Zobrazeno 1 - 10
of 352
pro vyhledávání: '"David, Díez"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 1880-1893 (2024)
The concept of bioisostere replacement is of paramount importance in medicinal chemistry, as it can be employed as a rational to expand bioactive chemical space to tackle lead optimization issues like lack of potency, efficacy, and selectivity or pha
Externí odkaz:
https://doaj.org/article/dcf21fb89c64495497cc814b170f7757
Autor:
David Díez
Publikováno v:
Revista Interamericana de Bibliotecología, Vol 47, Iss 1, Pp 1-16 (2023)
Los mecanismos alternativos para la resolución de conflictos, como la conciliación, son más eficientes y efectivos cuando las partes cuentan con altos niveles de inteligencia emocional. A su vez, la práctica de mindfulness contribuye al desarroll
Externí odkaz:
https://doaj.org/article/85067846fe5e4a25b05084fded011f7b
Autor:
David, Díez
Publikováno v:
David, Díez Cómo aplicar la tecnología del mindfulness en la preconciliación aportes de publicaciones internacionales. Revista Interamericana de Bibliotecología, 2023, vol. 47, n. 1, pp. 1-16. [Journal article (Paginated)]
Alternative dispute resolution, such as conciliation, are more efficient and effective when the parties have high levels of emotional intelligence. Likewise, the practice of mindfulness contributes to the development of that intelligence. Hence, the
Externí odkaz:
http://eprints.rclis.org/45533/
Publikováno v:
Revista de Ciencias Sociales, Vol 29, Iss 2, Pp 277-296 (2023)
La innovación social genera nuevas soluciones para el logro de Objetivos de Desarrollo Sostenible. Empero, poco se conocen los aportes del emprendimiento a la innovación social en contextos de postconflicto como el colombiano. Así, el objetivo del
Externí odkaz:
https://doaj.org/article/a7eccedba64242ab85844ee129267c26
Autor:
David Díez Gómez
Publikováno v:
Géneroos, Vol 15, Iss 4 (2023)
A partir de algunas entrevistas a jóvenes ne gras vinculadas al trabajo doméstico en casas de terceros, tomadas de estudios realizados en Colombia y en otros países del continente americano, en este ensayo se argumenta que el trabajo doméstico
Externí odkaz:
https://doaj.org/article/7feccd75d74a4906bc9cb2a19adfe24d
Autor:
Carolina Miranda-Vera, Ángela Patricia Hernández, Pilar García-García, David Díez, Pablo Anselmo García, María Ángeles Castro
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2728 (2023)
Podophyllotoxin is a naturally occurring cyclolignan isolated from rhizomes of Podophyllum sp. In the clinic, it is used mainly as an antiviral; however, its antitumor activity is even more interesting. While podophyllotoxin possesses severe side eff
Externí odkaz:
https://doaj.org/article/5b887b0a597242938e30e17a61fcc919
Autor:
Verena E. Kutschera, Marcin Kierczak, Tom van der Valk, Johanna von Seth, Nicolas Dussex, Edana Lord, Marianne Dehasque, David W. G. Stanton, Payam Emami Khoonsari, Björn Nystedt, Love Dalén, David Díez-del-Molino
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Background Many wild species have suffered drastic population size declines over the past centuries, which have led to ‘genomic erosion’ processes characterized by reduced genetic diversity, increased inbreeding, and accumulation of harm
Externí odkaz:
https://doaj.org/article/cd40e0643311421e8edf12c3f8400a40
Autor:
Tom van der Valk, Marianne Dehasque, J. Camilo Chacón-Duque, Nikolay Oskolkov, Sergey Vartanyan, Peter D. Heintzman, Patrícia Pečnerová, David Díez-del-Molino, Love Dalén
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104826- (2022)
Summary: Woolly mammoths had a set of adaptations that enabled them to thrive in the Arctic environment. Many mammoth-specific single nucleotide polymorphisms (SNPs) responsible for unique mammoth traits have been previously identified from ancient g
Externí odkaz:
https://doaj.org/article/d85bad0d77354ef2a4be1790a224d17d
Autor:
Johanna von Seth, Nicolas Dussex, David Díez-del-Molino, Tom van der Valk, Verena E. Kutschera, Marcin Kierczak, Cynthia C. Steiner, Shanlin Liu, M. Thomas P. Gilbert, Mikkel-Holger S. Sinding, Stefan Prost, Katerina Guschanski, Senthilvel K. S. S. Nathan, Selina Brace, Yvonne L. Chan, Christopher W. Wheat, Pontus Skoglund, Oliver A. Ryder, Benoit Goossens, Anders Götherström, Love Dalén
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Highly endangered species like the Sumatran rhinoceros are at risk from inbreeding. Five historical and 16 modern genomes from across the species range show mutational load, but little evidence for local adaptation, suggesting that future inbreeding
Externí odkaz:
https://doaj.org/article/2ca4ea65799945a881d363596de220e7
Autor:
Ángela-Patricia Hernández, Paula Díez, Pablo A. García, Martín Pérez-Andrés, Anzhela Veselinova, Pablo G. Jambrina, Arturo San Feliciano, David Díez, Manuel Fuentes, Mᵃ Ángeles Castro
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 886 (2023)
New lignohydroquinone conjugates (L-HQs) were designed and synthesized using the hybridization strategy, and evaluated as cytotoxics against several cancer cell lines. The L-HQs were obtained from the natural product podophyllotoxin and some semisynt
Externí odkaz:
https://doaj.org/article/c9850c81e4d943de8dcea844f62c72a5