla, Chuqiao Chen, Gyu Seong Heo, Hannah Luehmann, Flora Batoul, Nathalie Vaillant, Adélie Dumont, Thomas Pilot, Johanna Merlin, Fairouz N. Zair, Jerome Gilleron, Adeline Bertola, Peter Carmeliet, Jesse W. Williams, Rafael J. Arguello, David Masson, David Dombrowicz, Laurent Yvan-Charvet, Denis Doyen, Arvand Haschemi, Yongjian Liu, Rodolphe R. Guinamard, Stoyan Ivanov
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Monocytes directly contribute to atherosclerosis development by their recruitment to plaques in which they differentiate into macrophages. In the present study, we ask how modulating monocyte glucose metabolism could affect their homeostasis
Externí odkaz:
https://doaj.org/article/75ff188150004c8a83111624efceb8a1
Autor:
Laurent L’homme, Benan Pelin Sermikli, Joel T. Haas, Sébastien Fleury, Sandrine Quemener, Valentine Guinot, Emelie Barreby, Nathalie Esser, Robert Caiazzo, Hélène Verkindt, Benjamin Legendre, Violeta Raverdy, Lydie Cheval, Nicolas Paquot, Jacques Piette, Sylvie Legrand-Poels, Myriam Aouadi, François Pattou, Bart Staels, David Dombrowicz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Plasma growth differentiation factor-15 (GDF-15) levels increase with obesity and metabolic dysfunction-associated steatotic liver disease (MASLD) but the underlying mechanism remains poorly defined. Using male mouse models of obesity and MA
Externí odkaz:
https://doaj.org/article/0165911603514238b8604a2d501f0ef0
Autor:
Sandro Ninni, Rocio Vicario, Augustin Coisne, Eloise Woitrain, Amine Tazibet, Caitlin M. Stewart, Luis A. Diaz, James Robert White, Mohammed Koussa, Henri Dubrulle, Francis Juthier, Marie Jungling, André Vincentelli, Jean‐Louis Edme, Stanley Nattel, Menno de Winther, Frederic Geissmann, David Dombrowicz, Bart Staels, David Montaigne
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 17 (2024)
Background Cardiac surgery triggers sterile innate immune responses leading to postoperative complications. Clonal hematopoiesis (CH) is associated with short‐term inflammation‐mediated outcomes after cardiac surgery. The impact of CH on long‐t
Externí odkaz:
https://doaj.org/article/a1418df6d5004fd7b9ce2c224f10bced
Autor:
Hélène Dehondt, Arianna Marino, Laura Butruille, Denis A. Mogilenko, Arielle C. Nzoussi Loubota, Oscar Chávez-Talavera, Emilie Dorchies, Emmanuelle Vallez, Joel Haas, Bruno Derudas, Antonino Bongiovanni, Meryem Tardivel, Folkert Kuipers, Philippe Lefebvre, Sophie Lestavel, Anne Tailleux, David Dombrowicz, Sandrine Caron, Bart Staels
Publikováno v:
Molecular Metabolism, Vol 85, Iss , Pp 101961- (2024)
Externí odkaz:
https://doaj.org/article/fcbc82ce3f4948188786f7d4352a0ee8
Autor:
Dan Van Bui, Linh Manh Nguyen, Akira Kanda, Hanh Hong Chu, Nhi Kieu Thi Le, Yasutaka Yun, Yoshiki Kobayashi, Kensuke Suzuki, Akitoshi Mitani, Akihiro Shimamura, Kenta Fukui, Shunsuke Sawada, David Dombrowicz, Hiroshi Iwai
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 360 (2024)
Introduction: Eosinophils contribute to the pathogenesis of allergic diseases, including asthma, allergic rhinitis, and atopic dermatitis. We previously reported that human tissue eosinophils have high CD69 expression compared to blood eosinophils, a
Externí odkaz:
https://doaj.org/article/26164cae65be4b28a44ce8ee6b064145
Autor:
Frédérik Oger, Maeva Moreno, Mehdi Derhourhi, Bryan Thiroux, Lionel Berberian, Cyril Bourouh, Emmanuelle Durand, Souhila Amanzougarene, Alaa Badreddine, Etienne Blanc, Olivier Molendi-Coste, Laurent Pineau, Gianni Pasquetti, Laure Rolland, Charlène Carney, Florine Bornaque, Emilie Courty, Céline Gheeraert, Jérôme Eeckhoute, David Dombrowicz, Julie Kerr-Conte, François Pattou, Bart Staels, Philippe Froguel, Amélie Bonnefond, Jean-Sébastien Annicotte
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107231- (2023)
Summary: Histone deacetylases enzymes (HDACs) are chromatin modifiers that regulate gene expression through deacetylation of lysine residues within specific histone and non-histone proteins. A cell-specific gene expression pattern defines the identit
Externí odkaz:
https://doaj.org/article/75620a5d73cf44908a7169d2d5030f87
Autor:
Erwan Goy, Nathalie Martin, Claire Drullion, Laure Saas, Olivier Molendi-Coste, Laurent Pineau, David Dombrowicz, Emeric Deruy, Hélène Bauderlique-Leroy, Olivier Samyn, Joe Nassour, Yvan de Launoit, Corinne Abbadie
Publikováno v:
Bio-Protocol, Vol 13, Iss 7 (2023)
Cellular senescence is a reprogrammed cell state triggered as an adaptative response to a variety of stresses, most often those affecting the genome integrity. Senescent cells accumulate in most tissues with age and contribute to the development of s
Externí odkaz:
https://doaj.org/article/aa8efd80d23e45ca81a79e774582716a
Autor:
Hélène Dehondt, Arianna Marino, Laura Butruille, Denis A. Mogilenko, Arielle C. Nzoussi Loubota, Oscar Chávez-Talavera, Emilie Dorchies, Emmanuelle Vallez, Joel Haas, Bruno Derudas, Antonino Bongiovanni, Meryem Tardivel, Folkert Kuipers, Philippe Lefebvre, Sophie Lestavel, Anne Tailleux, David Dombrowicz, Sandrine Caron, Bart Staels
Publikováno v:
Molecular Metabolism, Vol 69, Iss , Pp 101686- (2023)
Objective: Obesity is associated with metabolic dysfunction of white adipose tissue (WAT). Activated adipocytes secrete pro-inflammatory cytokines resulting in the recruitment of pro-inflammatory macrophages, which contribute to WAT insulin resistanc
Externí odkaz:
https://doaj.org/article/ade14d0595004d0f98f05cbe5f0a6024
Publikováno v:
Haematologica, Vol 108, Iss 7 (2023)
Externí odkaz:
https://doaj.org/article/567a4ec785b442fb91492e23899117ff
Autor:
Alexandre Gallerand, Marion I. Stunault, Johanna Merlin, Hannah P. Luehmann, Deborah H. Sultan, Maria M. Firulyova, Virginie Magnone, Narges Khedher, Antoine Jalil, Bastien Dolfi, Alexia Castiglione, Adelie Dumont, Marion Ayrault, Nathalie Vaillant, Jérôme Gilleron, Pascal Barbry, David Dombrowicz, Matthias Mack, David Masson, Thomas Bertero, Burkhard Becher, Jesse W. Williams, Konstantin Zaitsev, Yongjian Liu, Rodolphe R. Guinamard, Laurent Yvan-Charvet, Stoyan Ivanov
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Adipose tissue is composed of a number of adipocytes and a number of other cells including immune cells. Here the authors use single-cell sequencing of murine brown adipose tissue immune cells and describe multiple macrophage and monocyte subsets and
Externí odkaz:
https://doaj.org/article/e27f3045057046fd93f4d2ad42eab91a