Zobrazeno 1 - 10
of 172
pro vyhledávání: '"David, Creytens"'
Autor:
Bliede Van den Broeck, Jens M. Debacker, Wouter Bauters, David Creytens, Liesbeth Ferdinande, Wouter Huvenne, Bruno Lapauw, Vanessa Schelfhout, Nick Van Laeken, Charlotte Verroken
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Background Patients diagnosed with radioiodine refractory (RAI-R) thyroid carcinoma (TC) have a significantly worse prognosis than patients with radiosensitive TC. These refractory malignancies are often dedifferentiated, hindering the effec
Externí odkaz:
https://doaj.org/article/6a52e39f81a64f3dbea5cfeedb8d2304
Autor:
Suzanne Fischer, David Creytens, Stefanie Gijsels, Benedicte Descamps, Lore Lapeire, An Hendrix, Gwen Sys, Olivier De Wever
Publikováno v:
STAR Protocols, Vol 5, Iss 1, Pp 102863- (2024)
Summary: Despite optimal multimodal treatment including surgical resection, 50%–80% of high-grade soft tissue sarcoma (STS) patients metastasize. Here, we present a protocol for the generation and use of post-surgical minimal residual disease model
Externí odkaz:
https://doaj.org/article/ffa25ef0daa54c2c8768649e70a9df62
Autor:
Jeroen Vierstraete, Charlotte Fieuws, David Creytens, Jo Van Dorpe, Andy Willaert, Anne Vral, Kathleen BM Claes
Publikováno v:
Genes and Diseases, Vol 10, Iss 2, Pp 381-384 (2023)
Externí odkaz:
https://doaj.org/article/6d4bde0fbcda483dac1a3d72acbdaf6b
Autor:
Bieke Decaesteker, Amber Louwagie, Siebe Loontiens, Fanny De Vloed, Sarah-Lee Bekaert, Juliette Roels, Suzanne Vanhauwaert, Sara De Brouwer, Ellen Sanders, Alla Berezovskaya, Geertrui Denecker, Eva D’haene, Stéphane Van Haver, Wouter Van Loocke, Jo Van Dorpe, David Creytens, Nadine Van Roy, Tim Pieters, Christophe Van Neste, Matthias Fischer, Pieter Van Vlierberghe, Stephen S. Roberts, Johannes Schulte, Sara Ek, Rogier Versteeg, Jan Koster, Johan van Nes, Mark Zimmerman, Katleen De Preter, Frank Speleman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
The development of neuroblastoma (NB) is regulated by multiple core transcription factors. Here, SOX11 is identified as a potential epigenetic master regulator upstream of the core regulatory circuitry in adrenergic high-risk neuroblastoma.
Externí odkaz:
https://doaj.org/article/c5e038d1e2b747e4b27f9e8e90add70c
Autor:
Sofia Maria Lider Burciulescu, Caren Randon, Frederic Duprez, Wouter Huvenne, David Creytens, Kathleen B M Claes, Robin de Putter, Guy T’Sjoen, Corin Badiu, Bruno Lapauw
Publikováno v:
Endocrine Oncology, Vol 3, Iss 1, Pp 1-9 (2023)
Pheochromocytomas (PHEO) and paragangliomas (PGL) can occur sporadic or within genetic predisposition syndromes. Despite shared embryology, there are important differences between PHEO and PGL. The aim of this study was to describe the clinical prese
Externí odkaz:
https://doaj.org/article/e1713b97eb664231a2605edc598efa94
Autor:
Suzanne Fischer, David Creytens, Sofie De Geyter, Elly De Vlieghere, Piet Pattyn, Sarah‐Lee Bekaert, Kaat Durinck, Nadine Van Roy, An Hendrix, Lore Lapeire, Gwen Sys, Olivier De Wever
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 6, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/9bdda4c51f824d7caade00dc99552043
Autor:
Astrid De Meulenaere, Tijl Vermassen, David Creytens, Stijn De Keukeleire, Tim Delahaye, Philippe Deron, Fréderic Duprez, Samson Fung, Patrick Pauwels, Liesbeth Ferdinande, Sylvie Rottey
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 6, Pp 2300-2313 (2021)
Abstract CD70 is expressed in up to 80% of nasopharyngeal carcinoma (NPC) cases. Cusatuzumab is a humanized anti‐CD70 monoclonal antibody, with dual action mechanisms: induction of cytotoxicity against CD70+ tumor cells and reduction in CD70‐CD27
Externí odkaz:
https://doaj.org/article/d937f00205db456b849d7045bb391b76
Autor:
Anneleen Decock, David Creytens, Steve Lefever, Joni Van der Meulen, Jasper Anckaert, Ariane De Ganck, Jill Deleu, Bram De Wilde, Carolina Fierro, Scott Kuersten, Manuel Luypaert, Isabelle Rottiers, Gary P. Schroth, Sandra Steyaert, Katrien Vanderheyden, Eveline Vanden Eynde, Kimberly Verniers, Joke Verreth, Jo Van Dorpe, Jo Vandesompele
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11007 (2022)
We assess the performance of mRNA capture sequencing to identify fusion transcripts in FFPE tissue of different sarcoma types, followed by RT-qPCR confirmation. To validate our workflow, six positive control tumors with a specific chromosomal rearran
Externí odkaz:
https://doaj.org/article/b547c75db1ae4b15b77ed6e971f9d012
Autor:
Giulia Ascari, Nanna D. Rendtorff, Marieke De Bruyne, Julie De Zaeytijd, Michel Van Lint, Miriam Bauwens, Mattias Van Heetvelde, Gavin Arno, Julie Jacob, David Creytens, Jo Van Dorpe, Thalia Van Laethem, Toon Rosseel, Tim De Pooter, Peter De Rijk, Wouter De Coster, Björn Menten, Alfredo Dueñas Rey, Mojca Strazisar, Mette Bertelsen, Lisbeth Tranebjaerg, Elfride De Baere
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Inactivating variants as well as a missense variant in the centrosomal CEP78 gene have been identified in autosomal recessive cone-rod dystrophy with hearing loss (CRDHL), a rare syndromic inherited retinal disease distinct from Usher syndrome. Apart
Externí odkaz:
https://doaj.org/article/483ae383a34a48e1a6bbe9032362f8b3
Publikováno v:
Case Reports in Oncological Medicine, Vol 2021 (2021)
Background. Clear cell chondrosarcoma (CCCS) is a rare subtype of chondrosarcoma and comprises between 1.6% and 2.5% of all chondrosarcoma. They are known to be chemo- and radiotherapy resistant; surgical resection is therefore the therapy of choice.
Externí odkaz:
https://doaj.org/article/60f13007e1154d5ab670d03adb7bfdda