Zobrazeno 1 - 10
of 93
pro vyhledávání: '"David, DeShazer"'
Autor:
Christopher K. Cote, Kevin D. Mlynek, Christopher P. Klimko, Sergei S. Biryukov, Sherry Mou, Melissa Hunter, Nathaniel O. Rill, Jennifer L. Dankmeyer, Jeremey A. Miller, Yuli Talyansky, Michael L. Davies, J. Matthew Meinig, Stephanie A. Halasohoris, Anette M. Gray, Jade L. Spencer, Ashley L. Babyak, M. Kelly Hourihan, Bobby J. Curry, Ronald G. Toothman, Sara I. Ruiz, Xiankun Zeng, Keersten M. Ricks, Tamara L. Clements, Christina E. Douglas, Suma Ravulapalli, Christopher P. Stefan, Charles J. Shoemaker, Mindy G. Elrod, Jay E. Gee, Zachary P. Weiner, Ju Qiu, Joel A. Bozue, Nancy A. Twenhafel, David DeShazer
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 10, Pp 2056-2069 (2024)
In the United States in 2021, an outbreak of 4 cases of Burkholderia pseudomallei, the etiologic agent of melioidosis and a Tier One Select Agent (potential for deliberate misuse and subsequent harm), resulted in 2 deaths. The causative strain, B. ps
Externí odkaz:
https://doaj.org/article/8ea8582aa67e4680aa3494f13afc1315
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Melioidosis is caused by Burkholderia pseudomallei, an opportunistic Gram-negative pathogen that inhabits soil and water in tropical and subtropical regions. B. pseudomallei infections often occur following contact with contaminated water or soil or
Externí odkaz:
https://doaj.org/article/e5c5f89aa99c49e08634b66c074c0083
Autor:
Christopher P. Klimko, Jennifer L. Shoe, Nathaniel O. Rill, Melissa Hunter, Jennifer L. Dankmeyer, Yuli Talyansky, Lindsey K. Schmidt, Caitlyn E. Orne, David P. Fetterer, Sergei S. Biryukov, Mary N. Burtnick, Paul J. Brett, David DeShazer, Christopher K. Cote
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Burkholderia pseudomallei, the gram-negative bacterium that causes melioidosis, is notoriously difficult to treat with antibiotics. A significant effort has focused on identifying protective vaccine strategies to prevent melioidosis. However, when us
Externí odkaz:
https://doaj.org/article/e2bc4f0c829d4ebdb60a3308f946b386
Autor:
Sergei S. Biryukov, Christopher K. Cote, Christopher P. Klimko, Jennifer L. Dankmeyer, Nathaniel O. Rill, Jennifer L. Shoe, Melissa Hunter, Zain Shamsuddin, Ivan Velez, Zander M. Hedrick, Raysa Rosario-Acevedo, Yuli Talyansky, Lindsey K. Schmidt, Caitlyn E. Orne, David P. Fetterer, Mary N. Burtnick, Paul J. Brett, Susan L. Welkos, David DeShazer
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Burkholderia pseudomallei and the closely related species, Burkholderia mallei, produce similar multifaceted diseases which range from rapidly fatal to protracted and chronic, and are a major cause of mortality in endemic regions. Besides causing nat
Externí odkaz:
https://doaj.org/article/ca916529189043a0a6727d77d964e0ef
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 1041-1058 (2020)
Burkholderia pseudomallei: is the etiological agent of the disease melioidosis and is a Tier 1 select agent. It survives and replicates inside phagocytic cells by escaping from the endocytic vacuole, replicating in the cytosol, spreading to other cel
Externí odkaz:
https://doaj.org/article/845a4c2cc6864435801d22a1da290842
Autor:
Kei Amemiya, Jennifer L. Dankmeyer, Robert C. Bernhards, David P. Fetterer, David M. Waag, Patricia L. Worsham, David DeShazer
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Successful bacterial pathogens have evolved to avoid activating an innate immune system in the host that responds to the pathogen through distinct Toll-like receptors (TLRs). The general class of biochemical components that activate TLRs has been stu
Externí odkaz:
https://doaj.org/article/7b8d0c605ec6434596bda02c04bdec75
Autor:
Sherry Mou, Conor C. Jenkins, Udoka Okaro, Elizabeth S. Dhummakupt, Phillip M. Mach, David DeShazer
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 1 (2021)
ABSTRACT Burkholderia pseudomallei is an opportunistic pathogen that is responsible for the disease melioidosis in humans and animals. The microbe is a tier 1 select agent because it is highly infectious by the aerosol route, it is inherently resista
Externí odkaz:
https://doaj.org/article/6e371b2f607a46cbb6896f3cd52d1541
Autor:
Christopher P. Klimko, Susan L. Welkos, Jennifer L. Shoe, Sherry Mou, Melissa Hunter, Nathaniel O. Rill, David DeShazer, Christopher K. Cote
Publikováno v:
Antibiotics, Vol 11, Iss 12, p 1685 (2022)
The microbial pathogens Burkholderia pseudomallei and Bacillus anthracis are unrelated bacteria, yet both are the etiologic agents of naturally occurring diseases in animals and humans and are classified as Tier 1 potential biothreat agents. B. pseud
Externí odkaz:
https://doaj.org/article/341d11acd1a44851974c843fa02b62b7
TheBurkholderia pseudomalleicomplex (Bpc) includesB. pseudomallei, B. malleiandB. thailandensis. These species share conserved virulence determinants that facilitate survival in mammalian cells and can spread from cell to cell by a unique mechanism i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c283d6d9445d79b7badff370c505acc
https://doi.org/10.1101/2023.02.09.527577
https://doi.org/10.1101/2023.02.09.527577
Autor:
Jennifer Chua, Ethan Nguyenkhoa, Sherry Mou, Steven A. Tobery, Arthur M. Friedlander, David DeShazer
Publikováno v:
Infect Immun
Burkholderia pseudomallei, the causative agent of melioidosis, is classified by the CDC as a tier 1 select agent, and work involving it must be performed in a biosafety level 3 (BSL-3) laboratory. Three BSL-2 surrogate strains derived from B. pseudom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c75fc89299683a6e45804f7ad2a6bd9
https://doi.org/10.1128/iai.00159-22
https://doi.org/10.1128/iai.00159-22